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5VRP
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BU of 5vrp by Molmil
Crystal Structure of Human Renin in Complex with a biphenylpipderidinylcarbinol
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, SULFATE ION, ...
Authors:Concha, N, Zhao, B.
Deposit date:2017-05-11
Release date:2017-10-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition.
Bioorg. Med. Chem. Lett., 27, 2017
5VSK
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BU of 5vsk by Molmil
Structure of DUB complex
Descriptor: 7-chloro-3-({4-hydroxy-1-[(3S)-3-phenylbutanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION
Authors:Seo, H.-Y, Dhe-Paganon, S.
Deposit date:2017-05-11
Release date:2017-12-20
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
5VSX
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BU of 5vsx by Molmil
Structure of the Ubl domain of Sacsin
Descriptor: Sacsin
Authors:Trempe, J.-F, Pande, H, Shenker, S, Gehring, K.
Deposit date:2017-05-13
Release date:2017-05-31
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
5W2F
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BU of 5w2f by Molmil
Crystal Structure of the C-terminal Domain of Human eIF2D at 1.4 A resolution
Descriptor: Eukaryotic translation initiation factor 2D, FORMIC ACID
Authors:Vaidya, A.T, Lomakin, I.B, Joseph, N.N, Dmitriev, S.E, Steitz, T.A.
Deposit date:2017-06-06
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of the C-terminal Domain of Human eIF2D and Its Implications on Eukaryotic Translation Initiation.
J. Mol. Biol., 429, 2017
5W2K
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BU of 5w2k by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-G34C) with hydroxymercuribenzoic acid guest structure
Descriptor: MERCURIBENZOIC ACID, Polyisoprenoid-binding protein, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-06
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5W2R
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BU of 5w2r by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-G34C) with 5-mercapto-2-nitrobenzoic acid guest structure
Descriptor: 5-MERCAPTO-2-NITRO-BENZOIC ACID, Polyisoprenoid-binding protein, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-06
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5VTL
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BU of 5vtl by Molmil
Structure of metacyclic invariant surface protein , Tb427.07.360, from Trypanosoma brucei.
Descriptor: Tb427.07.360- putative uncharacterized metacyclic invariant surface protein from Trypanosoma brucei
Authors:Ramswamy, R, Workman, S.D, Boulanger, M.J.
Deposit date:2017-05-17
Release date:2018-08-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8231 Å)
Cite:Structure of Tb427.07.360, an insect stage antigen from Trypanosoma brucei.
to be published
3VT2
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BU of 3vt2 by Molmil
Crystal structure of Ct1,3Gal43A in complex with isopropy-beta-D-thiogalactoside
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, GLYCEROL, Ricin B lectin
Authors:Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C.
Deposit date:2012-05-18
Release date:2012-12-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum
J.Struct.Biol., 180, 2012
5W2X
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BU of 5w2x by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N48C) for nanotechnology applications
Descriptor: Polyisoprenoid-binding protein, SULFATE ION, UNKNOWN LIGAND
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
5W31
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BU of 5w31 by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N48C) with mercuribenzoic acid guest structure
Descriptor: MERCURIBENZOIC ACID, Putative periplasmic protein, SULFATE ION, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
3VT1
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BU of 3vt1 by Molmil
Crystal structure of Ct1,3Gal43A in complex with galactose
Descriptor: Ricin B lectin, beta-D-galactopyranose
Authors:Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C.
Deposit date:2012-05-18
Release date:2012-12-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum
J.Struct.Biol., 180, 2012
5W3B
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BU of 5w3b by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N182C) with mercuribenzoic acid guest structure
Descriptor: EICOSANE, MERCURIBENZOIC ACID, Polyisoprenoid-binding protein, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018
1VEN
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BU of 1ven by Molmil
Crystal Structure Analysis of Y164E/maltose of Bacilus cereus Beta-amylase at pH 4.6
Descriptor: Beta-amylase, CALCIUM ION, alpha-D-glucopyranose
Authors:Hirata, A, Adachi, M, Utsumi, S, Mikami, B.
Deposit date:2004-04-03
Release date:2005-05-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type
Biochemistry, 43, 2004
5VVJ
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BU of 5vvj by Molmil
Cas1-Cas2 bound to half-site intermediate
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (112-MER), ...
