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4JNZ
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BU of 4jnz by Molmil
Crystal structure of PutA86-630 mutant D370N complexed with L-Tetrahydro-2-furoic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J.
Deposit date:2013-03-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Involvement of the beta 3-alpha 3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A.
Biochemistry, 52, 2013
2IJA
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BU of 2ija by Molmil
Human N-acetyltransferase 1 F125S mutant
Descriptor: ACETAMIDE, Arylamine N-acetyltransferase 1, SODIUM ION, ...
Authors:Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Grant, D.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
Deposit date:2006-09-29
Release date:2006-11-28
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:The Crystal Structure of Human N-acetyltransferase 1 mutant, F125S
To be Published
4LK4
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BU of 4lk4 by Molmil
Structure of Vibrio cholerae VesB protease
Descriptor: VESB protease
Authors:Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
Deposit date:2013-07-05
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional and Structural Characterization of Vibrio cholerae Extracellular Serine Protease B, VesB.
J.Biol.Chem., 289, 2014
4JOD
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BU of 4jod by Molmil
Crystal structure of human lysophosphatidic acid phosphatase type 6 complexed with Tris
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Lysophosphatidic acid phosphatase type 6
Authors:Li, J.
Deposit date:2013-03-18
Release date:2013-07-10
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structures and biochemical studies of human lysophosphatidic acid phosphatase type 6.
Protein Cell, 4, 2013
3DKH
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BU of 3dkh by Molmil
L559A mutant of Melanocarpus albomyces laccase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Hakulinen, N, Rouvinen, J.
Deposit date:2008-06-25
Release date:2009-07-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure
Febs J., 276, 2009
2IL3
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BU of 2il3 by Molmil
Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
Descriptor: Epsilon-class Glutathione S-transferase
Authors:Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
4LDG
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BU of 4ldg by Molmil
Crystal Structure of CpSET8 from Cryptosporidium, cgd4_370
Descriptor: MALONATE ION, Protein with a SET domain within carboxy region
Authors:Wernimont, A.K, Tempel, W, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, El Bakkouri, M, Structural Genomics Consortium (SGC)
Deposit date:2013-06-24
Release date:2013-07-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure of CpSET8 from Cryptosporidium, cgd4_370
To be Published
3DL9
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BU of 3dl9 by Molmil
Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2
Descriptor: (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ...
Authors:Strushkevich, N.V, Tempel, W, Gilep, A.A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-06-26
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.721 Å)
Cite:Crystal structure of CYP2R1 in complex with 1-alpha-hydroxy-vitamin D2.
To be Published
3DLM
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BU of 3dlm by Molmil
Crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1
Descriptor: Histone-lysine N-methyltransferase SETDB1
Authors:Amaya, M.F, Dombrovski, L, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2008-06-27
Release date:2008-08-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1.
To be Published
4JTE
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BU of 4jte by Molmil
Crystal structure of F114A mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis
Descriptor: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION
Authors:Allison, T.M, Cochrane, F.C, Jameson, G.B, Parker, E.J.
Deposit date:2013-03-23
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase.
Biochemistry, 52, 2013
2IMK
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BU of 2imk by Molmil
Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
Descriptor: Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE
Authors:Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
Deposit date:2006-10-02
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
3DKJ
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BU of 3dkj by Molmil
Crystal structure of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BENZAMIDE, Nicotinamide phosphoribosyltransferase
Authors:Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
Deposit date:2008-06-25
Release date:2009-08-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
4JUY
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BU of 4juy by Molmil
Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31
Descriptor: E3 ubiquitin-protein ligase RNF31, UNKNOWN ATOM OR ION
Authors:Dong, A, Hu, J, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2013-03-25
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31
To be Published
4LF6
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BU of 4lf6 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S rRNA, MAGNESIUM ION, NEOMYCIN, ...
Authors:Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T.
