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6JVB
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BU of 6jvb by Molmil
Crystal Structure of Human CRMP2 1-532, AGE-modified
Descriptor: Dihydropyrimidinase-related protein 2
Authors:Jiang, X, Ogawa, T, Hirokawa, N.
Deposit date:2019-04-16
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis.
Life Sci Alliance, 2, 2019
6HFI
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BU of 6hfi by Molmil
Human dihydroorotase mutant F1563A apo structure
Descriptor: CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45994723 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFL
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BU of 6hfl by Molmil
Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HG1
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BU of 6hg1 by Molmil
Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state
Descriptor: CAD protein,Dihydroorotase,CAD protein, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Del Cano-Ochoa, F.
Deposit date:2018-08-22
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFJ
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BU of 6hfj by Molmil
Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6HFS
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BU of 6hfs by Molmil
Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5
Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Grande Garcia, A.
Deposit date:2018-08-21
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.34904516 Å)
Cite:Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293, 2018
6JV9
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BU of 6jv9 by Molmil
Crystal Structure of Human CRMP2 1-532, unmodified
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydropyrimidinase-related protein 2, ...
Authors:Jiang, X, Ogawa, T, Hirokawa, N.
Deposit date:2019-04-16
Release date:2019-10-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis.
Life Sci Alliance, 2, 2019
6KLK
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BU of 6klk by Molmil
Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU
Descriptor: 5-FLUOROURACIL, D-hydantoinase/dihydropyrimidinase, ZINC ION
Authors:Huang, Y.H, Chen, I.C, Huang, C.Y.
Deposit date:2019-07-30
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.759 Å)
Cite:Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil.
Biochem.Biophys.Res.Commun., 519, 2019
4C6P
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BU of 4c6p by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0
Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6I
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BU of 4c6i by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.0
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-01-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C65
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BU of 4c65 by Molmil
Crystal structure of A. niger ochratoxinase
Descriptor: OCHRATOXINASE
Authors:Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
Deposit date:2013-09-17
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C5Z
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BU of 4c5z by Molmil
Crystal structure of A. niger ochratoxinase
Descriptor: OCHRATOXINASE
Authors:Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
Deposit date:2013-09-17
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C5Y
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BU of 4c5y by Molmil
Crystal structure of A. niger ochratoxinase
Descriptor: OCHRATOXINASE, ZINC ION
Authors:Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
Deposit date:2013-09-17
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C6E
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BU of 4c6e by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 5.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.263 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4BY3
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BU of 4by3 by Molmil
Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli.
Descriptor: DIHYDROOROTASE, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-07-17
Release date:2014-05-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6Q
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BU of 4c6q by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant bound to substrate at pH 7.0
Descriptor: CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.659 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4CNU
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BU of 4cnu by Molmil
CRYSTAL STRUCTURE OF WT HUMAN CRMP-4 from lattice translocation
Descriptor: DIHYDROPYRIMIDINASE-LIKE 3
Authors:Ponnusamy, R, Lebedev, A, Lohkamp, B.
Deposit date:2014-01-24
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Acta Crystallogr.,Sect.D, 70, 2014
4CNS
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BU of 4cns by Molmil
Crystal structure of truncated human CRMP-4
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Ponnusamy, R, Lohkamp, B.
Deposit date:2014-01-24
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Acta Crystallogr.,Sect.D, 70, 2014
4C6O
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BU of 4c6o by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 6.0
Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6L
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BU of 4c6l by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0
Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4B3Z
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BU of 4b3z by Molmil
Structure of the human collapsin response mediator protein-1, a lung cancer suppressor
Descriptor: DIHYDROPYRIMIDINASE-RELATED PROTEIN 1
Authors:Liu, S.H, Lin, Y.H, Huang, S.F, Niou, Y.K, Huang, L.L, Chen, Y.J.
Deposit date:2012-07-27
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of Human Collapsin Response Mediator Protein 1: A Possible Role of its C-Terminal Tail.
Acta Crystallogr.,Sect.F, 71, 2015
4C6N
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BU of 4c6n by Molmil
Crystal structure of the dihydroorotase domain of human CAD E1637T mutant bound to substrate at pH 6.0
Descriptor: CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6F
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BU of 4c6f by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5
Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ...
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.261 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6B
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BU of 4c6b by Molmil
Crystal structure of the dihydroorotase domain of human CAD with incomplete active site, obtained recombinantly from E. coli.
Descriptor: CAD PROTEIN, FORMIC ACID, GLYCEROL
Authors:Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
Deposit date:2013-09-18
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.656 Å)
Cite:Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4B90
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BU of 4b90 by Molmil
Crystal structure of WT human CRMP-5
Descriptor: 1,2-ETHANEDIOL, DIHYDROPYRIMIDINASE-RELATED PROTEIN 5
Authors:Ponnusamy, R, Lohkamp, B.
Deposit date:2012-08-31
Release date:2013-02-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights Into the Oligomerization of Crmps: Crystal Structure of Human Collapsin Response Mediator Protein 5.
J.Neurochem., 125, 2013

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