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6BUW
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BU of 6buw by Molmil
Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-11
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6OSQ
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BU of 6osq by Molmil
RF1 accommodated state bound Release complex 70S at long incubation time point
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-26
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-25
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
5JUP
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BU of 5jup by Molmil
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A.
Deposit date:2016-05-10
Release date:2016-10-05
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
6QNQ
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BU of 6qnq by Molmil
70S ribosome initiation complex (IC) with experimentally assigned potassium ions
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2019-02-11
Release date:2019-06-19
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019
8BTK
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BU of 8btk by Molmil
Structure of the TRAP complex with the Sec translocon and a translating ribosome
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N.
Deposit date:2022-11-29
Release date:2023-05-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis of the TRAP complex function in ER protein biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
8UER
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BU of 8uer by Molmil
In-situ complex I with Q10 (State-gamma)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
Authors:Zheng, W, Zhu, J, Zhang, K.
Deposit date:2023-10-02
Release date:2024-06-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
4TUE
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BU of 4tue by Molmil
Crystal structure of ASL-SufJ bound to Codon ACC-U on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
7JT2
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BU of 7jt2 by Molmil
70S ribosome stalled on long mRNA with ArfB bound in the A site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2020-08-16
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:ArfB can displace mRNA to rescue stalled ribosomes
Nat Commun, 11, 2020
8SV1
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BU of 8sv1 by Molmil
Caspase-1 complex with interleukin-18
Descriptor: Caspase-1, Interleukin-18
Authors:Dong, Y, Pascal, D, Jon, K, Wu, H.
Deposit date:2023-05-15
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Caspase-1 complex with interleukin-18
To Be Published
7AS9
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BU of 7as9 by Molmil
Bacillus subtilis ribosome-associated quality control complex state A. Ribosomal 50S subunit with peptidyl tRNA in the A/P position and RqcH.
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.
Mol.Cell, 81, 2021
5LZE
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BU of 5lze by Molmil
Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
Deposit date:2016-09-29
Release date:2016-11-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
1RHZ
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BU of 1rhz by Molmil
The structure of a protein conducting channel
Descriptor: Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta
Authors:van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A.
Deposit date:2003-11-15
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of a protein-conducting channel.
Nature, 427, 2004
1XBP
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BU of 1xbp by Molmil
Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ...
Authors:Schluenzen, F, Pyetan, E, Fucini, P, Yonath, A, Harms, J.M.
Deposit date:2004-08-31
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Mol.Microbiol., 54, 2004
5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
7K51
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BU of 7k51 by Molmil
Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
6BU8
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BU of 6bu8 by Molmil
70S ribosome with S1 domains 1 and 2 (Class 1)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2017-12-08
Release date:2018-01-31
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM.
Methods, 137, 2018
5TGM
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BU of 5tgm by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
Authors:Melnikov, S, Mailliot, J, Yusupov, M.
Deposit date:2016-09-28
Release date:2017-01-18
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
1HKG
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BU of 1hkg by Molmil
STRUCTURAL DYNAMICS OF YEAST HEXOKINASE DURING CATALYSIS
Descriptor: HEXOKINASE A
Authors:Bennett Jr, W.S, Steitz, T.A.
Deposit date:1980-12-22
Release date:1981-02-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural dynamics of yeast hexokinase during catalysis.
Philos.Trans.R.Soc.London,Ser.B, 293, 1981
5U4I
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BU of 5u4i by Molmil
Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
3J7O
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BU of 3j7o by Molmil
Structure of the mammalian 60S ribosomal subunit
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
6Q8X
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BU of 6q8x by Molmil
Respiratory complex I from Thermus thermophilus with bound Pyridaben.
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ...
Authors:Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A.
Deposit date:2018-12-16
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
1GZV
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BU of 1gzv by Molmil
The crystal structure of phosphoglucose isomerase from pig muscle complexed with 5-phosphoarabinonate
Descriptor: 5-PHOSPHOARABINONIC ACID, GLUCOSE-6-PHOSPHATE ISOMERASE
Authors:Davies, C, Muirhead, H.
Deposit date:2002-06-06
Release date:2002-10-31
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Crystal Structure of Phosphoglucose Isomerase from Pig Muscle and its Complex with 5-Phosphoarabinonate
Proteins: Struct.,Funct., Genet., 49, 2002
3B0V
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BU of 3b0v by Molmil
tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA
Descriptor: FLAVIN MONONUCLEOTIDE, tRNA, tRNA-dihydrouridine synthase
Authors:Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I.
Deposit date:2011-06-14
Release date:2011-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Molecular basis of dihydrouridine formation on tRNA
Proc.Natl.Acad.Sci.USA, 108, 2011
4V8P
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BU of 4v8p by Molmil
T.thermophila 60S ribosomal subunit in complex with initiation factor 6.
Descriptor: 26S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N.
Deposit date:2011-09-14
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6.
Science, 334, 2011

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