PDB: 283 resultsInfo pagesStatus searchChemie searchBIRD

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8EQQ	Crystal structure of E.coli DsbA mutant E37A Descriptor: CITRATE ANION, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2022-10-09 Release date: 2023-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.13 Å) Cite: A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
8EQO	Crystal structure of E.coli DsbA mutant K58A Descriptor: COPPER (II) ION, GLYCEROL, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2022-10-08 Release date: 2023-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.62 Å) Cite: A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
8EQP	Crystal structure of E.coli DsbA mutant E24A/E37A/K58A Descriptor: CITRATE ANION, GLYCEROL, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2022-10-09 Release date: 2023-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
8EQR	Crystal structure of E.coli DsbA mutant E24A Descriptor: DI(HYDROXYETHYL)ETHER, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2022-10-09 Release date: 2023-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.29 Å) Cite: A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA. Antioxidants, 12, 2023
2IMF	2-Hydroxychromene-2-carboxylate Isomerase: a Kappa Class Glutathione-S-Transferase from Pseudomonas putida Descriptor: 2-hydroxychromene-2-carboxylate isomerase, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, 4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID, ... Authors: Thompson, L.C, Ladner, J.E, Codreanu, S.G, Harp, J, Gilliland, G.L, Armstrong, R.N. Deposit date: 2006-10-04 Release date: 2007-06-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: 2-Hydroxychromene-2-carboxylic acid isomerase: a kappa class glutathione transferase from Pseudomonas putida. Biochemistry, 46, 2007
5CP1	Crystal structure of C239S mutant of a novel disulfide oxidoreductase from Deinococcus radiodurans Descriptor: 1,2-ETHANEDIOL, ACETATE ION, FrnE protein, ... Authors: Bihani, S.C, Panicker, L, Kumar, V. Deposit date: 2015-07-21 Release date: 2016-07-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Crystal structure of a novel disulfide oxidoreductase from Deinococcus radiodurans To Be Published
5COH	Crystal structure of a novel disulfide oxidoreductase from Deinococcus radiodurans crystallized in presence of beta-mercaptoethanol Descriptor: FrnE protein Authors: Bihani, S.C, Panicker, L, Kumar, V. Deposit date: 2015-07-20 Release date: 2016-07-20 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.801 Å) Cite: drFrnE Represents a Hitherto Unknown Class of Eubacterial Cytoplasmic Disulfide Oxido-Reductases. Antioxid. Redox Signal., 28, 2018
2IJY	NMR structure ensemble for the reduced DsbA disulphide oxidoreductase from Vibrio Cholerae Descriptor: Thiol:disulfide interchange protein dsbA Authors: Horne, J.H, Velkov, T, Scanlon, M.J. Deposit date: 2006-10-02 Release date: 2007-07-17 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae-a (15)N - (1)H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA. J.Mol.Biol., 371, 2007
2IN3	Crystal structure of a putative protein disulfide isomerase from Nitrosomonas europaea Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Hypothetical protein, ... Authors: Cuff, M.E, Skarina, T, Onopriyenko, O, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2006-10-05 Release date: 2006-11-21 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of a putative protein disulfide isomerase from Nitrosomonas europaea To be Published
5DCH	Crystal structure of Pseudomonas aeruginosa DsbA E82I in complex with MIPS-0000851 (3-[(2-METHYLBENZYL)SULFANYL]-4H-1,2,4-TRIAZOL-4-AMINE) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, GLYCEROL, ... Authors: McMahon, R.M, Martin, J.L. Deposit date: 2015-08-24 Release date: 2016-10-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.447 Å) Cite: Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
5E59	Crystal structure of reduced state of a novel disulfide oxidoreductase from Deinococcus radiodurans Descriptor: FrnE protein, GLYCEROL Authors: Bihani, S.C, Panicker, L, Kumar, V. Deposit date: 2015-10-08 Release date: 2016-10-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: drFrnE Represents a Hitherto Unknown Class of Eubacterial Cytoplasmic Disulfide Oxido-Reductases. Antioxid. Redox Signal., 28, 2018
