1DRZ
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![BU of 1drz by Molmil](/molmil-images/mine/1drz) | U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX | Descriptor: | MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ... | Authors: | Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A. | Deposit date: | 1998-09-01 | Release date: | 1999-02-16 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a hepatitis delta virus ribozyme. Nature, 395, 1998
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1ZN0
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![BU of 1zn0 by Molmil](/molmil-images/mine/1zn0) | Coordinates of RRF and EF-G fitted into Cryo-EM map of the 50S subunit bound with both EF-G (GDPNP) and RRF | Descriptor: | 16S RIBOSOMAL RNA, ELONGATION FACTOR G, Ribosome recycling factor | Authors: | Gao, N, Zavialov, A.V, Li, W, Sengupta, J, Valle, M, Gursky, R.P, Ehrenberg, M, Frank, J. | Deposit date: | 2005-05-11 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (15.5 Å) | Cite: | Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol.Cell, 18, 2005
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8TCA
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![BU of 8tca by Molmil](/molmil-images/mine/8tca) | Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting N6-methyladenosine (m6A), an RNA modification, no ligand | Descriptor: | 1,2-ETHANEDIOL, m6A binding IgG Fab, heavy chain, ... | Authors: | Angelo, M.C, Aoki, S.T. | Deposit date: | 2023-06-30 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting N6-methyladenosine (m6A), an RNA modification To Be Published
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1BY0
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![BU of 1by0 by Molmil](/molmil-images/mine/1by0) | |
6Y3P
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![BU of 6y3p by Molmil](/molmil-images/mine/6y3p) | |
4E8Q
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![BU of 4e8q by Molmil](/molmil-images/mine/4e8q) | |
4E8N
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![BU of 4e8n by Molmil](/molmil-images/mine/4e8n) | |
4E8V
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![BU of 4e8v by Molmil](/molmil-images/mine/4e8v) | |
5SWD
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![BU of 5swd by Molmil](/molmil-images/mine/5swd) | Structure of the adenine riboswitch aptamer domain in an intermediate-bound state | Descriptor: | ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ... | Authors: | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | Deposit date: | 2016-08-08 | Release date: | 2016-11-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
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5SWE
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![BU of 5swe by Molmil](/molmil-images/mine/5swe) | Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography | Descriptor: | ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain | Authors: | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | Deposit date: | 2016-08-08 | Release date: | 2016-11-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
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5DH7
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![BU of 5dh7 by Molmil](/molmil-images/mine/5dh7) | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-G12A mutant in Mn2+ | Descriptor: | 5'-R(*GP*GP*GP*CP*GP*UP*DC*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION, RNA (48-MER) | Authors: | Mir, A, Chen, J, Neau, D, Golden, B.L. | Deposit date: | 2015-08-29 | Release date: | 2015-10-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.064 Å) | Cite: | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54, 2015
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4E8R
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![BU of 4e8r by Molmil](/molmil-images/mine/4e8r) | |
6M2B
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![BU of 6m2b by Molmil](/molmil-images/mine/6m2b) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with S416 | Descriptor: | 2-[(E)-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methyl-hydrazinylidene]methyl]benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Li, H. | Deposit date: | 2020-02-27 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein Cell, 11, 2020
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4E8P
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![BU of 4e8p by Molmil](/molmil-images/mine/4e8p) | |
4E8K
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![BU of 4e8k by Molmil](/molmil-images/mine/4e8k) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Ca2+ and a non-hydrolyzed oligonucleotide substrate | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-R(*CP*G*AP*UP*UP*UP*AP*UP*UP*A)-3', CALCIUM ION, ... | Authors: | Marcia, M, Pyle, A.M. | Deposit date: | 2012-03-20 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Visualizing Group II Intron Catalysis through the Stages of Splicing. Cell(Cambridge,Mass.), 151, 2012
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5DH8
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![BU of 5dh8 by Molmil](/molmil-images/mine/5dh8) | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction- G12A mutant in Zn2+ | Descriptor: | 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', RNA (48-MER), ZINC ION | Authors: | Mir, A, Chen, J, Neau, D, Golden, B.L. | Deposit date: | 2015-08-29 | Release date: | 2015-10-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.297 Å) | Cite: | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54, 2015
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4E8M
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![BU of 4e8m by Molmil](/molmil-images/mine/4e8m) | |
4FJO
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![BU of 4fjo by Molmil](/molmil-images/mine/4fjo) | Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex | Descriptor: | DNA polymerase kappa, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ... | Authors: | Wojtaszek, J, Lee, C.-J, Zhou, P. | Deposit date: | 2012-06-11 | Release date: | 2012-08-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.718 Å) | Cite: | Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol zeta and Pol kappa J.Biol.Chem., 287, 2012
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1B8I
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![BU of 1b8i by Molmil](/molmil-images/mine/1b8i) | STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX | Descriptor: | DNA (5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3'), PROTEIN (HOMEOBOX PROTEIN EXTRADENTICLE), ... | Authors: | Passner, J.M, Ryoo, H.-D, Shen, L, Mann, R.S, Aggarwal, A.K. | Deposit date: | 1999-02-01 | Release date: | 1999-04-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature, 397, 1999
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4E8T
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![BU of 4e8t by Molmil](/molmil-images/mine/4e8t) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Ca2+ and an oligonucleotide fragment substrate (low energy dataset) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-R(*AP*UP*UP*UP*AP*UP*UP*A)-3', CALCIUM ION, ... | Authors: | Marcia, M, Pyle, A.M. | Deposit date: | 2012-03-20 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Visualizing Group II Intron Catalysis through the Stages of Splicing. Cell(Cambridge,Mass.), 151, 2012
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5DI4
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![BU of 5di4 by Molmil](/molmil-images/mine/5di4) | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-WT ribozyme in Mn2+ at low pH | Descriptor: | 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION, RNA (48-MER) | Authors: | Mir, A, Chen, J, Neau, D, Golden, B.L. | Deposit date: | 2015-08-31 | Release date: | 2015-10-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.948 Å) | Cite: | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54, 2015
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6N34
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![BU of 6n34 by Molmil](/molmil-images/mine/6n34) | Crystal structure of the BTB domain of Human NS1-BP | Descriptor: | Influenza virus NS1A-binding protein | Authors: | Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M. | Deposit date: | 2018-11-14 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5T5A
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![BU of 5t5a by Molmil](/molmil-images/mine/5t5a) | |
4FAX
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![BU of 4fax by Molmil](/molmil-images/mine/4fax) | |
7YCI
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![BU of 7yci by Molmil](/molmil-images/mine/7yci) | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | Deposit date: | 2022-07-01 | Release date: | 2023-07-05 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM. Nucleic Acids Res., 51, 2023
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