2Q4Z
 
 | | Ensemble refinement of the protein crystal structure of an aspartoacylase from Rattus norvegicus | | Descriptor: | Aspartoacylase, SULFATE ION, ZINC ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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7SI6
 | | Structure of ATP7B in state 1 | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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7SI7
 | | Structure of ATP7B in state 2 | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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7SI3
 | | Consensus structure of ATP7B | | Descriptor: | MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION | | Authors: | Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P. | | Deposit date: | 2021-10-12 | | Release date: | 2022-03-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
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2GU2
 | | Crystal Structure of an Aspartoacylase from Rattus norvegicus | | Descriptor: | Aspa protein, SULFATE ION, ZINC ION | | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-04-28 | | Release date: | 2006-06-20 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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1BDB
 | | CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE FROM PSEUDOMONAS SP. LB400 | | Descriptor: | CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Huelsmeyer, M, Hecht, H.-J, Niefind, K, Hofer, B, Timmis, K.N, Schomburg, D. | | Deposit date: | 1997-05-10 | | Release date: | 1997-11-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from a PCB degrader at 2.0 A resolution.
Protein Sci., 7, 1998
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5WXZ
 | | Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with D-aspartate | | Descriptor: | D-ASPARTIC ACID, McyF | | Authors: | Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2017-01-09 | | Release date: | 2018-01-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF.
Biochem.Biophys.Res.Commun., 514, 2019
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2GWN
 | | The structure of putative dihydroorotase from Porphyromonas gingivalis. | | Descriptor: | BETA-MERCAPTOETHANOL, CACODYLATE ION, CHLORIDE ION, ... | | Authors: | Cuff, M.E, Borovilos, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-05-04 | | Release date: | 2006-06-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of putative dihydroorotase from Porphyromonas gingivalis.
To be Published
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2LQT
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2LQ8
 | | Domain interaction in Thermotoga maritima NusG | | Descriptor: | Transcription antitermination protein nusG | | Authors: | Droegemueller, J, Stegmann, C, Burmann, B, Roesch, P, Wahl, M.C, Schweimer, K. | | Deposit date: | 2012-02-27 | | Release date: | 2013-01-23 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | An Autoinhibited State in the Structure of Thermotoga maritima NusG.
Structure, 21, 2013
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2PG5
 | | Crystal Structure of Human Microsomal P450 2A6 N297Q | | Descriptor: | 1,2-ETHANEDIOL, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. | | Deposit date: | 2007-04-06 | | Release date: | 2007-07-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants.
Arch.Biochem.Biophys., 464, 2007
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2PFG
 | | Crystal structure of human CBR1 in complex with BiGF2. | | Descriptor: | (5R,10S)-5-{[(CARBOXYMETHYL)AMINO]CARBONYL}-7-OXO-3-THIA-1,6-DIAZABICYCLO[4.4.1]UNDECANE-10-CARBOXYLIC ACID, CHLORIDE ION, Carbonyl reductase [NADPH] 1, ... | | Authors: | Rauh, D, Bateman, R.L, Shokat, K.M. | | Deposit date: | 2007-04-04 | | Release date: | 2007-09-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Glutathione traps formaldehyde by formation of a bicyclo[4.4.1]undecane adduct.
Org.Biomol.Chem., 5, 2007
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5YZ5
 | | Crystal Structure of Human CRMP-2 with T509D-T514D-S518D-S522D mutations | | Descriptor: | Dihydropyrimidinase-related protein 2, SULFATE ION | | Authors: | Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R. | | Deposit date: | 2017-12-13 | | Release date: | 2018-03-21 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
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7BVP
 | | AdhE spirosome in extended conformation | | Descriptor: | Aldehyde-alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | | Authors: | Kim, G.J, Song, J.J. | | Deposit date: | 2020-04-11 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Aldehyde-alcohol dehydrogenase undergoes structural transition to form extended spirosomes for substrate channeling.
Commun Biol, 3, 2020
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5YZB
 | | Crystal Structure of Human CRMP-2 with S522D-T509D-T514D-S518D mutations crystallized with GSK3b | | Descriptor: | Dihydropyrimidinase-related protein 2 | | Authors: | Imasaki, T, Sumi, T, Aoki, M, Sakai, N, Nitta, E, Shirouzu, M, Nitta, R. | | Deposit date: | 2017-12-13 | | Release date: | 2018-03-21 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Insights into the Altering Function of CRMP2 by Phosphorylation.
