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2AZE
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BU of 2aze by Molmil
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Descriptor: Retinoblastoma-associated protein, Transcription factor Dp-1, Transcription factor E2F1
Authors:Rubin, S.M, Gall, A.L, Zheng, N, Pavletich, N.P.
Deposit date:2005-09-10
Release date:2006-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Cell(Cambridge,Mass.), 123, 2005
6G0P
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BU of 6g0p by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated E2F1 peptide (K117ac/K120ac)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Transcription factor E2F1
Authors:Filippakopoulos, P, Picaud, S, Krojer, T, Sorrell, F, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
Deposit date:2018-03-19
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
6ULS
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BU of 6uls by Molmil
BRD4-BD1 in complex with the a diacetylated-E2F1 peptide
Descriptor: Bromodomain-containing protein 4, Diacetylated E2F1 Peptide (K117ac and K120ac)
Authors:Patel, K, Low, J.K.K, Mackay, J.P.
Deposit date:2019-10-08
Release date:2020-08-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.
Biochemistry, 60, 2021
1H24
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BU of 1h24 by Molmil
CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, TRANSCRIPTION FACTOR E2F1
Authors:Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
Deposit date:2002-07-31
Release date:2003-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1O9K
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BU of 1o9k by Molmil
Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
Descriptor: RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
Authors:Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
Deposit date:2002-12-16
Release date:2003-03-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
5GOW
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BU of 5gow by Molmil
Solution structure of the complex between DP1 acidic region and TFIIH p62 PH domain
Descriptor: DP1, General transcription factor IIH subunit 1
Authors:Okuda, M, Nishimura, Y.
Deposit date:2016-07-29
Release date:2016-12-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH
J. Mol. Biol., 428, 2016
4V8P
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BU of 4v8p by Molmil
T.thermophila 60S ribosomal subunit in complex with initiation factor 6.
Descriptor: 26S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N.
Deposit date:2011-09-14
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6.
Science, 334, 2011
1H27
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BU of 1h27 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p27
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, CYCLIN-DEPENDENT KINASE INHIBITOR 1B
Authors:Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
Deposit date:2002-07-31
Release date:2003-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H25
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BU of 1h25 by Molmil
CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN
Authors:Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
Deposit date:2002-07-31
Release date:2003-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H28
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BU of 1h28 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p107
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-LIKE PROTEIN 1
Authors:Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
Deposit date:2002-07-31
Release date:2003-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H26
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BU of 1h26 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p53
Descriptor: CELL DIVISION PROTEIN KINASE 2, CELLULAR TUMOR ANTIGEN P53, CYCLIN A2
Authors:Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
Deposit date:2002-07-31
Release date:2003-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
3JVE
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BU of 3jve by Molmil
Crystal Structure of the Sixth BRCT Domain of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
5UFL
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BU of 5ufl by Molmil
Crystal structure of a CIP2A core domain
Descriptor: Protein CIP2A, ZINC ION
Authors:Wang, Z, Wang, J, Rao, Z, Xu, W.
Deposit date:2017-01-04
Release date:2017-02-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.
EMBO Rep., 18, 2017
7TOA
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BU of 7toa by Molmil
BRD3-BD1 in complex with RaPID linear peptide 3xAcK.1 (triAcK.1)
Descriptor: 3xAcK.1 (triAcK.1), Bromodomain-containing protein 3, GLYCEROL
Authors:Patel, K, Low, J.K.K, Mackay, J.P.
Deposit date:2022-01-23
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome.
J.Biol.Chem., 299, 2023

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PDB entries from 2024-05-15

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