Deposit date:2013-06-26
Release date:2014-07-02
Method:X-RAY DIFFRACTION (3.3052 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
To be Published, 2013
3NCG
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BU of 3ncg by Molmil
Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1
Descriptor: 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, Calmodulin-domain protein kinase 1
Authors:Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-06-04
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii.
ACS Med Chem Lett, 1, 2010
4LGZ
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BU of 4lgz by Molmil
Structure of mouse 1-Pyrroline-5-Carboxylate Dehydrogenase (ALDH4A1) complexed with acetate
Descriptor: ACETIC ACID, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ...
Authors:Pemberton, T.A, Tanner, J.J.
Deposit date:2013-06-30
Release date:2013-08-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.675 Å)
Cite:Structural basis of substrate selectivity of Delta (1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): Semialdehyde chain length.
Arch.Biochem.Biophys., 538, 2013
3NH6
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BU of 3nh6 by Molmil
Nucleotide Binding Domain of human ABCB6 (apo structure)
Descriptor: ATP-binding cassette sub-family B member 6, mitochondrial, BETA-MERCAPTOETHANOL
Authors:Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W.
Deposit date:2010-06-14
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.
Acta Crystallogr.,Sect.D, 66, 2010
3DNX
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BU of 3dnx by Molmil
SPO1766 protein of unknown function from Silicibacter pomeroyi.
Descriptor: SODIUM ION, uncharacterized protein SPO1766
Authors:Osipiuk, J, Mulligan, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-07-02
Release date:2008-09-02
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:X-ray crystal structure of SPO1766 protein of unknown function from Silicibacter pomeroyi.
To be Published
4NAP
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BU of 4nap by Molmil
Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan
Descriptor: D-TRYPTOPHAN, Extracellular solute-binding protein, family 7
Authors:Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-10-22
Release date:2013-11-13
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
3NHF
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BU of 3nhf by Molmil
X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
Descriptor: 5,6,8-trimethoxy-4-methylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
Authors:Sturdy, M.
Deposit date:2010-06-14
Release date:2012-01-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
To be Published
4N7L
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BU of 4n7l by Molmil
Zinc Substituted Reaction Center M(L214H) Variant of Rhodobacter sphaeroides
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, FE (III) ION, ...
Authors:Hardjasa, A, Murphy, M.E.P.
Deposit date:2013-10-15
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and kinetic properties of Rhodobacter sphaeroides photosynthetic reaction centers containing exclusively Zn-coordinated bacteriochlorophyll as bacteriochlorin cofactors.
Biochim.Biophys.Acta, 1837, 2014
3NHR
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BU of 3nhr by Molmil
X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
Descriptor: 5,6,8-trimethoxy-1,4-dimethylquinolin-2(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
Authors:Sturdy, M.
Deposit date:2010-06-14
Release date:2012-01-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Crystallographic Structure Activity Relationship (SAR) of Casimiroin and its Analogs Bound to Human Quinone Reductase 2
To be Published
3DOO
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BU of 3doo by Molmil
Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis complexed with shikimate
Descriptor: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Shikimate dehydrogenase
Authors:Han, C, Hu, T, Wu, D, Zhou, J, Shen, X, Qu, D, Jiang, H.
Deposit date:2008-07-05
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis
Febs J., 276, 2009
3NIJ
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BU of 3nij by Molmil
The structure of UBR box (HIAA)
Descriptor: E3 ubiquitin-protein ligase UBR1, Peptide HIAA, ZINC ION
Authors:Choi, W.S, Jeong, B.-C, Lee, M.-R, Song, H.K.
Deposit date:2010-06-16
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases
Nat.Struct.Mol.Biol., 17, 2010
4N8G
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BU of 4n8g by Molmil
Crystal structure of a TRAP periplasmic solute binding protein from Chromohalobacter salexigens DSM 3043 (Csal_0660), Target EFI-501075, with bound D-alanine-D-alanine
Descriptor: CHLORIDE ION, D-ALANINE, SULFATE ION, ...
Authors:Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-10-17
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015

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