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1AXI
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STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE
Descriptor: GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION
Authors:Atwell, S, Ultsch, M, De Vos, A.M, Wells, J.A.
Deposit date:1997-10-15
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural plasticity in a remodeled protein-protein interface.
Science, 278, 1997
1AXJ
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FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F), NMR, 20 STRUCTURES
Descriptor: FLAVIN MONONUCLEOTIDE, FMN-BINDING PROTEIN
Authors:Liepinsh, E, Otting, G.
Deposit date:1997-10-16
Release date:1998-01-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Pathway of chymotrypsin evolution suggested by the structure of the FMN-binding protein from Desulfovibrio vulgaris (Miyazaki F)
Nat.Struct.Biol., 4, 1997
1AXK
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ENGINEERED BACILLUS BIFUNCTIONAL ENZYME GLUXYN-1
Descriptor: CALCIUM ION, GLUXYN-1
Authors:Ay, J, Heinemann, U.
Deposit date:1997-10-16
Release date:1999-05-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of the Bacillus hybrid enzyme GluXyn-1: native-like jellyroll fold preserved after insertion of autonomous globular domain.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AXL
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SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG)
Authors:Feng, B, Gorin, A.A, Kolbanovskiy, A, Hingerty, B.E, Geacintov, N.E, Broyde, S, Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Biochemistry, 36, 1997
1AXM
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HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR
Authors:DiGabriele, A.D, Lax, I, Chen, D.I, Svahn, C.M, Jaye, M, Schlessinger, J, Hendrickson, W.A.
Deposit date:1997-10-16
Release date:1998-04-22
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
Nature, 393, 1998
1AXN
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THE HIGH RESOLUTION STRUCTURE OF ANNEXIN III SHOWS DIFFERENCES WITH ANNEXIN V
Descriptor: ANNEXIN III, CALCIUM ION
Authors:Favier-Perron, B, Lewit-Bentley, A, Russo-Marie, F.
Deposit date:1995-08-21
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:The high-resolution crystal structure of human annexin III shows subtle differences with annexin V.
Biochemistry, 35, 1996
1AXO
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STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(AAC-[BP]G-CTACCATCC)D(GGATGGTAGC)
Authors:Feng, B, Gorin, A.A, Hingerty, B.E, Geacintov, N.E, Broyde, S, Patel, D.J.
Deposit date:1997-10-16
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Biochemistry, 36, 1997
1AXP
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DNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 6 STRUCTURES
Descriptor: DNA (D(GAAGAGAAGC)(DOT)D(GCTTCTCTTC))
Authors:Gyi, J.I, Lane, A.N, Conn, G.L, Brown, T.
Deposit date:1997-10-17
Release date:1998-04-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry, 37, 1998
1AXQ
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FERRICYANIDE OXIDIZED FDI
Descriptor: FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER
Authors:Stout, C.D.
Deposit date:1997-10-17
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of ferricyanide-oxidized [Fe-S] clusters in Azotobacter vinelandii ferredoxin I.
J.Biol.Inorg.Chem., 3, 1998
1AXR
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COOPERATIVITY BETWEEN HYDROGEN-BONDING AND CHARGE-DIPOLE INTERACTIONS IN THE INHIBITION OF BETA-GLYCOSIDASES BY AZOLOPYRIDINES: EVIDENCE FROM A STUDY WITH GLYCOGEN PHOSPHORYLASE B
Descriptor: 4,5,6-TRIHYDROXY-7-HYDROXYMETHYL-4,5,6,7-TETRAHYDRO-1H-[1,2,3]TRIAZOLO[1,5-A]PYRIDIN-8-YLIUM, GLYCOGEN PHOSPHORYLASE, PHOSPHATE ION, ...
Authors:Oikonomakos, N.G, Heightman, T.D.
Deposit date:1997-10-20
Release date:1998-01-28
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cooperative interactions of the catalytic nucleophile and the catalytic acid in the inhibition of beta-glycosidases. Calculations and their validation by comparative kinetic and structural studies of the inhibition of glycogen phosphorylase b.
HELV.CHIM.ACTA, 81, 1998
1AXS
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MATURE OXY-COPE CATALYTIC ANTIBODY WITH HAPTEN
Descriptor: (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, OXY-COPE CATALYTIC ANTIBODY
Authors:Mundorff, E.C, Ulrich, H.D, Stevens, R.C.
Deposit date:1997-10-20
Release date:1998-02-04
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
Nature, 389, 1997
1AXT
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BU of 1axt by Molmil
IMMUNE VERSUS NATURAL SELECTION: ANTIBODY ALDOLASES WITH THE RATES OF NATURAL ENZYMES
Descriptor: IMMUNOGLOBULIN IGG2A
Authors:Heine, A, Wilson, I.A.
Deposit date:1997-10-20
Release date:1998-10-28
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Immune versus natural selection: antibody aldolases with enzymic rates but broader scope.
Science, 278, 1997
1AXU
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BU of 1axu by Molmil
SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES
Descriptor: DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG), N-1-AMINOPYRENE
Authors:Gu, Z, Gorin, A.A, Krishnasami, R, Hingerty, B.E, Basu, A.K, Broyde, S, Patel, D.J.
