4NAP

Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan

Summary for 4NAP

• Entry DOI: 10.2210/pdb4nap/pdb
• Descriptor: Extracellular solute-binding protein, family 7, D-TRYPTOPHAN (3 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Desulfovibrio alaskensis
• Total number of polymer chains: 4
• Total formula weight: 141247.09

Authors

Vetting, M.W.,Al Obaidi, N.F.,Morisco, L.L.,Wasserman, S.R.,Sojitra, S.,Stead, M.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hillerich, B.,Love, J.,Seidel, R.D.,Imker, H.J.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2013-10-22, release date: 2013-11-13, Last modification date: 2015-02-25)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (2.3 Å)