8DUW
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![BU of 8duw by Molmil](/molmil-images/mine/8duw) | HnRNPA2 D290V LCD PM2 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | Deposit date: | 2022-07-27 | Release date: | 2023-08-02 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300, 2023
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2GIL
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![BU of 2gil by Molmil](/molmil-images/mine/2gil) | Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-6A | Authors: | Bergbrede, T, Pylypenko, O, Rak, A, Alexandrov, K. | Deposit date: | 2006-03-29 | Release date: | 2006-06-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution J.STRUCT.BIOL., 152, 2005
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2GDI
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8EC7
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![BU of 8ec7 by Molmil](/molmil-images/mine/8ec7) | HnRNPA2 D290V LCD PM3 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | Deposit date: | 2022-09-01 | Release date: | 2023-09-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300, 2023
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2G2N
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![BU of 2g2n by Molmil](/molmil-images/mine/2g2n) | Crystal Structure of E.coli transthyretin-related protein with bound Zn | Descriptor: | SULFATE ION, Transthyretin-like protein, ZINC ION | Authors: | Lundberg, E, Backstrom, S, Sauer, U.H, Sauer-Eriksson, A.E. | Deposit date: | 2006-02-16 | Release date: | 2006-12-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The transthyretin-related protein: structural investigation of a novel protein family J.Struct.Biol., 155, 2006
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7BKY
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![BU of 7bky by Molmil](/molmil-images/mine/7bky) | Endothiapepsin structure obtained at 298K with fragment BTB09871 bound from a dataset collected with JUNGFRAU detector | Descriptor: | DIMETHYL SULFOXIDE, Endothiapepsin, PENTAETHYLENE GLYCOL, ... | Authors: | Engilberge, S, Huang, C.-Y, Leonarski, F, Wojdyla, J.A, Marsh, M, Olieric, V, Wang, M. | Deposit date: | 2021-01-17 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Endothiapepsin structure obtained at 298K with fragment BTB09871 bound from a dataset collected with JUNGFRAU detector To Be Published
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2MKY
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7R60
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![BU of 7r60 by Molmil](/molmil-images/mine/7r60) | BTK in complex with 18A | Descriptor: | 2-(4-phenoxyphenoxy)-5-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide, Tyrosine-protein kinase BTK | Authors: | Gardberg, A. | Deposit date: | 2021-06-22 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity. Chemmedchem, 16, 2021
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5KNM
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7R61
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![BU of 7r61 by Molmil](/molmil-images/mine/7r61) | BTK in complex with 25A | Descriptor: | 5-{(3S)-1-[(Z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide, DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK | Authors: | Gardberg, A. | Deposit date: | 2021-06-22 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity. Chemmedchem, 16, 2021
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8GBD
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![BU of 8gbd by Molmil](/molmil-images/mine/8gbd) | Homo sapiens Zalpha mutant - P193A | Descriptor: | Double-stranded RNA-specific adenosine deaminase | Authors: | Langeberg, C.J, Vogeli, B, Nichols, P.J, Henen, M, Vicens, Q. | Deposit date: | 2023-02-25 | Release date: | 2023-03-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome. J.Mol.Biol., 435, 2023
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8GBC
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![BU of 8gbc by Molmil](/molmil-images/mine/8gbc) | Homo sapiens Zalpha mutant - N173S | Descriptor: | Double-stranded RNA-specific adenosine deaminase | Authors: | Langeberg, C.J, Nichols, P.J, Henen, M, Vicens, Q, Vogeli, B. | Deposit date: | 2023-02-25 | Release date: | 2023-03-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome. J.Mol.Biol., 435, 2023
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4W4M
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![BU of 4w4m by Molmil](/molmil-images/mine/4w4m) | Crystal structure of PrgK 19-92 | Descriptor: | Lipoprotein PrgK | Authors: | Bergeron, J.R.C, Strynadka, N.C.J. | Deposit date: | 2014-08-15 | Release date: | 2014-10-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure, 23, 2015
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4W50
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![BU of 4w50 by Molmil](/molmil-images/mine/4w50) | Structure of the EphA4 LBD in complex with peptide | Descriptor: | 1,3-BUTANEDIOL, APY peptide, Ephrin type-A receptor 4, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Riedl, S.J. | Deposit date: | 2014-08-16 | Release date: | 2014-10-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor. Acs Chem.Biol., 9, 2014
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2PL3
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![BU of 2pl3 by Molmil](/molmil-images/mine/2pl3) | Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ETHANOL, MAGNESIUM ION, ... | Authors: | Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | Deposit date: | 2007-04-19 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
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2P6N
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![BU of 2p6n by Molmil](/molmil-images/mine/2p6n) | Human DEAD-box RNA helicase DDX41, helicase domain | Descriptor: | ATP-dependent RNA helicase DDX41 | Authors: | Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | Deposit date: | 2007-03-19 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
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1IRV
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1IRW
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2N2J
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2XK0
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![BU of 2xk0 by Molmil](/molmil-images/mine/2xk0) | Solution structure of the Tudor domain from Drosophila Polycomblike (Pcl) | Descriptor: | POLYCOMB PROTEIN PCL | Authors: | Friberg, A, Oddone, A, Klymenko, T, Mueller, J, Sattler, M. | Deposit date: | 2010-07-07 | Release date: | 2010-08-11 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure of an Atypical Tudor Domain in the Drosophila Polycomblike Protein Protein Sci., 19, 2010
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7QTV
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![BU of 7qtv by Molmil](/molmil-images/mine/7qtv) | Beryllium fluoride form of the Na+,K+-ATPase (E2-BeFx) | Descriptor: | 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shahsavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. | Deposit date: | 2022-01-16 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.05 Å) | Cite: | The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. J.Biol.Chem., 298, 2022
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5KGE
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5KGI
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5KGD
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7RAS
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![BU of 7ras by Molmil](/molmil-images/mine/7ras) | Structure of TRPV3 in complex with osthole | Descriptor: | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Transient receptor potential cation channel subfamily V member 3 | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2021-07-02 | Release date: | 2021-09-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole. Embo Rep., 22, 2021
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