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1RSV
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BU of 1rsv by Molmil
azide complex of the diferrous E238A mutant R2 subunit of ribonucleotide reductase
Descriptor: AZIDE ION, FE (III) ION, MERCURY (II) ION, ...
Authors:Assarsson, M, Andersson, M.E, Hogbom, M, Persson, B.O, Sahlin, M, Barra, A.L, Sjoberg, B.M, Nordlund, P, Graslund, A.
Deposit date:2003-12-10
Release date:2003-12-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli.
J.Biol.Chem., 276, 2001
6EBO
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BU of 6ebo by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Unactivated Form
Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
Authors:Palowitch, G.M, Alapati, R.B, Boal, A.K.
Deposit date:2018-08-06
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBZ
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BU of 6ebz by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form with Thiocyanate Bound
Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
Authors:Palowitch, G.M, Boal, A.K.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBP
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BU of 6ebp by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form
Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
Authors:Palowitch, G.M, Boal, A.K.
Deposit date:2018-08-06
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6F6C
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BU of 6f6c by Molmil
R2-like ligand-binding oxidase V72A mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.766 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F6K
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BU of 6f6k by Molmil
R2-like ligand-binding oxidase V72L mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, LAURIC ACID, MANGANESE (II) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.982 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F6H
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BU of 6f6h by Molmil
R2-like ligand-binding oxidase V72L mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F6M
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BU of 6f6m by Molmil
R2-like ligand-binding oxidase Y162F mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.393 Å)
Cite:Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 24, 2019
6F6L
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BU of 6f6l by Molmil
R2-like ligand-binding oxidase Y162F mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 24, 2019
6F6G
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BU of 6f6g by Molmil
R2-like ligand-binding oxidase V72I mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F6B
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BU of 6f6b by Molmil
R2-like ligand-binding oxidase A171F mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 24, 2019
6F6E
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BU of 6f6e by Molmil
R2-like ligand-binding oxidase V72A mutant with anaerobically reconstituted Mn/Fe cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.627 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F6F
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BU of 6f6f by Molmil
R2-like ligand-binding oxidase V72I mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-07-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.788 Å)
Cite:Ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 23, 2018
6F65
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BU of 6f65 by Molmil
R2-like ligand-binding oxidase A171F mutant with aerobically reconstituted Mn/Fe cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-12-05
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.948 Å)
Cite:Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase.
J. Biol. Inorg. Chem., 24, 2019
6GP2
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BU of 6gp2 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, DOPA-active form
Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
Authors:Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
6GP3
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BU of 6gp3 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, inactive form
Descriptor: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
Authors:Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
6W4X
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BU of 6w4x by Molmil
Holocomplex of E. coli class Ia ribonucleotide reductase with GDP and TTP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ...
Authors:Kang, G, Taguchi, A, Stubbe, J, Drennan, C.
Deposit date:2020-03-11
Release date:2020-04-08
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex.
Science, 368, 2020
7Z3D
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BU of 7z3d by Molmil
XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with oxidized NrdI from Bacillus cereus
Descriptor: FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein NrdI, ...
Authors:John, J, Lebrette, H, Aurelius, O, Hogbom, M.
Deposit date:2022-03-02
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
7Z3E
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BU of 7z3e by Molmil
XFEL structure of Class Ib ribonucleotide reductase dimanganese(II) NrdF in complex with hydroquinone NrdI from Bacillus cereus
Descriptor: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, MANGANESE (II) ION, Protein NrdI, ...
Authors:John, J, Lebrette, H, Aurelius, O, Hogbom, M.
Deposit date:2022-03-02
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redox-controlled reorganization and flavin strain within the ribonucleotide reductase R2b-NrdI complex monitored by serial femtosecond crystallography.
Elife, 11, 2022
5OLK
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BU of 5olk by Molmil
Crystal structure of the ATP-cone-containing NrdB from Leeuwenhoekiella blandensis
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
Authors:Hasan, M, Grinberg, A.R, Sjoberg, B.M, Logan, D.T.
Deposit date:2017-07-28
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit.
Elife, 7, 2018
2BQ1
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BU of 2bq1 by Molmil
Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, FE (III) ION, MAGNESIUM ION, ...
Authors:Uppsten, M, Farnegardh, M, Domkin, V, Uhlin, U.
Deposit date:2005-04-26
Release date:2006-05-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into its Mechanism of Action
J.Mol.Biol., 359, 2006
3UUS
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BU of 3uus by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
Authors:Zimanyi, C.M, Drennan, C.L.
Deposit date:2011-11-28
Release date:2011-12-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (5.65 Å)
Cite:Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3N3A
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BU of 3n3a by Molmil
Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI
Descriptor: FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ...
Authors:Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C.
Deposit date:2010-05-19
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for activation of class Ib ribonucleotide reductase.
Science, 329, 2010
3N39
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BU of 3n39 by Molmil
Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with NrdI
Descriptor: FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, Protein nrdI, ...
Authors:Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C.
Deposit date:2010-05-19
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for activation of class Ib ribonucleotide reductase.
Science, 329, 2010
3N3B
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BU of 3n3b by Molmil
Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI with a Trapped Peroxide
Descriptor: FLAVIN MONONUCLEOTIDE, HYDROGEN PEROXIDE, MANGANESE (II) ION, ...
Authors:Boal, A.K, Cotruvo Jr, J.A, Stubbe, J, Rosenzweig, A.C.
Deposit date:2010-05-19
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis for activation of class Ib ribonucleotide reductase.
Science, 329, 2010

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