7L7C	Crystal Structure of EcDsbA in a complex with 2-(6-(3-Methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Ilyichova, O.V, Scanlon, M.J. Deposit date: 2020-12-28 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
7L76	Crystal Structure of EcDsbA in a complex with 2-(6-Phenylbenzofuran-3-yl)acetic acid Descriptor: (6-phenyl-1-benzofuran-3-yl)acetic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Ilyichova, O.V, Scanlon, M.J. Deposit date: 2020-12-26 Release date: 2021-08-11 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
7LHP	Crystal Structure of EcDsbA in a complex with methyl 2-(6-bromo-2-phenylbenzofuran-3-yl)acetate Descriptor: (6-bromo-2-phenyl-1-benzofuran-3-yl)acetic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Ilyichova, O.V, Scanlon, M.J. Deposit date: 2021-01-26 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
7LUI	Crystal structure of Vibrio cholerae DsbA in complex with bile salt taurocholate Descriptor: GLYCEROL, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2021-02-22 Release date: 2021-12-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials. Chemmedchem, 17, 2022
7LUH	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment bromophenoxy propanamide Descriptor: (2~{R})-2-(4-bromanylphenoxy)propanamide, Thiol:disulfide interchange protein Authors: Petit, G.A, Martin, J.L, McMahon, R.M. Deposit date: 2021-02-22 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LSM	Crystal structure of E.coli DsbA in complex with bile salt taurocholate Descriptor: DI(HYDROXYETHYL)ETHER, TAUROCHOLIC ACID, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2021-02-18 Release date: 2021-12-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.786 Å) Cite: Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials. Chemmedchem, 17, 2022
7LUJ	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment 4-methoxy-N-phenylbenzenesulfonamide Descriptor: 4-methoxy-~{N}-phenyl-benzenesulfonamide, SULFATE ION, Thiol:disulfide interchange protein Authors: Petit, G.A, Martin, J.L, McMahon, R.M. Deposit date: 2021-02-22 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
1ACV	DSBA MUTANT H32S Descriptor: DSBA Authors: Guddat, L.W, Martin, J.L. Deposit date: 1997-02-10 Release date: 1997-10-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
1AC1	DSBA MUTANT H32L Descriptor: DSBA Authors: Guddat, L.W, Martin, J.L. Deposit date: 1997-02-10 Release date: 1997-10-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
1BED	STRUCTURE OF DISULFIDE OXIDOREDUCTASE Descriptor: DSBA OXIDOREDUCTASE Authors: Hu, S.-H, Martin, J.L. Deposit date: 1996-09-16 Release date: 1997-10-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae. J.Mol.Biol., 268, 1997
1BQ7	DSBA MUTANT P151A, ROLE OF THE CIS-PROLINE IN THE ACTIVE SITE OF DSBA Descriptor: PROTEIN (DISULFIDE OXIDOREDUCTASE) Authors: Charbonnier, J.-B, Stura, E.A. Deposit date: 1998-08-21 Release date: 1999-08-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: On the role of the cis-proline residue in the active site of DsbA. Protein Sci., 8, 1999
1A2M	OXIDIZED DSBA AT 2.7 ANGSTROMS RESOLUTION, CRYSTAL FORM III Descriptor: DISULFIDE BOND FORMATION PROTEIN Authors: Martin, J.L, Guddat, L.W. Deposit date: 1998-01-06 Release date: 1998-07-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization. Structure, 6, 1998
1A2J	OXIDIZED DSBA CRYSTAL FORM II Descriptor: DISULFIDE BOND FORMATION PROTEIN Authors: Martin, J.L, Guddat, L.W. Deposit date: 1998-01-06 Release date: 1998-09-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization. Structure, 6, 1998
1A23	SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, MINIMIZED AVERAGE STRUCTURE Descriptor: DSBA Authors: Schirra, H.J, Renner, C, Czisch, M, Huber-Wunderlich, M, Holak, T.A, Glockshuber, R. Deposit date: 1998-01-15 Release date: 1998-09-16 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of reduced DsbA from Escherichia coli in solution. Biochemistry, 37, 1998

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