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6S83
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BU of 6s83 by Molmil
Crystal structure of methionine adenosyltransferase from Pyrococcus furiosus in complex with AMPPCP, SAM, and PCP
Descriptor: MAGNESIUM ION, METHYLENEDIPHOSPHONIC ACID, PHOSPHATE ION, ...
Authors:Degano, M, Minici, C, Porcelli, M.
Deposit date:2019-07-08
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.336 Å)
Cite:Structures of catalytic cycle intermediates of the Pyrococcus furiosus methionine adenosyltransferase demonstrate negative cooperativity in the archaeal orthologues.
J.Struct.Biol., 210, 2020
3QAV
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BU of 3qav by Molmil
Crystal structure of a glutathione S-transferase from Antarctic clam Laternula elliptica
Descriptor: Rho-class glutathione S-transferase
Authors:Park, A.K, Moon, J.H, Chi, Y.M.
Deposit date:2011-01-12
Release date:2012-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of a shellfish specific GST class glutathione S-transferase from antarctic bivalve Laternula elliptica reveals novel active site architecture.
Proteins, 81, 2013
3QC6
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BU of 3qc6 by Molmil
GspB
Descriptor: CALCIUM ION, GLYCEROL, NITROGEN MOLECULE, ...
Authors:Pyburn, T.M.
Deposit date:2011-01-15
Release date:2011-08-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors.
Plos Pathog., 7, 2011
3QCF
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BU of 3qcf by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization
Descriptor: 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QGH
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BU of 3qgh by Molmil
Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
Descriptor: N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase
Authors:Sheriff, S.
Deposit date:2011-01-24
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3QH9
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BU of 3qh9 by Molmil
Human Liprin-beta2 Coiled-Coil
Descriptor: AMMONIUM ION, GLYCEROL, IODIDE ION, ...
Authors:Stafford, R.L, Tang, M, Phillips, M.L, Bowie, J.U.
Deposit date:2011-01-25
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of the central coiled-coil domain from human liprin-beta2
Biochemistry, 50, 2011
3QCG
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BU of 3qcg by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid
Descriptor: 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, ACETIC ACID, Receptor-type tyrosine-protein phosphatase gamma
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
6RU1
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BU of 6ru1 by Molmil
Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid Um4X
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ...
Authors:Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S.
Deposit date:2019-05-27
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020
3QD2
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BU of 3qd2 by Molmil
Crystal structure of mouse PERK kinase domain
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Wenjun, C, Jingzhi, L, David, R, Bingdong, S.
Deposit date:2011-01-17
Release date:2011-04-27
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The structure of the PERK kinase domain suggests the mechanism for its activation.
Acta Crystallogr.,Sect.D, 67, 2011
8BL1
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BU of 8bl1 by Molmil
Human Sirt6 in complex with the inhibitor S6039 and ADP-ribose
Descriptor: 2-azanyl-5-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonyl-benzenesulfonamide, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:You, W, Steegborn, C.
Deposit date:2022-11-09
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen
To Be Published
3QGI
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BU of 3qgi by Molmil
Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-[(2S)-butan-2-yl]-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
Descriptor: GLYCEROL, N-[(2S)-butan-2-yl]-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, RNA-directed RNA polymerase
Authors:Sheriff, S.
Deposit date:2011-01-24
Release date:2011-04-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
8SNB
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BU of 8snb by Molmil
atomic model of sea urchin sperm doublet microtubule (48-nm periodicity)
Descriptor: ATP6V1FNB, C20Orf85, C4orf45, ...
Authors:Zeng, J, Zhang, R.
Deposit date:2023-04-26
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural specializations of the sperm tail.
Cell, 2023
6S5P
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BU of 6s5p by Molmil
Cfucosylated peptide SBL2 bound to Fucose binding Lectin LecB (PA-IIL) from Pseudomonas aeruginosa at 1.46 Angstrom resolution
Descriptor: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin, ...
Authors:Baeriswyl, S, Stocker, A, Reymond, J.-L.
Deposit date:2019-07-02
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
3QCC
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BU of 3qcc by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, orthorhombic crystal form
Descriptor: Receptor-type tyrosine-protein phosphatase gamma, VANADATE ION
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
8SBE
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BU of 8sbe by Molmil
Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM
Descriptor: Vesicular glutamate transporter 2
Authors:Li, F, Finer-Moore, J, Eriksen, J, Cheng, Y, Edwards, R, Stroud, R.
Deposit date:2023-04-03
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science, 368, 2020
3QCH
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BU of 3qch by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]-N-(methylsulfonyl)thiophene-2-carboxamide
Descriptor: 3-[(3,4-dichlorobenzyl)sulfanyl]-N-(methylsulfonyl)thiophene-2-carboxamide, Receptor-type tyrosine-protein phosphatase gamma
Authors:Sheriff, S.
Deposit date:2011-01-16
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
8SGX
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BU of 8sgx by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (10.3 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
7PPP
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BU of 7ppp by Molmil
Crystal structure of ZAD-domain of ZNF_276 protein from rabbit.
Descriptor: ZINC ION, Zinc finger protein 276
Authors:Boyko, K.M, Bonchuk, A.N, Nikolaeva, A.Y, Georgiev, P.G, Popov, V.O.
Deposit date:2021-09-14
Release date:2021-12-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity.
Structure, 30, 2022
7POH
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BU of 7poh by Molmil
Crystal structure of ZAD-domain of Serendipity-d protein from D.melanogaster
Descriptor: Serendipity locus protein delta, ZINC ION
Authors:Boyko, K.M, Kachalova, G.S, Bonchuk, A.N, Nikolaeva, A.Y, Georgiev, P.G, Popov, V.O.
Deposit date:2021-09-09
Release date:2021-12-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity.
Structure, 30, 2022
3QF6
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BU of 3qf6 by Molmil
Neutron structure of type-III Antifreeze Protein allows the reconstruction of AFP-ice interface
Descriptor: Type-3 ice-structuring protein HPLC 12
Authors:Howard, E.I, Blakeley, M.P, Haertlein, M, Petit-Haertlein, I, Mitschler, A, Fisher, S.J, Cousido-Siah, A, Salvay, A.G, Popov, A, Muller-Dieckmann, C, Petrova, T, Podjarny, A.
Deposit date:2011-01-21
Release date:2011-06-22
Last modified:2024-03-20
Method:NEUTRON DIFFRACTION (1.85 Å)
Cite:Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface.
J.Mol.Recognit., 24, 2011
8SGY
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BU of 8sgy by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (8.62 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SER
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BU of 8ser by Molmil
Cryo-EM Structure of RyR1 + Adenosine
Descriptor: ADENOSINE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEP
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BU of 8sep by Molmil
Cryo-EM Structure of RyR1 + ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
8SEQ
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BU of 8seq by Molmil
Cryo-EM Structure of RyR1 + AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
3S8V
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BU of 3s8v by Molmil
Crystal structure of LRP6-Dkk1 complex
Descriptor: Dickkopf-related protein 1, Low-density lipoprotein receptor-related protein 6
Authors:Cheng, Z, Xu, W.
Deposit date:2011-05-31
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
Nat.Struct.Mol.Biol., 18, 2011

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