2VMX
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![BU of 2vmx by Molmil](/molmil-images/mine/2vmx) | Crystal structure of F351GbsSHMT in complex with L-allo-Thr | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ALLO-THREONINE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2008-01-29 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding. Biochem.J., 418, 2009
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3IN5
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![BU of 3in5 by Molmil](/molmil-images/mine/3in5) | Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*CP*TP*AP*(8OG)P*GP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*G*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*(DOC))-3'), ... | Authors: | Silverstein, T.D, Vasquez-Del Carpio, R, Aggarwal, A.K. | Deposit date: | 2009-08-11 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion PLOS ONE, 4, 2009
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4V3Q
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![BU of 4v3q by Molmil](/molmil-images/mine/4v3q) | Designed armadillo repeat protein with 4 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | Descriptor: | CALCIUM ION, GLYCEROL, YIII_M4_AII | Authors: | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | Deposit date: | 2014-10-20 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects. Acta Crystallogr D Struct Biol, 72, 2016
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2VMQ
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![BU of 2vmq by Molmil](/molmil-images/mine/2vmq) | Structure of N341AbsSHMT crystallized in the presence of L-allo-Thr | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2008-01-29 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding. Biochem.J., 418, 2009
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5UA3
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![BU of 5ua3 by Molmil](/molmil-images/mine/5ua3) | Crystal Structure of a DNA G-Quadruplex with a Cytosine Bulge | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*TP*GP*CP*GP*GP*AP*GP*GP*GP*TP*GP*GP*GP*CP*CP*T)-3'), POTASSIUM ION | Authors: | Meier, M, McDougall, M.D, Krahn, N.J, Moya-Torres, A, McRae, E.K.S, Booy, E.P, Patel, T.R, McKenna, S.A, Stetefeld, J. | Deposit date: | 2016-12-18 | Release date: | 2017-11-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8802 Å) | Cite: | Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge. Nucleic Acids Res., 46, 2018
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5Z1G
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![BU of 5z1g by Molmil](/molmil-images/mine/5z1g) | Structure of the Brx1 and Ebp2 complex | Descriptor: | Ribosome biogenesis protein BRX1, SULFATE ION, rRNA-processing protein EBP2 | Authors: | Zheng, S, Ye, K. | Deposit date: | 2017-12-26 | Release date: | 2018-04-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.294 Å) | Cite: | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate Protein Cell, 10, 2019
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2VMZ
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![BU of 2vmz by Molmil](/molmil-images/mine/2vmz) | Crystal structure of F351GbsSHMT in complex with Gly | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2008-01-29 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding. Biochem.J., 418, 2009
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3BEP
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![BU of 3bep by Molmil](/molmil-images/mine/3bep) | Structure of a sliding clamp on DNA | Descriptor: | 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ... | Authors: | Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structure of a sliding clamp on DNA Cell(Cambridge,Mass.), 132, 2008
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5ZLC
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![BU of 5zlc by Molmil](/molmil-images/mine/5zlc) | Binary complex of human DNA Polymerase Mu with MndGTP | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-03-27 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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2OGH
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![BU of 2ogh by Molmil](/molmil-images/mine/2ogh) | Solution structure of yeast eIF1 | Descriptor: | Eukaryotic translation initiation factor eIF-1 | Authors: | Reibarkh, M, del Rio, F, Yamamoto, Y, Asano, K, Wagner, G. | Deposit date: | 2007-01-05 | Release date: | 2007-11-20 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Eukaryotic Initiation Factor (eIF) 1 Carries Two Distinct eIF5-binding Faces Important for Multifactor Assembly and AUG Selection. J.Biol.Chem., 283, 2008
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2VMS
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![BU of 2vms by Molmil](/molmil-images/mine/2vms) | Crystal structure of Y60AbsSHMT crystallized in the presence of Glycine | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2008-01-29 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding. Biochem.J., 418, 2009
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2VMU
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![BU of 2vmu by Molmil](/molmil-images/mine/2vmu) | Crystal structure of Y60AbsSHMT crystallized in the presence of L- allo-Thr | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... | Authors: | Rajaram, V, Pai, V.R, Bisht, S, Bhavani, B.S, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2008-01-29 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural and Functional Studies of Bacillus Stearothermophilus Serine Hydroxymethyltransferase: The Role of Asn(341), Tyr(60) and Phe(351) in Tetrahydrofolate Binding. Biochem.J., 418, 2009
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3LOB
