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3PVO
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Monoclinic form of Human C-Reactive Protein
Descriptor: C-Reactive Protein, CALCIUM ION
Authors:Guillon, C, Mavoungou Bigouagou, U, Jeannin, P, Delneste, Y, Gouet, P.
Deposit date:2010-12-07
Release date:2012-01-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography.
Protein Pept.Lett., 22, 2014
2O0I
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BU of 2o0i by Molmil
crystal structure of the R185A mutant of the N-terminal domain of the Group B Streptococcus Alpha C protein
Descriptor: C protein alpha-antigen
Authors:Hogle, J.M, Filman, D.J, Baron, M.J, Madoff, L.C, Iglesias, A.
Deposit date:2006-11-27
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells.
J.Biol.Chem., 282, 2007
5FGB
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BU of 5fgb by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC33.4
Descriptor: Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, GLYCEROL, ...
Authors:Girard-Blanc, C, Rey, F.A, Krey, T.
Deposit date:2015-12-20
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus.
J.Virol., 90, 2016
5FGC
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Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC33.8
Descriptor: Anti-HCV E2 Fab HC33.8 heavy chain, Anti-HCV E2 Fab HC33.8 light chain, Genome polyprotein
Authors:Girard-Blanc, C, Rey, F.A, Krey, T.
Deposit date:2015-12-20
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus.
J.Virol., 90, 2016
2XRU
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BU of 2xru by Molmil
AURORA-A T288E COMPLEXED WITH PHA-828300
Descriptor: 3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMINO)-N-[(1R)-1-PHENYLPROPYL]-1H-THIENO[3,2-C]PYRAZOLE-5-CARBOXAMIDE, SERINE/THREONINE-PROTEIN KINASE 6
Authors:Bindi, S, Fancelli, D, Alli, C, Berta, D, Bertrand, J.A, Cameron, A.D, Cappella, P, Carpinelli, P, Cervi, G, Croci, W, D'Anello, M, Forte, B, LauraGiorgini, M, Marsiglio, A, Moll, J, Pesenti, E, Pittala, V, Pulici, M, Riccardi-Sirtori, F, Roletto, F, Soncini, C, Storici, P, Varasi, M, Volpi, D, Zugnoni, P, Vianello, P.
Deposit date:2010-09-22
Release date:2010-09-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Thieno[3,2-C]Pyrazoles: A Novel Class of Aurora Inhibitors with Favorable Antitumor Activity.
Bioorg.Med.Chem., 18, 2010
1HV2
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BU of 1hv2 by Molmil
SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
Descriptor: ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
Authors:Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H.
Deposit date:2001-01-05
Release date:2001-09-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
7B3Q
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Crystal structure of c-MET bound by compound 1
Descriptor: 1-(phenylmethyl)-5~{H}-pyrrolo[3,2-c]pyridin-4-one, Hepatocyte growth factor receptor, SULFATE ION
Authors:Collie, G.W.
Deposit date:2020-12-01
Release date:2020-12-09
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Targeting the Folded P-Loop Conformation of c-MET.
Acs Med.Chem.Lett., 12, 2021
1GX7
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Best model of the electron transfer complex between cytochrome c3 and [Fe]-hydrogenase
Descriptor: 1,3-PROPANEDITHIOL, CARBON MONOXIDE, CYANIDE ION, ...
Authors:Elantak, L, Morelli, X, Bornet, O, Hatchikian, C, Czjzek, M, Dolla, A, Guerlesquin, F.
Deposit date:2002-03-28
Release date:2003-07-31
Last modified:2019-11-27
Method:SOLUTION NMR, THEORETICAL MODEL
Cite:The Cytochrome C(3)-[Fe]-Hydrogenase Electron-Transfer Complex: Structural Model by NMR Restrained Docking
FEBS Lett., 548, 2003
246D
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BU of 246d by Molmil
STRUCTURE OF THE PURINE-PYRIMIDINE ALTERNATING RNA DOUBLE HELIX, R(GUAUAUA)D(C) , WITH A 3'-TERMINAL DEOXY RESIDUE
Descriptor: DNA/RNA (5'-R(*GP*UP*AP*UP*AP*UP*AP*)-D(*C)-3'), SODIUM ION
Authors:Wahl, M.C, Ban, C, Sekharudu, C, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1996-01-25
Release date:1996-08-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the purine-pyrimidine alternating RNA double helix, r(GUAUAUA)d(C), with a 3'-terminal deoxy residue.
Acta Crystallogr.,Sect.D, 52, 1996
2AWW
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Synapse associated protein 97 PDZ2 domain variant C378G with C-terminal GluR-A peptide
Descriptor: 18-residue C-terminal peptide from glutamate receptor, ionotropic, AMPA1, ...
Authors:Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K.
Deposit date:2005-09-02
Release date:2006-08-29
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
2A4J
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BU of 2a4j by Molmil
Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein
Descriptor: 17-mer peptide P1-XPC from DNA-repair protein complementing XP-C cells, Centrin 2
Authors:Yang, A, Miron, S, Mouawad, L, Duchambon, P, Blouquit, Y, Craescu, C.T.
Deposit date:2005-06-29
Release date:2005-07-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein (XPC) from nuclear excision repair.
