6S8R
| D. melanogaster RNA helicase Me31B in complex with GIGYF | Descriptor: | ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148 | Authors: | Peter, D, Valkov, E. | Deposit date: | 2019-07-10 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression. Genes Dev., 33, 2019
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6UTY
| E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UTX
| E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.05 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UUB
| E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.955 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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3SSF
| Crystal structure of RNA:DNA dodecamer corresponding to HIV-1 polypurine tract, at 1.6 A resolution. | Descriptor: | 5'-D(*CP*CP*TP*TP*TP*TP*CP*TP*TP*TP*TP*A)-3', 5'-R(*UP*AP*AP*AP*AP*GP*AP*AP*AP*AP*GP*G)-3', MAGNESIUM ION | Authors: | Drozdzal, P, Michalska, K, Kierzek, R, Lomozik, L, Jaskolski, M. | Deposit date: | 2011-07-08 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of an RNA/DNA dodecamer corresponding to the HIV-1 polypurine tract at 1.6 Angstrom resolution Acta Crystallogr.,Sect.D, 68, 2012
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3CF5
| Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans | Descriptor: | 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, 50S RIBOSOMAL PROTEIN L14, ... | Authors: | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | Deposit date: | 2008-03-02 | Release date: | 2008-06-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin. Mol.Cell, 30, 2008
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2DRA
| Complex structure of CCA-adding enzyme with tRNAminiDCC and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ... | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
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2DR7
| Complex structure of CCA-adding enzyme with tRNAminiDC | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (33-MER) | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
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2DRB
| Complex structure of CCA-adding enzyme with tRNAminiCCA | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (35-MER) | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
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2RSM
| Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65 (ICT2) | Descriptor: | Probable peptide chain release factor C12orf65 homolog, mitochondrial | Authors: | Enomoto, M, Tochio, N, Tomizawa, T, Koshiba, S, Guntert, P, Kigawa, T, Yokoyama, S, Nameki, N. | Deposit date: | 2012-03-28 | Release date: | 2012-08-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65. Proteins, 2012
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7QDZ
| 80S-bound human SKI complex in the closed state | Descriptor: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | Authors: | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | Deposit date: | 2021-12-01 | Release date: | 2022-02-09 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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3NXY
| Preferential Selection of Isomer Binding from Chiral Mixtures: Alernate Binding Modes Observed fro the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase | Descriptor: | 5-[(1E,3R)-2-(2-methoxyphenyl)-3-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cody, V. | Deposit date: | 2010-07-14 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 66, 2010
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6S84
| TsaBDE complex from Thermotoga maritima | Descriptor: | ATPase YjeE, predicted to have essential role in cell wall biosynthesis, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | Missoury, S, Li-de-La-Sierra-Gallay, I, van Tilbeurgh, H. | Deposit date: | 2019-07-08 | Release date: | 2019-07-17 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification. Nucleic Acids Res., 46, 2018
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6UUA
| E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours) | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.002 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6O8W
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6OMF
| CryoEM structure of SigmaS-transcription initiation complex with activator Crl | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. | Deposit date: | 2019-04-18 | Release date: | 2019-08-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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4Z92
| crystal structure of parechovirus-1 virion | Descriptor: | Capsid subunit VP3, RNA (5'-R(*AP*UP*UP*UP*UP*U)-3'), capsid subunit VP0, ... | Authors: | Kalynych, S, Palkova, L, Plevka, P. | Deposit date: | 2015-04-09 | Release date: | 2015-11-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid. J.Virol., 90, 2015
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7Y41
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6XJF
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6VPC
| Structure of the SpCas9 DNA adenine base editor - ABE8e | Descriptor: | CRISPR-associated endonuclease Cas9, Cas9 (SpCas9) single-guide RNA (sgRNA), DNA non-target strand (NTS), ... | Authors: | Knott, G.J, Lapinaite, A, Doudna, J.A. | Deposit date: | 2020-02-03 | Release date: | 2020-07-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | DNA capture by a CRISPR-Cas9-guided adenine base editor. Science, 369, 2020
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2F96
| 2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T) | Descriptor: | MAGNESIUM ION, Ribonuclease T | Authors: | Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-05 | Release date: | 2006-02-14 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover. Structure, 15, 2007
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2R1G
| Coordinates of the thermus thermophilus 30S components neighboring RbfA as obtained by fitting into the CRYO-EM map of A 30S-RBFA complex | Descriptor: | 16S RIBOSOMAL RNA HELIX 1, 16S RIBOSOMAL RNA HELIX 18, 16S RIBOSOMAL RNA HELIX 27, ... | Authors: | Datta, P.P, Wilson, D.N, Kawazoe, M, Swami, N.K, Kaminishi, T, Sharma, M.R, Booth, T.M, Takemoto, C, Fucini, P, Yokoyama, S, Agrawal, R.K. | Deposit date: | 2007-08-22 | Release date: | 2008-03-18 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | Structural aspects of RbfA action during small ribosomal subunit assembly. Mol.Cell, 28, 2007
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8H8E
| Structure of the dimeric Xenopus tropical acid-sensitive outwardly rectifying channel ASOR trimer bound with tRNA (closed state) | Descriptor: | Proton-activated chloride channel, tRNA (75-MER)of Spodoptera frugiperda | Authors: | Chi, P, Wang, X, Li, J, Li, K, Zhang, Y, Geng, J, Wu, J, Deng, D. | Deposit date: | 2022-10-22 | Release date: | 2024-05-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA. Cell Res., 34, 2024
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6KG1
| NifS from Helicobacter pylori, soaked with L-cysteine for 180 sec | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KG0
| NifS from Helicobacter pylori, soaked with L-cysteine for 118 sec | Descriptor: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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