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![BU of 3lob by Molmil](/molmil-images/mine/3lob) | Crystal Structure of Flock House Virus calcium mutant | Descriptor: | Coat protein beta, Coat protein gamma, RNA (5'-R(*UP*UP*U*AP*UP*CP*UP*(P))-3'), ... | Authors: | Johnson, J.E, Banerjee, M, Speir, J.A, Huang, R. | Deposit date: | 2010-02-03 | Release date: | 2010-04-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure and function of a genetically engineered mimic of a nonenveloped virus entry intermediate. J.Virol., 84, 2010
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6AK5
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![BU of 6ak5 by Molmil](/molmil-images/mine/6ak5) | Binary Complex of Human DNA Polymerase Mu with MnGTP | Descriptor: | DNA-directed DNA/RNA polymerase mu, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Chang, Y.K, Wu, W.J, Tsai, M.D. | Deposit date: | 2018-08-30 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
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4GLA
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![BU of 4gla by Molmil](/molmil-images/mine/4gla) | OBody NL8 bound to hen egg-white lysozyme | Descriptor: | Lysozyme C, OBody NL8 | Authors: | Steemson, J.D. | Deposit date: | 2012-08-14 | Release date: | 2013-08-14 | Last modified: | 2014-02-12 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold. Plos One, 9, 2014
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2VY4
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![BU of 2vy4 by Molmil](/molmil-images/mine/2vy4) | U11-48K CHHC ZN-FINGER DOMAIN | Descriptor: | U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION | Authors: | Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R. | Deposit date: | 2008-07-17 | Release date: | 2009-02-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009
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2J4K
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![BU of 2j4k by Molmil](/molmil-images/mine/2j4k) | Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP to 2.2 Angstrom resolution | Descriptor: | CADMIUM ION, MAGNESIUM ION, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Jensen, K.S, Johansson, E, Jensen, K.F. | Deposit date: | 2006-09-01 | Release date: | 2007-02-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
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7SV2
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![BU of 7sv2 by Molmil](/molmil-images/mine/7sv2) | Human Cytochrome P450 (CYP) 3A5 ternary complex with azamulin | Descriptor: | (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl [(5-amino-1H-1,2,4-triazol-3-yl)sulfanyl]acetate, Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hsu, M, Johnson, E.F. | Deposit date: | 2021-11-18 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structural characterization of the homotropic cooperative binding of azamulin to human cytochrome P450 3A5. J.Biol.Chem., 298, 2022
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6Y0Y
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![BU of 6y0y by Molmil](/molmil-images/mine/6y0y) | Sarcin Ricin Loop, mutant C2666U | Descriptor: | MAGNESIUM ION, RNA (27-MER), SODIUM ION | Authors: | Ennifar, E, Westhof, E. | Deposit date: | 2020-02-10 | Release date: | 2021-02-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Sarcin Ricin Loop, mutant C2666U To Be Published
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6Y0T
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![BU of 6y0t by Molmil](/molmil-images/mine/6y0t) | |
8G66
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![BU of 8g66 by Molmil](/molmil-images/mine/8g66) | Structure with SJ3149 | Descriptor: | (3S)-3-{5-[(1,2-benzoxazol-3-yl)amino]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}piperidine-2,6-dione, Casein kinase I isoform alpha, DNA damage-binding protein 1, ... | Authors: | Miller, D.J, Young, S.M, Fischer, M. | Deposit date: | 2023-02-14 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Structure of ternary complex with molecular glue targeting CK1A for degradation by the CRL4CRBN ubiquitin ligase To Be Published
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2N0Y
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![BU of 2n0y by Molmil](/molmil-images/mine/2n0y) | NMR structure of the complex between the C-terminal domain of the Rift Valley fever virus protein NSs and the PH domain of the Tfb1 subunit of TFIIH | Descriptor: | Non-structural protein NS-S, RNA polymerase II transcription factor B subunit 1 | Authors: | Cyr, N, de la Fuente, C, Lecoq, L, Guendel, I, Chabot, P.R, Kehn-Hall, K, Omichinski, J.G. | Deposit date: | 2015-03-18 | Release date: | 2015-04-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A Omega XaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence. Proc.Natl.Acad.Sci.USA, 112, 2015
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5Z20
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![BU of 5z20 by Molmil](/molmil-images/mine/5z20) | The ternary structure of D-lactate dehydrogenase from Pseudomonas aeruginosa with NADH and oxamate | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-lactate dehydrogenase (Fermentative), DI(HYDROXYETHYL)ETHER, ... | Authors: | Furukawa, N, Miyanaga, A, Nakajima, M, Taguchi, H. | Deposit date: | 2017-12-28 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis of Sequential Allosteric Transitions in Tetrameric d-Lactate Dehydrogenases from Three Gram-Negative Bacteria. Biochemistry, 57, 2018
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3B4A
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![BU of 3b4a by Molmil](/molmil-images/mine/3b4a) | |
2XKV
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![BU of 2xkv by Molmil](/molmil-images/mine/2xkv) | Atomic Model of the SRP-FtsY Early Conformation | Descriptor: | 4.5S RNA, CELL DIVISION PROTEIN FTSY, SIGNAL RECOGNITION PARTICLE PROTEIN | Authors: | Estrozi, L.F, Boehringer, D, Shan, S.-o, Ban, N, Schaffitzel, C. | Deposit date: | 2010-07-13 | Release date: | 2010-12-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Cryo-Em Structure of the E. Coli Translating Ribosome in Complex with Srp and its Receptor. Nat.Struct.Mol.Biol., 18, 2011
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