8IJ3
| Cryo-EM structure of human HCAR2-Gi complex without ligand (apo state) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Pan, X, Fang, Y. | Deposit date: | 2023-02-24 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2. Cell Discov, 9, 2023
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8IJB
| Cryo-EM structure of human HCAR2-Gi complex with acipimox | Descriptor: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Pan, X, Fang, Y. | Deposit date: | 2023-02-27 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2. Cell Discov, 9, 2023
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7XQ4
| Drimenyl diphosphate synthase from Streptomyces showdoensis (apo) | Descriptor: | SQHop_cyclase_C domain-containing protein | Authors: | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | Deposit date: | 2022-05-06 | Release date: | 2023-03-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XRA
| Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+ | Descriptor: | FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | Authors: | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | Deposit date: | 2022-05-09 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XQZ
| Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+ | Descriptor: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | Authors: | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | Deposit date: | 2022-05-09 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XRU
| Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+ | Descriptor: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | Authors: | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | Deposit date: | 2022-05-11 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XCA
| Crystal structure of the porcine astrovirus capsid spike domain | Descriptor: | CHLORIDE ION, Capsid protein spike domain, MAGNESIUM ION | Authors: | Pan, L.X, Zhang, W.C, Yang, D.F, Yang, L.Y, Liu, H. | Deposit date: | 2022-03-23 | Release date: | 2023-03-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure analysis of porcine astrovirus capsid spike and spike/neutralizing antibody complexes. To Be Published
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7XR7
| Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+ | Descriptor: | FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | Authors: | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | Deposit date: | 2022-05-09 | Release date: | 2023-03-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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4N9L
| crystal structure of beta-lactamse PenP_E166S in complex with meropenem | Descriptor: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-21 | Release date: | 2014-09-10 | Last modified: | 2022-02-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4N9K
| crystal structure of beta-lactamse PenP_E166S in complex with cephaloridine | Descriptor: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-21 | Release date: | 2014-09-10 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4N92
| Crystal structure of beta-lactamse PenP_E166S | Descriptor: | Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-19 | Release date: | 2014-09-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4QTZ
| Crystal Structure of Cinnamyl-Alcohol Dehydrogenase 2 | Descriptor: | Dihydroflavonol-4-reductase | Authors: | Pan, H, Wang, X. | Deposit date: | 2014-07-10 | Release date: | 2014-10-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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4QUK
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4RAG
| CRYSTAL STRUCTURE of PPC2A-D38K | Descriptor: | MANGANESE (II) ION, Protein phosphatase 1A | Authors: | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | Deposit date: | 2014-09-10 | Release date: | 2015-08-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
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4RAF
| Crystal structure of PP2Ca-D38A | Descriptor: | MANGANESE (II) ION, Protein phosphatase 1A | Authors: | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | Deposit date: | 2014-09-10 | Release date: | 2015-08-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
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4RA2
| PP2Ca | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A | Authors: | Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. | Deposit date: | 2014-09-09 | Release date: | 2015-05-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The catalytic role of the M2 metal ion in PP2Ca SCI REP, 2015
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7WH1
| structure of C elegans BCMO-2 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7WH0
| structure of C elegans BCMO-1 | Descriptor: | Beta-Carotene 15,15'-MonoOxygenase, FE (III) ION, GLYCEROL, ... | Authors: | Pan, W, Liu, L. | Deposit date: | 2021-12-29 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans . Front Mol Biosci, 9, 2022
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7DZ8
| State transition supercomplex PSI-LHCI-LHCII from the LhcbM1 lacking mutant of Chlamydomonas reinhardtii | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-23 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7E0H
| LHCII-1 in the state transition supercomplex PSI-LHCI-LHCII from the LhcbM1 lacking mutant of Chlamydomonas reinhardtii | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-28 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7E0J
| LHCII-1 in the state transition supercomplex PSI-LHCI-LHCII from the double phosphatase mutant pph1;pbcp of Chlamydomonas reinhardti. | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-28 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7DZ7
| State transition supercomplex PSI-LHCI-LHCII from double phosphatase mutant pph1;pbcp of green alga Chlamydomonas reinhardtii | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-23 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7E0I
| LHCII-2 in the state transition supercomplex PSI-LHCI-LHCII from the LhcbM1 lacking mutant of Chlamydomonas reinhardti | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-28 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7E0K
| LHCII-2 in the state transition supercomplex PSI-LHCI-LHCII from the double phosphatase mutant pph1;pbcp of Chlamydomonas reinhardti. | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, A.J, Liu, Z.F, Li, M. | Deposit date: | 2021-01-28 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural basis of LhcbM5-mediated state transitions in green algae. Nat.Plants, 7, 2021
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7E7M
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