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6I7T
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eIF2B:eIF2 complex
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Adomavicius, T, Guaita, M, Roseman, A.M, Pavitt, G.D.
Deposit date:2018-11-17
Release date:2019-05-22
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.61 Å)
Cite:The structural basis of translational control by eIF2 phosphorylation.
Nat Commun, 10, 2019
5NVK
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Crystal structure of the human 4EHP-GIGYF1 complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 1
Authors:Peter, D, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVL
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Crystal structure of the human 4EHP-GIGYF2 complex
Descriptor: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 2
Authors:Peter, D, Valkov, E.
Deposit date:2017-05-04
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5WPJ
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BU of 5wpj by Molmil
Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to NADPH in open conformations
Descriptor: 3-hydroxy-3-methylglutaryl coenzyme A reductase, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Miller, B.R, Kung, Y.
Deposit date:2017-08-04
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Features and Domain Movements Controlling Substrate Binding and Cofactor Specificity in Class II HMG-CoA Reductase.
Biochemistry, 57, 2018
3WBK
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BU of 3wbk by Molmil
crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex
Descriptor: Eukaryotic translation initiation factor 1A, Eukaryotic translation initiation factor 5B
Authors:Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M.
Deposit date:2013-05-20
Release date:2014-11-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A
Acta Crystallogr.,Sect.D, 70, 2014
6HB3
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BU of 6hb3 by Molmil
Structure of Hgh1, crystal form II
Descriptor: Protein HGH1
Authors:Moenkemeyer, L, Klaips, C.L, Balchin, D, Koerner, R, Hartl, F.U, Bracher, A.
Deposit date:2018-08-09
Release date:2019-02-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2.
Mol.Cell, 74, 2019
6HB1
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Structure of Hgh1, crystal form I
Descriptor: CHLORIDE ION, Protein HGH1
Authors:Moenkemeyer, L, Klaips, C.L, Balchin, D, Koerner, R, Hartl, F.U, Bracher, A.
Deposit date:2018-08-09
Release date:2019-02-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2.
Mol.Cell, 74, 2019
6HB2
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BU of 6hb2 by Molmil
Structure of Hgh1, crystal form I, Selenomethionine derivative
Descriptor: CHLORIDE ION, Protein HGH1
Authors:Moenkemeyer, L, Klaips, C.L, Balchin, D, Koerner, R, Hartl, F.U, Bracher, A.
Deposit date:2018-08-09
Release date:2019-02-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2.
Mol.Cell, 74, 2019
3J9V
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BU of 3j9v by Molmil
Yeast V-ATPase state 3
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
3J9U
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Yeast V-ATPase state 2
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
3J9T
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BU of 3j9t by Molmil
Yeast V-ATPase state 1
Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J, Benlekbir, S, Rubinstein, J.L.
Deposit date:2015-02-23
Release date:2015-05-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
4YNW
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BU of 4ynw by Molmil
Assembly Chaperone of RpL4 (Acl4) (Residues 1-338)
Descriptor: ACL4
Authors:Huber, F.M, Hoelz, A.
Deposit date:2015-03-11
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension.
Mol.Cell, 58, 2015
4YNV
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Assembly Chaperone of RpL4 (Acl4) (Residues 28-338)
Descriptor: ACL4
Authors:Huber, F.M, Hoelz, A.
Deposit date:2015-03-11
Release date:2015-05-13
Last modified:2020-04-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension.
Mol.Cell, 58, 2015
6KC0
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BU of 6kc0 by Molmil
fused To-MtbCsm1 with 2ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION
Authors:Li, T, Huo, Y, Jiang, T.
Deposit date:2019-06-26
Release date:2020-07-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Int.J.Biol.Macromol., 170, 2020
3V86
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BU of 3v86 by Molmil
Computational Design of a Protein Crystal
Descriptor: De novo design helix
Authors:Acharya, R, North, B, Saven, J, DeGrado, W.
Deposit date:2011-12-22
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Computational design of a protein crystal.
Proc.Natl.Acad.Sci.USA, 109, 2012
4I99
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BU of 4i99 by Molmil
Crystal structure of the SmcHead bound to the C-winged helix domain of ScpA
Descriptor: Chromosome partition protein Smc, PHOSPHATE ION, Putative uncharacterized protein
Authors:Shin, H.C, Soh, Y.M, Oh, B.H.
Deposit date:2012-12-05
Release date:2013-01-30
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An asymmetric SMC-kleisin bridge in prokaryotic condensin.
Nat.Struct.Mol.Biol., 20, 2013
4NCL
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BU of 4ncl by Molmil
Crystal structure of eukaryotic translation initiation factor eIF5B (517-970) from Chaetomium thermophilum in complex with GDP
Descriptor: Eukaryotic translation initiation factor 5B-like protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kuhle, B, Ficner, R.
Deposit date:2013-10-24
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.115 Å)
Cite:eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
Embo J., 33, 2014
4I98
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BU of 4i98 by Molmil
Crystal structure of the complex between ScpA(residues 1-160)-ScpB(residues 1-183)
Descriptor: Segregation and condensation protein A, Segregation and condensation protein B
Authors:Shin, H.C, Oh, B.H.
Deposit date:2012-12-05
Release date:2013-01-30
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An asymmetric SMC-kleisin bridge in prokaryotic condensin
Nat.Struct.Mol.Biol., 20, 2013
3JPT
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BU of 3jpt by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro chloro methylene triphosphate
Descriptor: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPO
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BU of 3jpo by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochloromethylene triphosphate
Descriptor: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPQ
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BU of 3jpq by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monoBromo methylene triphosphate
Descriptor: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPN
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BU of 3jpn by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dichloro methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(S)-{[(R)-[dichloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPR
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BU of 3jpr by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dimethyl methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(1-methyl-1-phosphonoethyl)phosphoryl]oxy}phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPS
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BU of 3jps by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro methyl methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(S)-{[(S)-[(1R)-1-fluoro-1-phosphonoethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010
3JPP
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BU of 3jpp by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-MonoMethyl Methylene triphosphate
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy({(S)-hydroxy[(1R)-1-phosphonoethyl]phosphoryl}oxy)phosphoryl]guanosine, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Upton, J, Kashmerov, B, Beard, W.A, Wilson, S.H, Goodman, M.F, McKenna, C.E.
Deposit date:2009-09-04
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132, 2010

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