Biochemistry, 45, 2006
7S9Z
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BU of 7s9z by Molmil
Helicobacter Hepaticus CcsBA Closed Conformation
Descriptor: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
Authors:Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
Deposit date:2021-09-21
Release date:2021-12-22
Last modified:2022-01-12
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
7S9Y
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BU of 7s9y by Molmil
Helicobacter Hepaticus CcsBA Open Conformation
Descriptor: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
Authors:Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
Deposit date:2021-09-21
Release date:2021-12-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
6I7R
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BU of 6i7r by Molmil
Structure of pVHL-elongin B-elongin C (VCB) in complex with hydroxylated-HIF-2alpha (523-542) in the P43212 form
Descriptor: Elongin-B, Elongin-C, Endothelial PAS domain-containing protein 1, ...
Authors:Chowdhury, R, Aguilera, L.S, Schofield, C.J.
Deposit date:2018-11-17
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:HIF-2alpha-pVHL-elongin B-elongin C complex
To Be Published
6I7Q
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BU of 6i7q by Molmil
Structure of pVHL-elongin B-elongin C (VCB) in complex with hydroxylated-HIF-2alpha (523-542) in the C2221 form
Descriptor: Elongin-B, Elongin-C, Endothelial PAS domain-containing protein 1, ...
Authors:Chowdhury, R, Aguilera, L.S, Schofield, C.J.
Deposit date:2018-11-17
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:HIF-2alpha-pVHL-elongin B-elongin C complex
To Be Published
4XXL
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BU of 4xxl by Molmil
Crystal structure of Class 1 cytochrome MtoD from Sideroxydans lithotrophicus ES-1
Descriptor: Cytochrome c class I, HEME C
Authors:Beckwith, C.R, Edwards, M.J, Clarke, T.
Deposit date:2015-01-30
Release date:2015-04-15
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Characterization of MtoD from Sideroxydans lithotrophicus: a cytochrome c electron shuttle used in lithoautotrophic growth.
Front Microbiol, 6, 2015
4WJY
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Esherichia coli nitrite reductase NrfA H264N
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cytochrome c-552, ...
Authors:Clarke, T.A, Edwards, M.J, Lockwood, C.W.J.
Deposit date:2014-10-01
Release date:2015-03-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Resolution of key roles for the distal pocket histidine in cytochrome C nitrite reductases.
J.Am.Chem.Soc., 137, 2015
8EBN
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BU of 8ebn by Molmil
Structure of KLHDC2-EloB/C tetrameric assembly
Descriptor: Elongin-B, Elongin-C, Kelch domain-containing protein 2
Authors:Scott, D.C, Schulman, B.A.
Deposit date:2022-08-31
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Mol.Cell, 83, 2023
3LKH
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BU of 3lkh by Molmil
Inhibitors of Hepatitis C Virus Polymerase: Synthesis and Characterization of Novel 6-Fluoro-N-[2-Hydroxy-1(S)-Benzamides
Descriptor: 2-(2-{[(1S)-1-benzyl-2-hydroxyethyl]amino}-2-oxoethoxy)-N-butyl-6-fluoro-N-methylbenzamide, RNA-directed RNA polymerase
Authors:Lesburg, C.A.
Deposit date:2010-01-27
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides.
Bioorg.Med.Chem.Lett., 20, 2010
3KQN
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BU of 3kqn by Molmil
Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQU
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*T*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inaugural Article: Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
6XA2
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Structure of the tirandamycin C-bound P450 monooxygenase TamI
Descriptor: (3E)-3-{(2E,4E,6R)-1-hydroxy-4-methyl-6-[(1R,3R,4S,5R)-1,4,8-trimethyl-2,9-dioxabicyclo[3.3.1]non-7-en-3-yl]hepta-2,4-dien-1-ylidene}-2H-pyrrole-2,4(3H)-dione, PROTOPORPHYRIN IX CONTAINING FE, TamI
Authors:Newmister, S.A, Srivastava, K.R, Espinoza, R.V, Haatveit, K.C, Khatri, Y, Martini, R.M, Garcia-Borras, M, Podust, L.M, Houk, K.N, Sherman, D.H.
Deposit date:2020-06-03
Release date:2021-06-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Molecular Basis of Iterative C─H Oxidation by TamI, a Multifunctional P450 monooxygenase from the Tirandamycin Biosynthetic Pathway.
Acs Catalysis, 10, 2020
3KQH
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Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Descriptor: 5'-D(*AP*AP*AP*AP*AP*A)-3', Serine protease/NTPase/helicase NS3
Authors:Gu, M, Rice, C.M.
Deposit date:2009-11-17
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M97
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BU of 3m97 by Molmil
Structure of the soluble domain of cytochrome c552 with its flexible linker segment from Paracoccus denitrificans
Descriptor: Cytochrome c-552, HEME C, ZINC ION
Authors:Rajendran, C, Ermler, U, Ludwig, B, Michel, H.
Deposit date:2010-03-20
Release date:2010-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.332 Å)
Cite:Structure at 1.5 A resolution of cytochrome c(552) with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans.
Acta Crystallogr.,Sect.D, 66, 2010
1BT7
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THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES
Descriptor: NS3 SERINE PROTEASE, ZINC ION
Authors:Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R.
Deposit date:1998-09-01
Release date:1999-06-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism.
J.Mol.Biol., 289, 1999

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