7UIX
| ClpAP complex bound to ClpS N-terminal extension, class I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIV
| ClpAP complex bound to ClpS N-terminal extension, class IIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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8CVT
| Human 19S-20S proteasome, state SD2 | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | Authors: | Zhao, J. | Deposit date: | 2022-05-18 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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8A8U
| Mycobacterium tuberculosis ClpC1 hexamer structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8V
| Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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8A8W
| Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
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7UIY
| ClpAP complex bound to ClpS N-terminal extension, class IIIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-10-26 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7WTL
| Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-D | Descriptor: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | Authors: | Cheng, J, La Venuta, G, Lau, B, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2022-02-05 | Release date: | 2022-10-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Nucleic Acids Res., 50, 2022
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7W42
| Crystal structure of Bacillus subtilis YjoB | Descriptor: | Uncharacterized ATPase YjoB | Authors: | Dahal, P, Kwon, E, Kim, D.Y. | Deposit date: | 2021-11-26 | Release date: | 2022-10-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.619 Å) | Cite: | Crystal structure and biochemical analysis suggest that YjoB ATPase is a putative substrate-specific molecular chaperone. Proc.Natl.Acad.Sci.USA, 119, 2022
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7W46
| Crystal structure of Bacillus subtilis YjoB with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Uncharacterized ATPase YjoB | Authors: | Dahal, P, Kwon, E, Kim, D.Y. | Deposit date: | 2021-11-26 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and biochemical analysis suggest that YjoB ATPase is a putative substrate-specific molecular chaperone. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TJK
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | Authors: | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | Deposit date: | 2022-01-16 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJJ
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | Authors: | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | Deposit date: | 2022-01-16 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJI
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | Authors: | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | Deposit date: | 2022-01-16 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7TJH
| S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ... | Authors: | Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F. | Deposit date: | 2022-01-16 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6. Nat Commun, 13, 2022
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7Z34
| Structure of pre-60S particle bound to DRG1(AFG2). | Descriptor: | 35S pre-ribosomal RNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Prattes, M, Grishkovskaya, I, Bergler, H, Haselbach, D. | Deposit date: | 2022-03-01 | Release date: | 2022-09-21 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Nat.Struct.Mol.Biol., 29, 2022
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7Z11
| Structure of substrate bound DRG1 (AFG2) | Descriptor: | ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, peptide substrate | Authors: | Prattes, M, Grishkovskaya, I, Bergler, H, Haselbach, D. | Deposit date: | 2022-02-24 | Release date: | 2022-09-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Nat.Struct.Mol.Biol., 29, 2022
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8AMZ
| Spinach 19S proteasome | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ... | Authors: | Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. | Deposit date: | 2022-08-04 | Release date: | 2022-08-24 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the plant 26S proteasome Plant Communications, 3, 2022
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8DR0
| Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DQZ
| Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DQX
| Open state of RFC:PCNA bound to a 3' ss/dsDNA junction | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR6
| Closed state of RFC:PCNA bound to a nicked dsDNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-24 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.39 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR4
| Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD | Descriptor: | DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR7
| Open state of RFC:PCNA bound to a nicked dsDNA | Descriptor: | DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR3
| Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR5
| Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD | Descriptor: | DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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