6HZW
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![BU of 6hzw by Molmil](/molmil-images/mine/6hzw) | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL 2.22 resolution | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2018-10-24 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3MG1
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![BU of 3mg1 by Molmil](/molmil-images/mine/3mg1) | Crystal structure of the orange carotenoid protein from cyanobacteria Synechocystis sp. PCC 6803 | Descriptor: | GLYCEROL, Orange carotenoid protein, beta,beta-caroten-4-one | Authors: | Wilson, A, Kinney, J, Zwart, P.H, Punginelli, C, D'Haen, S, Perreau, F, Klein, M.G, Kirilovsky, D, Kerfeld, C.A. | Deposit date: | 2010-04-05 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Structural determinants underlying photoprotection in the photoactive orange carotenoid protein of cyanobacteria. J.Biol.Chem., 285, 2010
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1W4J
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![BU of 1w4j by Molmil](/molmil-images/mine/1w4j) | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | Descriptor: | PYRUVATE DEHYDROGENASE E2 | Authors: | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | Deposit date: | 2004-07-23 | Release date: | 2005-07-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family. J. Mol. Biol., 353, 2005
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3M2C
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![BU of 3m2c by Molmil](/molmil-images/mine/3m2c) | |
1VZE
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![BU of 1vze by Molmil](/molmil-images/mine/1vze) | L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH DUMP AND CB3717 | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | Deposit date: | 1996-09-18 | Release date: | 1997-03-12 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis. Protein Eng., 11, 1998
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8JKT
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2VCZ
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![BU of 2vcz by Molmil](/molmil-images/mine/2vcz) | Complex structure of prostaglandin D2 synthase at 1.95A. | Descriptor: | 3-(4-nitrophenyl)-1H-pyrazole, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE | Authors: | Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. | Deposit date: | 2007-09-28 | Release date: | 2008-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
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3M8B
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![BU of 3m8b by Molmil](/molmil-images/mine/3m8b) | Crystal structure of spin-labeled BtuB V10R1 in the apo state | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ... | Authors: | Freed, D.M, Horanyi, P.S, Wiener, M.C, Cafiso, D.S. | Deposit date: | 2010-03-17 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Conformational exchange in a membrane transport protein is altered in protein crystals. Biophys.J., 99, 2010
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1VZD
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![BU of 1vzd by Molmil](/molmil-images/mine/1vzd) | L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH FDUMP AND CB3717 | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | Deposit date: | 1996-09-18 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis. Protein Eng., 11, 1998
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2Y4Z
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![BU of 2y4z by Molmil](/molmil-images/mine/2y4z) | Structure of the amino-terminal capsid restriction escape mutation N- MLV L10W | Descriptor: | CAPSID PROTEIN P30, GLYCEROL | Authors: | Goldstone, D.C, Holden-Dye, K, Ohkura, S, Stoye, J.P, Taylor, I.A. | Deposit date: | 2011-01-11 | Release date: | 2011-11-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Novel Escape Mutants Suggest an Extensive Trim5Alpha Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein. Plos Pathog., 7, 2011
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1VZC
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1VZA
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![BU of 1vza by Molmil](/molmil-images/mine/1vza) | |
2VD0
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![BU of 2vd0 by Molmil](/molmil-images/mine/2vd0) | Complex structure of prostaglandin D2 synthase at 2.2A. | Descriptor: | 2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, ... | Authors: | Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K. | Deposit date: | 2007-09-28 | Release date: | 2008-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design. J.Med.Chem., 51, 2008
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6HBY
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![BU of 6hby by Molmil](/molmil-images/mine/6hby) | HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope | Descriptor: | 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J. | Deposit date: | 2018-08-13 | Release date: | 2019-08-14 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. J.Biol.Chem., 294, 2019
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3MC4
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![BU of 3mc4 by Molmil](/molmil-images/mine/3mc4) | |
2V9F
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1VVC
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2XM1
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![BU of 2xm1 by Molmil](/molmil-images/mine/2xm1) | BtGH84 in complex with N-acetyl gluconolactam | Descriptor: | GLYCEROL, N-ACETYL GLUCONOLACTAM, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2010-07-22 | Release date: | 2011-08-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of a Bacterial O-Glcnacase Homologue by Lactone and Lactam Derivatives: Structural, Kinetic and Thermodynamic Analyses. Amino Acids, 40, 2011
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6HIN
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![BU of 6hin by Molmil](/molmil-images/mine/6hin) | Mouse serotonin 5-HT3 receptor, serotonin-bound, F conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | Authors: | Polovinkin, L, Neumann, E, Schoehn, G, Nury, H. | Deposit date: | 2018-08-30 | Release date: | 2018-11-07 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Conformational transitions of the serotonin 5-HT3receptor. Nature, 563, 2018
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2XPY
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![BU of 2xpy by Molmil](/molmil-images/mine/2xpy) | Structure of Native Leukotriene A4 Hydrolase from Saccharomyces cerevisiae | Descriptor: | GLUTATHIONE, GLYCEROL, LEUKOTRIENE A-4 HYDROLASE, ... | Authors: | Helgstrand, C, Hasan, M, Usyal, H, Haeggstrom, J.Z, Thunnissen, M.M.G.M. | Deposit date: | 2010-08-31 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | A Leukotriene A(4) Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit Upon Inhibitor Binding. J.Mol.Biol., 406, 2011
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6HJI
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![BU of 6hji by Molmil](/molmil-images/mine/6hji) | Xray structure of GLIC in complex with crotonate | Descriptor: | BUTENOIC ACID, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Fourati, Z, Delarue, M. | Deposit date: | 2018-09-03 | Release date: | 2019-09-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel. Acta Crystallogr D Struct Biol, 76, 2020
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3MFP
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![BU of 3mfp by Molmil](/molmil-images/mine/3mfp) | Atomic model of F-actin based on a 6.6 angstrom resolution cryoEM map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Fujii, T, Iwane, A.H, Yanagida, T, Namba, K. | Deposit date: | 2010-04-03 | Release date: | 2010-09-29 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Direct visualization of secondary structures of F-actin by electron cryomicroscopy Nature, 467, 2010
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8J8M
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![BU of 8j8m by Molmil](/molmil-images/mine/8j8m) | Overall structure of the LAT1-4F2hc bound with tryptophan | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, ... | Authors: | Yan, R.H, Li, Y.N, Shi, T.H. | Deposit date: | 2023-05-02 | Release date: | 2024-07-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Overall structure of the LAT1-4F2hc bound with tryptophan To Be Published
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2XV2
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![BU of 2xv2 by Molmil](/molmil-images/mine/2xv2) | Pseudomonas aeruginosa Azurin with mutated metal-binding loop sequence (CAAHAAM), chemically reduced, pH4.2 | Descriptor: | AZURIN, COPPER (I) ION | Authors: | Li, C, Sato, K, Monari, S, Salard, I, Sola, M, Banfield, M.J, Dennison, C. | Deposit date: | 2010-10-22 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Metal-Binding Loop Length is a Determinant of the Pka of a Histidine Ligand at a Type 1 Copper Site Inorg.Chem., 50, 2011
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8J8L
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![BU of 8j8l by Molmil](/molmil-images/mine/8j8l) | Overall structure of the LAT1-4F2hc bound with L-dopa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-DIHYDROXYPHENYLALANINE, 4F2 cell-surface antigen heavy chain, ... | Authors: | Yan, R.H, Li, Y.N, Shi, T.H. | Deposit date: | 2023-05-02 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Overall structure of the LAT1-4F2hc bound with L-dopa To Be Published
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