Cell Struct. Funct., 43, 2018
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2HPM
 | | Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III | | Descriptor: | CHLORIDE ION, DNA Polymerase III alpha subunit, MAGNESIUM ION, ... | | Authors: | Bailey, S, Wing, R.A, Steitz, T.A. | | Deposit date: | 2006-07-17 | | Release date: | 2006-09-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006
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2HSN
 | | Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes | | Descriptor: | GU4 nucleic-binding protein 1, Methionyl-tRNA synthetase, cytoplasmic | | Authors: | Simader, H, Koehler, C, Basquin, J, Suck, D. | | Deposit date: | 2006-07-22 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes.
Nucleic Acids Res., 34, 2006
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6GDD
 | | DIHYDROOROTASE FROM AQUIFEX AEOLICUS UNDER 1200 BAR OF HYDROSTATIC PRESSURE | | Descriptor: | Dihydroorotase, SULFATE ION, ZINC ION | | Authors: | Prange, T, Girard, E, Herve, G, Evans, D.R. | | Deposit date: | 2018-04-23 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Pressure-induced activation of latent dihydroorotase from Aquifex aeolicus as revealed by high pressure protein crystallography.
Febs J., 286, 2019
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2Q6N
 | | Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole | | Descriptor: | 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Zhao, Y, Sun, L, Muralidhara, B.K, Kumar, S, White, M.A, Stout, C.D, Halpert, J.R. | | Deposit date: | 2007-06-05 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4.
Biochemistry, 46, 2007
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6G3Y
 | | Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH5675 | | Descriptor: | 4-(4-azanyl-2-oxidanylidene-3~{H}-benzimidazol-1-yl)-~{N}-(4-iodophenyl)piperidine-1-carboxamide, ACETATE ION, N-glycosylase/DNA lyase, ... | | Authors: | Masuyer, G, Helleday, T, Stenmark, P. | | Deposit date: | 2018-03-26 | | Release date: | 2018-11-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science, 362, 2018
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2Q09
 | | Crystal structure of Imidazolonepropionase from environmental sample with bound inhibitor 3-(2,5-Dioxo-imidazolidin-4-yl)-propionic acid | | Descriptor: | 3-[(4S)-2,5-DIOXOIMIDAZOLIDIN-4-YL]PROPANOIC ACID, FE (III) ION, Imidazolonepropionase | | Authors: | Tyagi, R, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2007-05-21 | | Release date: | 2007-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | A common catalytic mechanism for proteins of the HutI family.
Biochemistry, 47, 2008
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2Q51
 | | Ensemble refinement of the protein crystal structure of an aspartoacylase from Homo sapiens | | Descriptor: | Aspartoacylase, PHOSPHATE ION, ZINC ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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2HY6
 | | A seven-helix coiled coil | | Descriptor: | General control protein GCN4, HEXANE-1,6-DIOL | | Authors: | Liu, J, Zheng, Q, Deng, Y, Cheng, C.S, Kallenbach, N.R, Lu, M. | | Deposit date: | 2006-08-04 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | A seven-helix coiled coil.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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3ISV
 | | Crystal structure of glutamate racemase from Listeria monocytogenes in complex with acetate ion | | Descriptor: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Majorek, K.A, Chruszcz, M, Skarina, T, Onopriyenko, O, Stam, J, Anderson, W.F, Savchenko, A, Bujnicki, J.M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2009-08-27 | | Release date: | 2009-09-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of glutamate racemase from Listeria monocytogenes in complex with acetate ion
To be Published
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3IST
 | | Crystal structure of glutamate racemase from Listeria monocytogenes in complex with succinic acid | | Descriptor: | CHLORIDE ION, Glutamate racemase, SUCCINIC ACID | | Authors: | Majorek, K.A, Chruszcz, M, Skarina, T, Onopriyenko, O, Stam, J, Anderson, W.F, Savchenko, A, Bujnicki, J.M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2009-08-27 | | Release date: | 2009-09-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of glutamate racemase from Listeria monocytogenes in complex with succinic acid
TO BE PUBLISHED
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