3KQ4
| Structure of Intrinsic Factor-Cobalamin bound to its receptor Cubilin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Andersen, C.B.F, Madsen, M, Moestrup, S.K, Andersen, G.R. | Deposit date: | 2009-11-17 | Release date: | 2010-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes. Nature, 464, 2010
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3KPZ
| Crystal structure of a novel vitamin D3 analogue, ZK203278 showing dissociated profile | Descriptor: | (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,5S)-5-hydroxy-1-methyl-5-(1,3-thiazol-2-yl)pentyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol, Vitamin D3 receptor | Authors: | Rochel, N, Moras, D. | Deposit date: | 2009-11-17 | Release date: | 2011-10-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile. Anticancer Res., 32, 2012
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2RDG
| Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with Sialyl Lewis X | Descriptor: | CITRIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, POTASSIUM ION, ... | Authors: | Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D. | Deposit date: | 2007-09-24 | Release date: | 2007-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition Mol.Microbiol., 66, 2007
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2R61
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6DR2
| Ca2+-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-07-18 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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3KZD
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6DQN
| Class 1 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQZ
| Class 4 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.01 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DA3
| Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2R)-1-oxo-3-phenyl-1-{[(pyridin-3-yl)methyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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6DA2
| Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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2QCB
| T7-tagged full-length streptavidin complexed with ruthenium ligand | Descriptor: | N-(4-{[(2-AMINOETHYL)AMINO]SULFONYL}PHENYL)-5-[(3AS,4S,6AR)-2-OXOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANAMIDE-(1,2,3,4,5,6-ETA)-BENZENE-CHLORO-RUTHENIUM(III), Streptavidin | Authors: | Le Trong, I, Creus, M, Pordea, A, Ward, T.R, Stenkamp, R.E. | Deposit date: | 2007-06-19 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | X-ray structure and designed evolution of an artificial transfer hydrogenase Angew.Chem.Int.Ed.Engl., 47, 2008
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6DA5
| Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2S)-1-oxo-3-phenyl-1-{[(pyridin-3-yl)methyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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6DAG
| Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2S)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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2QBX
| EphB2/SNEW Antagonistic Peptide Complex | Descriptor: | Ephrin type-B receptor 2, SULFATE ION, antagonistic peptide | Authors: | Chrencik, J.E, Brooun, A, Recht, M.I, Nicola, G, Pasquale, E.B, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | Deposit date: | 2007-06-18 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. J.Biol.Chem., 282, 2007
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6DA8
| Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[(pyridin-3-yl)methyl]-D-phenylalaninamide, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sevrioukova, I.F. | Deposit date: | 2018-05-01 | Release date: | 2019-04-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
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2R40
| Crystal structure of 20E bound EcR/USP | Descriptor: | (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, CITRATE ANION, Ecdysone Receptor, ... | Authors: | Moras, D, Billas, I.M.L, Browning, C. | Deposit date: | 2007-08-30 | Release date: | 2007-10-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor J.Biol.Chem., 282, 2007
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6DQV
| Class 2 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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8J9N
| Gq bound FZD1 in ligand-free state | Descriptor: | Frizzled-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Lin, X, Xu, F. | Deposit date: | 2023-05-04 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways. Cell Discov, 10, 2024
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3KGF
| The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan | Descriptor: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2009-10-29 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis J.Biol.Chem., 285, 2010
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2QKH
| Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP | Descriptor: | Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ... | Authors: | Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T. | Deposit date: | 2007-07-11 | Release date: | 2007-08-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor Proc.Natl.Acad.Sci.Usa, 104, 2007
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3C6Q
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4W5J
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3BRN
| Crystal Structure of AM182 Serotonin Complex | Descriptor: | Lipocalin, SEROTONIN | Authors: | Mans, B.J, Ribeiro, J.M, Andersen, J.F. | Deposit date: | 2007-12-21 | Release date: | 2008-04-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure, function, and evolution of biogenic amine-binding proteins in soft ticks. J.Biol.Chem., 283, 2008
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3BS2
| Crystal Structure of Monomine | Descriptor: | GLYCEROL, Lipocalin | Authors: | Mans, B.J, Ribeiro, J.M, Andersen, J.F. | Deposit date: | 2007-12-21 | Release date: | 2008-04-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structure, function, and evolution of biogenic amine-binding proteins in soft ticks. J.Biol.Chem., 283, 2008
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3D0X
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