7YCA
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![BU of 7yca by Molmil](/molmil-images/mine/7yca) | Cryo-EM structure of the PSI-LHCI-Lhcp supercomplex from Ostreococcus tauri | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z. | Deposit date: | 2022-07-01 | Release date: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers. Elife, 12, 2023
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7YC9
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![BU of 7yc9 by Molmil](/molmil-images/mine/7yc9) | Co-crystal structure of BTK kinase domain with inhibitor | Descriptor: | (7~{S})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, 1,2-ETHANEDIOL, Tyrosine-protein kinase BTK | Authors: | Zhou, X. | Deposit date: | 2022-07-01 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases. J.Med.Chem., 66, 2023
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7YC7
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![BU of 7yc7 by Molmil](/molmil-images/mine/7yc7) | Dark, fully reduced structure of the MmCPDII-DNA complex as produced at SwissFEL | Descriptor: | CPD photolesion containing DNA, Deoxyribodipyrimidine photo-lyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Maestre-Reyna, M, Wang, P.-H, Nango, E, Hosokawa, Y, Saft, M, Furrer, A, Yang, C.-H, Ngura Putu, E.P.G, Wu, W.-J, Emmerich, H.-J, Engilberge, S, Caramello, N, Wranik, M, Glover, H.L, Franz-Badur, S, Wu, H.-Y, Lee, C.-C, Huang, W.-C, Huang, K.-F, Chang, Y.-K, Liao, J.-H, Weng, J.-H, Gad, W, Chang, C.-W, Pang, A.H, Gashi, D, Beale, E, Ozerov, D, Milne, C, Cirelli, C, Bacellar, C, Sugahara, M, Owada, S, Joti, Y, Yamashita, A, Tanaka, R, Tanaka, T, Luo, F.J, Tono, K, Kiontke, S, Spadaccini, R, Royant, A, Yamamoto, J, Iwata, S, Standfuss, J, Essen, L.-O, Bessho, Y, Tsai, M.-D. | Deposit date: | 2022-07-01 | Release date: | 2023-11-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Visualizing the DNA repair process by a photolyase at atomic resolution. Science, 382, 2023
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7YC4
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![BU of 7yc4 by Molmil](/molmil-images/mine/7yc4) | Acetylesterase (LgEstI) F207A | Descriptor: | Alpha/beta hydrolase | Authors: | Do, H, Lee, J.H. | Deposit date: | 2022-06-30 | Release date: | 2023-06-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and biochemical analysis of acetylesterase (LgEstI) from Lactococcus garvieae. Plos One, 18, 2023
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7YC3
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![BU of 7yc3 by Molmil](/molmil-images/mine/7yc3) | Crystal structure of FGFR4 kinase domain with 10t | Descriptor: | 6-bromanyl-~{N}-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-1-(2-morpholin-4-ylethyl)pyrrolo[3,2-b]pyridine-3-carboxamide, Fibroblast growth factor receptor 4, GLYCEROL, ... | Authors: | Chen, X.J, Lin, Q.M, Chen, Y.H. | Deposit date: | 2022-06-30 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.987 Å) | Cite: | Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2- b ]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors. J.Med.Chem., 65, 2022
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7YC1
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![BU of 7yc1 by Molmil](/molmil-images/mine/7yc1) | Crystal structure of FGFR4 kinase domain with 10d | Descriptor: | Fibroblast growth factor receptor 4, GLYCEROL, SULFATE ION, ... | Authors: | Chen, X.J, Lin, Q.M, Chen, Y.H. | Deposit date: | 2022-06-30 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.535 Å) | Cite: | Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2- b ]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors. J.Med.Chem., 65, 2022
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7YC0
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![BU of 7yc0 by Molmil](/molmil-images/mine/7yc0) | Acetylesterase (LgEstI) W.T. | Descriptor: | ACETATE ION, Alpha/beta hydrolase, CHLORIDE ION | Authors: | Do, H, Lee, J.H. | Deposit date: | 2022-06-30 | Release date: | 2023-06-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and biochemical analysis of acetylesterase (LgEstI) from Lactococcus garvieae. Plos One, 18, 2023
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7YBU
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![BU of 7ybu by Molmil](/molmil-images/mine/7ybu) | Human propionyl-coenzyme A carboxylase | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase alpha chain, mitochondrial, ... | Authors: | Su, J.Y, Liu, D.S. | Deposit date: | 2022-06-29 | Release date: | 2023-07-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Human propionyl-coenzyme A carboxylase To Be Published
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7YBG
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![BU of 7ybg by Molmil](/molmil-images/mine/7ybg) | |
7YBD
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![BU of 7ybd by Molmil](/molmil-images/mine/7ybd) | Crystal structure of sliding DNA clamp of Clostridioides difficile | Descriptor: | Beta sliding clamp, TRIETHYLENE GLYCOL | Authors: | Hishiki, A, Okazaki, S, Hara, K, Hashimoto, H. | Deposit date: | 2022-06-29 | Release date: | 2022-10-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of the sliding DNA clamp from the Gram-positive anaerobic bacterium Clostridioides difficile. J.Biochem., 173, 2022
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7YBC
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![BU of 7ybc by Molmil](/molmil-images/mine/7ybc) | |
7YBB
