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5VJX
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Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor
分子名称: CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H.
登録日2017-04-20
公開日2017-12-06
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
5VJI
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BU of 5vji by Molmil
Crystal structure of the CLOCK Transcription Domain Exon19 in Complex with a Repressor
分子名称: CLOCK-interacting pacemaker, Circadian locomoter output cycles protein kaput
著者Hou, Z, Su, L, Pei, J, Grishin, N.V, Zhang, H.
登録日2017-04-19
公開日2017-06-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor.
Structure, 25, 2017
4F3L
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BU of 4f3l by Molmil
Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex
分子名称: BMAL1b, Circadian locomoter output cycles protein kaput
著者Huang, N, Chelliah, Y, Shan, Y, Taylor, C, Yoo, S, Partch, C, Green, C.B, Zhang, H, Takahashi, J.
登録日2012-05-09
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.268 Å)
主引用文献Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
6QPJ
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BU of 6qpj by Molmil
Human CLOCK PAS-A domain
分子名称: Circadian locomoter output cycles protein kaput
著者Kwon, H, Freeman, S.L, Moody, P.C.E, Raven, E.L, Basran, J.
登録日2019-02-14
公開日2019-09-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Heme binding to human CLOCK affects interactions with the E-box.
Proc.Natl.Acad.Sci.USA, 116, 2019
4H10
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BU of 4h10 by Molmil
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA
分子名称: Aryl hydrocarbon receptor nuclear translocator-like protein 1, Circadian locomoter output cycles protein kaput, E-box DNA antisense strand, ...
著者Wang, Z, Su, X.-D.
登録日2012-09-10
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
Cell Res., 23, 2013
2GBL
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BU of 2gbl by Molmil
Crystal Structure of Full Length Circadian Clock Protein KaiC with Phosphorylation Sites
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION
著者Pattanayek, R, Williams, D.R, Pattanayek, S, Xu, Y, Mori, T, Johnson, C.H, Stewart, P.L, Egli, M.
登録日2006-03-10
公開日2007-01-23
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods.
Embo J., 25, 2006
4DUG
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BU of 4dug by Molmil
Crystal Structure of Circadian Clock Protein KaiC E318A Mutant
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION, ...
著者Egli, M, Mori, T, Pattanayek, R, Xu, Y, Qin, X, Johnson, C.H.
登録日2012-02-21
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.292 Å)
主引用文献Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism.
Biochemistry, 51, 2012
4G86
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BU of 4g86 by Molmil
Crystal structure of the redox-active cofactor DBMIB bound to the full length circadian clock protein KaiA from Synechococcus elongatus
分子名称: 2,5-DIBROMO-3-ISOPROPYL-6-METHYLBENZO-1,4-QUINONE, Circadian clock protein kaiA, GLYCEROL, ...
著者Pattanayek, R, Egli, M.
登録日2012-07-21
公開日2012-10-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.387 Å)
主引用文献Crystal Structure of the Redox-Active Cofactor Dibromothymoquinone Bound to Circadian Clock Protein KaiA and Structural Basis for Dibromothymoquinone's Ability to Prevent Stimulation of KaiC Phosphorylation by KaiA.
Biochemistry, 51, 2012
2QKE
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BU of 2qke by Molmil
Wild Type Crystal Structure of Full Length Circadian Clock Protein KaiB from Thermosynechococcus elongatus BP-1
分子名称: Circadian clock protein kaiB
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2007-07-10
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural model of the circadian clock KaiB-KaiC complex and mechanism for modulation of KaiC phosphorylation.
Embo J., 27, 2008
3JZM
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BU of 3jzm by Molmil
Crystal structure of the phosphorylation-site mutant T432A of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-23
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0F
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Crystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-24
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K09
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Crystal structure of the phosphorylation-site mutant S431D of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-24
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0C
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BU of 3k0c by Molmil
Crystal structure of the phosphorylation-site double mutant S431A/T432E of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-24
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0A
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BU of 3k0a by Molmil
Crystal structure of the phosphorylation-site mutant S431A of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-24
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
3K0E
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BU of 3k0e by Molmil
Crystal structure of the phosphorylation-site mutant T426N of the KaiC circadian clock protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M, Pattanayek, S.
登録日2009-09-24
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase.
Plos One, 4, 2009
7DYJ
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BU of 7dyj by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Furuike, Y, Akiyama, S.
登録日2021-01-22
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DYI
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BU of 7dyi by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Furuike, Y, Akiyama, S.
登録日2021-01-21
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DYK
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BU of 7dyk by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Furuike, Y, Akiyama, S.
登録日2021-01-22
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DXQ
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BU of 7dxq by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Furuike, Y, Akiyama, S.
登録日2021-01-20
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7DY2
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BU of 7dy2 by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ...
著者Furuike, Y, Akiyama, S.
登録日2021-01-20
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7V3X
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BU of 7v3x by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ...
著者Furuike, Y, Akiyama, S.
登録日2021-08-11
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Elucidation of master allostery essential for circadian clock oscillation in cyanobacteria.
Sci Adv, 8, 2022
7WDC
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BU of 7wdc by Molmil
Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Furuike, Y, Akiyama, S.
登録日2021-12-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system.
Biochem.J., 479, 2022
5C5E
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BU of 5c5e by Molmil
Structure of KaiA dimer in complex with C-terminal KaiC peptide at 2.8 A resolution
分子名称: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(sulfanylcarbonyl)amino]benzoic acid, Circadian clock protein KaiA, KaiC C-terminal peptide
著者Pattanayek, R, Egli, M.
登録日2015-06-19
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 angstrom Resolution.
Biochemistry, 54, 2015
8FWJ
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BU of 8fwj by Molmil
Structure of dodecameric KaiC-RS-S413E/S414E complexed with KaiB-RS solved by cryo-EM
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiB, ...
著者Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
登録日2023-01-22
公開日2023-03-22
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献From primordial clocks to circadian oscillators.
Nature, 616, 2023
4O0M
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BU of 4o0m by Molmil
Crystal structure of T. Elongatus BP-1 Clock Protein KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Pattanayek, R, Egli, M.
登録日2013-12-13
公開日2014-05-14
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC
Acta Crystallogr.,Sect.D, D70, 2014

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