Deposit date:1997-10-21
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex.
Biochemistry, 38, 1999
1AXV
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SOLUTION NMR STRUCTURE OF THE [BP]DA ADDUCT OPPOSITE DT IN A DNA DUPLEX, 6 STRUCTURES
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(CTCTC-[BP]A-CTTCC)D(GGAAGTGAGAG)
Authors:Mao, B, Gu, Z, Gorin, A.A, Chen, J, Hingerty, B.E, Amid, S, Broyde, S, Geacintov, N.E, Patel, D.J.
Deposit date:1997-10-21
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
Biochemistry, 38, 1999
1AXW
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E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, METHOTREXATE, THYMIDYLATE SYNTHASE
Authors:Stout, T.J, Sage, C.R, Stroud, R.M.
Deposit date:1997-10-23
Release date:1998-10-28
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Thymidylate Synthase Inhibitors Using Flexible Docking and an Empirically Tuned Scoring Function
To be Published
1AXX
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THE SOLUTION STRUCTURE OF OXIDIZED RAT MICROSOMAL CYTOCHROME B5, NMR, 19 STRUCTURES
Descriptor: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Arnesano, F, Banci, L, Bertini, I, Felli, I.C.
Deposit date:1997-10-22
Release date:1998-03-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of oxidized rat microsomal cytochrome b5.
Biochemistry, 37, 1998
1AXY
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ERYTHRINA CORALLODENDRON LECTIN
Descriptor: CALCIUM ION, LECTIN, MANGANESE (II) ION, ...
Authors:Shaanan, B, Elgavish, S.
Deposit date:1997-10-24
Release date:1998-05-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Erythrina corallodendron lectin and of its complexes with mono- and disaccharides.
J.Mol.Biol., 277, 1998
1AXZ
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ERYTHRINA CORALLODENDRON LECTIN IN COMPLEX WITH D-GALACTOSE
Descriptor: CALCIUM ION, LECTIN, MANGANESE (II) ION, ...
Authors:Shaanan, B, Elgavish, S.
Deposit date:1997-10-24
Release date:1998-05-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Erythrina corallodendron lectin and of its complexes with mono- and disaccharides.
J.Mol.Biol., 277, 1998
1AY0
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BU of 1ay0 by Molmil
IDENTIFICATION OF CATALYTICALLY IMPORTANT RESIDUES IN YEAST TRANSKETOLASE
Descriptor: CALCIUM ION, THIAMINE DIPHOSPHATE, TRANSKETOLASE
Authors:Wikner, C, Nilsson, U, Meshalkina, L, Udekwu, C, Lindqvist, Y, Schneider, G.
Deposit date:1997-11-13
Release date:1998-05-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of catalytically important residues in yeast transketolase.
Biochemistry, 36, 1997
1AY1
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ANTI TAQ FAB TP7
Descriptor: TP7 FAB
Authors:Murali, R, Helmer-Citterich, M, Sharkey, D.J, Scalice, E.R, Daiss, J.L, Sullivan, M.A, Murthy, H.M.K.
Deposit date:1997-11-13
Release date:1998-05-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition.
Protein Eng., 11, 1998
1AY2
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STRUCTURE OF THE FIBER-FORMING PROTEIN PILIN AT 2.6 ANGSTROMS RESOLUTION
Descriptor: HEPTANE-1,2,3-TRIOL, PLATINUM (II) ION, TYPE 4 PILIN, ...
Authors:Forest, K.T, Parge, H.E, Tainer, J.A.
Deposit date:1997-11-13
Release date:1998-04-29
Last modified:2023-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the fibre-forming protein pilin at 2.6 A resolution.
Nature, 378, 1995
1AY3
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Nodularin from Nodularia spumigena
Descriptor: PEPTIDIC TOXIN NODULARIN
Authors:Annila, A.J.
Deposit date:1997-11-14
Release date:1999-08-16
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Solution structure of nodularin. An inhibitor of serine/threonine-specific protein phosphatases.
J.Biol.Chem., 271, 1996
1AY4
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AROMATIC AMINO ACID AMINOTRANSFERASE WITHOUT SUBSTRATE
Descriptor: AROMATIC AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Okamoto, A, Hirotsu, K, Kagamiyama, H.
Deposit date:1997-11-14
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
J.Mol.Biol., 280, 1998
1AY5
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AROMATIC AMINO ACID AMINOTRANSFERASE COMPLEX WITH MALEATE
Descriptor: AROMATIC AMINO ACID AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Okamoto, A, Hirotsu, K, Kagamiyama, H.
Deposit date:1997-11-14
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: a substrate recognition site constructed by rearrangement of hydrogen bond network.
J.Mol.Biol., 280, 1998
1AY6
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THROMBIN INHIBITOR FROM THEONALLA, CYCLOTHEANAMIDE-BASED MACROCYCLIC TRIPEPTIDE MOTIF
Descriptor: HIRUGEN, THROMBIN HEAVY CHAIN, THROMBIN LIGHT CHAIN, ...
Authors:Ganesh, V, Maryanoff, B.E, Tulinsky, A.
Deposit date:1997-11-14
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif
Bioorg.Med.Chem.Lett., 6, 1996

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