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![BU of 7ybb by Molmil](/molmil-images/mine/7ybb) | |
7YB9
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![BU of 7yb9 by Molmil](/molmil-images/mine/7yb9) | |
7YB8
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![BU of 7yb8 by Molmil](/molmil-images/mine/7yb8) | |
7YB7
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![BU of 7yb7 by Molmil](/molmil-images/mine/7yb7) | anti-apoptotic protein BCL-2-M12 | Descriptor: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1, N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide, cp2 peptide | Authors: | Li, F.W, Liu, C, Wu, D.L. | Deposit date: | 2022-06-29 | Release date: | 2023-11-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy. Nat Commun, 15, 2024
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7YB3
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![BU of 7yb3 by Molmil](/molmil-images/mine/7yb3) | SufS with D-cysteine for 1 min | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-06-28 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Snapshots of thiazolidine fomration of PLP-dependent enzyme SufS to be published
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7YB2
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![BU of 7yb2 by Molmil](/molmil-images/mine/7yb2) | Crystal Structure of anthrol reductase (CbAR) in complex with NADP+ and emodin | Descriptor: | 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Hou, X.D, Rao, Y.J. | Deposit date: | 2022-06-28 | Release date: | 2023-06-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and beta-halohydrins. Nat Commun, 14, 2023
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7YB1
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![BU of 7yb1 by Molmil](/molmil-images/mine/7yb1) | Crystal Structure of anthrol reductase (CbAR) in complex with NADP+ | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Versicolorin reductase | Authors: | Hou, X.D, Rao, Y.J. | Deposit date: | 2022-06-28 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and beta-halohydrins. Nat Commun, 14, 2023
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7YAZ
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![BU of 7yaz by Molmil](/molmil-images/mine/7yaz) | Crystal structure of ZAK in complex with compound YH-186 | Descriptor: | Mitogen-activated protein kinase kinase kinase MLT, ~{N}-[2,4-bis(fluoranyl)-3-[4-[3-[(3~{S})-1-propanoylpyrrolidin-3-yl]oxy-1~{H}-pyrazolo[3,4-b]pyridin-5-yl]-1,2,3-triazol-1-yl]phenyl]-3-phenyl-benzenesulfonamide | Authors: | Kong, L.L, Yun, C.H. | Deposit date: | 2022-06-28 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov). J.Med.Chem., 66, 2023
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7YAX
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![BU of 7yax by Molmil](/molmil-images/mine/7yax) | HYDROXYNITRILE LYASE FROM THE MILLIPEDE, | Descriptor: | CHLORIDE ION, Hydroxynitrile lyase, SULFATE ION | Authors: | Chaikaew, S, Watanabe, Y, Zheng, D, Motojima, F, Asano, Y. | Deposit date: | 2022-06-28 | Release date: | 2024-01-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure-Based Site-Directed Mutagenesis of Hydroxynitrile Lyase from Cyanogenic Millipede, Oxidus gracilis for Hydrocyanation and Henry Reactions. Chembiochem, 25, 2024
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7YAW
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![BU of 7yaw by Molmil](/molmil-images/mine/7yaw) | Crystal structure of ZAK in complex with compound YH-180 | Descriptor: | Mitogen-activated protein kinase kinase kinase MLT, ~{N}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | Authors: | Kong, L.L, Yun, C.H. | Deposit date: | 2022-06-28 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Rational Design of Covalent Kinase Inhibitors by an Integrated Computational Workflow (Kin-Cov). J.Med.Chem., 66, 2023
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7YAS
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![BU of 7yas by Molmil](/molmil-images/mine/7yas) | HYDROXYNITRILE LYASE, LOW TEMPERATURE NATIVE STRUCTURE | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, PROTEIN (HYDROXYNITRILE LYASE), ... | Authors: | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | Deposit date: | 1999-03-15 | Release date: | 1999-10-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Sci., 8, 1999
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7YAR
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![BU of 7yar by Molmil](/molmil-images/mine/7yar) | ZIKV_Fab_G9E | Descriptor: | E protein, M protein, heavy chain, ... | Authors: | Shu, B, Thiam-Seng, N, Lok, S. | Deposit date: | 2022-06-28 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus. Plos Pathog., 19, 2023
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7YAM
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![BU of 7yam by Molmil](/molmil-images/mine/7yam) | CryoEM structure of SPCA1a in E2P state | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | Authors: | Chen, Z, Watanabe, S, Inaba, K. | Deposit date: | 2022-06-28 | Release date: | 2023-03-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAJ
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![BU of 7yaj by Molmil](/molmil-images/mine/7yaj) | CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1 | Descriptor: | Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ... | Authors: | Chen, Z, Watanabe, S, Inaba, K. | Deposit date: | 2022-06-28 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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