Authors:Wright, A.V, Knott, G.J, Doxzen, K.W, Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5W4R
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BU of 5w4r by Molmil
Structure of RORgt bound to a tertiary alcohol
Descriptor: 1-{4-[(R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]piperidin-1-yl}ethan-1-one, Nuclear receptor ROR-gamma
Authors:Spurlino, J.
Deposit date:2017-06-12
Release date:2017-12-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:6-Substituted quinolines as ROR gamma t inverse agonists.
Bioorg. Med. Chem. Lett., 27, 2017
5W5B
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BU of 5w5b by Molmil
Crystal structure of Mycobacterium tuberculosis CRP-FNR family transcription factor Cmr (Rv1675c), truncated construct
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator Cmr
Authors:Cheung, J, Cassidy, M, Ginter, C, Ranganathan, S, Pata, D.J, McDonough, K.A.
Deposit date:2017-06-14
Release date:2017-12-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel structural features drive DNA binding properties of Cmr, a CRP family protein in TB complex mycobacteria.
Nucleic Acids Res., 46, 2018
5W5G
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BU of 5w5g by Molmil
Structure of Human Sts-1 histidine phosphatase domain
Descriptor: Ubiquitin-associated and SH3 domain-containing protein B
Authors:Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B.
Deposit date:2017-06-15
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2.
Biochemistry, 56, 2017
5VZO
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BU of 5vzo by Molmil
Sperm whale myoglobin H64A with nitric oxide
Descriptor: GLYCEROL, Myoglobin, NITRIC OXIDE, ...
Authors:Wang, B, Thomas, L.M, Richter-Addo, G.B.
Deposit date:2017-05-29
Release date:2018-06-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred Fe -NO Ligand Orientations in Myoglobin Distal Pockets.
Biochemistry, 57, 2018
5W6K
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BU of 5w6k by Molmil
Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P
Descriptor: (1R)-1-[6-amino-5-(dihydroxyamino)-2-hydroxypyridin-3-yl]-1,4-anhydro-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-erythro-pentitol, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-06-16
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.339 Å)
Cite:Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.
Nucleic Acids Res., 46, 2018
5VZU
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BU of 5vzu by Molmil
Crystal structure of the Skp1-FBXO31-cyclin D1 complex
Descriptor: Cyclin D1, F-box only protein 31, PHOSPHATE ION, ...
Authors:Li, Y, Jin, K, Hao, B.
Deposit date:2017-05-29
Release date:2018-01-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W0G
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BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5W1N
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BU of 5w1n by Molmil
Crystal structure of the human astrovirus 2 Oxford serotype capsid protein spike at 1.35-A resolution
Descriptor: Capsid polyprotein VP90
Authors:Bogdanoff, W.A, Perez, E.I, DuBois, R.M.
Deposit date:2017-06-04
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.348 Å)
Cite:Structural Basis for Escape of Human Astrovirus from Antibody Neutralization: Broad Implications for Rational Vaccine Design.
J. Virol., 92, 2018
1VGO
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BU of 1vgo by Molmil
Crystal Structure of Archaerhodopsin-2
Descriptor: Archaerhodopsin 2, RETINAL, SULFATE ION, ...
Authors:Yoshimura, K, Enami, N, Murakami, M, Okumura, H, Ihara, K, Kouyama, T.
Deposit date:2004-04-28
Release date:2005-10-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of archaerhodopsin-1 and -2: Common structural motif in archaeal light-driven proton pumps
J.Mol.Biol., 358, 2006
5W24
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BU of 5w24 by Molmil
Crystal Structure of 5C4 Fab
Descriptor: (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain
Authors:Battles, M.B, McLellan, J.S, Taher, N.M.
Deposit date:2017-06-05
Release date:2017-12-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
1VPD
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BU of 1vpd by Molmil
X-Ray Crystal Structure of Tartronate Semialdehyde Reductase [Salmonella Typhimurium LT2]
Descriptor: CHLORIDE ION, L(+)-TARTARIC ACID, TARTRONATE SEMIALDEHYDE REDUCTASE
Authors:Osipiuk, J, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-10-22
Release date:2004-10-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.
J Struct Funct Genomics, 10, 2009

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