1MD3
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![BU of 1md3 by Molmil](/molmil-images/mine/1md3) | A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase | Authors: | Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. | Deposit date: | 2002-08-06 | Release date: | 2002-08-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1 J.Biol.Chem., 278, 2003
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4ODC
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![BU of 4odc by Molmil](/molmil-images/mine/4odc) | Crystal structure of Trematomus bernacchii hemoglobin in a partially cyanided state | Descriptor: | CYANIDE ION, GLYCEROL, Hemoglobin subunit alpha, ... | Authors: | Mazzarella, L, Merlino, A, Vitagliano, L, Vergara, A. | Deposit date: | 2014-01-10 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin RSC ADV, 4, 2014
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5VFT
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![BU of 5vft by Molmil](/molmil-images/mine/5vft) | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... | Authors: | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | Deposit date: | 2017-04-09 | Release date: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
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5KCU
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![BU of 5kcu by Molmil](/molmil-images/mine/5kcu) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-ethyl, alpha-naphthyl OBHS-N derivative | Descriptor: | (1S,2R,4S)-N-ethyl-5,6-bis(4-hydroxyphenyl)-N-(naphthalen-2-yl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, NCOA2 | Authors: | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Dharmarajan, V, Goswami, D, Kastrati, I, Novick, S, Nowak, J, Zhou, H.B, Boonmuen, N, Zhao, Y, Min, J, Frasor, J, Katzenellenbogen, B.S, Griffin, P.R, Katzenellenbogen, J.A, Nettles, K.W. | Deposit date: | 2016-06-07 | Release date: | 2016-11-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nat. Chem. Biol., 13, 2017
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1MH9
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![BU of 1mh9 by Molmil](/molmil-images/mine/1mh9) | Crystal Structure Analysis of deoxyribonucleotidase | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, deoxyribonucleotidase | Authors: | Rinaldo-Matthis, A, Rampazzo, C, Reichard, P, Bianchi, V, Nordlund, P. | Deposit date: | 2002-08-19 | Release date: | 2002-10-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a human mitochondrial deoxyribonucleotidase. Nat.Struct.Biol., 9, 2002
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1MI0
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![BU of 1mi0 by Molmil](/molmil-images/mine/1mi0) | Crystal Structure of the redesigned protein G variant NuG2 | Descriptor: | immunoglobulin-binding protein G | Authors: | Nauli, S, Kuhlman, B, Le Trong, I, Stenkamp, R.E, Teller, D.C, Baker, D. | Deposit date: | 2002-08-21 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2 Biochemistry, 11, 2002
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1MHN
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![BU of 1mhn by Molmil](/molmil-images/mine/1mhn) | |
1MIC
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![BU of 1mic by Molmil](/molmil-images/mine/1mic) | |
1MHS
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![BU of 1mhs by Molmil](/molmil-images/mine/1mhs) | Model of Neurospora crassa proton ATPase | Descriptor: | Plasma Membrane ATPase | Authors: | Kuhlbrandt, W. | Deposit date: | 2002-08-21 | Release date: | 2002-09-18 | Last modified: | 2024-02-14 | Method: | ELECTRON CRYSTALLOGRAPHY (8 Å) | Cite: | Structure, mechanism and regulation of the Neurospora plasma membrane H+-ATPase Science, 297, 2002
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1MK2
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![BU of 1mk2 by Molmil](/molmil-images/mine/1mk2) | SMAD3 SBD complex | Descriptor: | ACETIC ACID, Madh-interacting protein, SMAD 3 | Authors: | Qin, B.Y, Lam, S.S, Correia, J.J, Lin, K. | Deposit date: | 2002-08-28 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control Genes Dev., 16, 2002
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2FTQ
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![BU of 2ftq by Molmil](/molmil-images/mine/2ftq) | E. coli thymidylate synthase at 1.8 A resolution | Descriptor: | PHOSPHATE ION, SULFATE ION, Thymidylate synthase | Authors: | Montfort, W.R, Roberts, S.A. | Deposit date: | 2006-01-24 | Release date: | 2006-05-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Subtle Conformational Differences between Escherichia coli Thymidylate Synthase and Specific Mutants of this Enzyme To be Published
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5D5U
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![BU of 5d5u by Molmil](/molmil-images/mine/5d5u) | Crystal structure of human Hsf1 with HSE DNA | Descriptor: | Heat shock Element DNA, Heat shock factor protein 1 | Authors: | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | Deposit date: | 2015-08-11 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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2GGK
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1MNY
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![BU of 1mny by Molmil](/molmil-images/mine/1mny) | Dimethyl propionate ester heme-containing cytochrome b5 | Descriptor: | DIMETHYL PROPIONATE ESTER HEME, cytochrome b5 | Authors: | Banci, L, Bertini, I, Branchini, B.R, Hajieva, P, Spyroulias, G.A, Turano, P. | Deposit date: | 2002-09-06 | Release date: | 2002-11-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Dimethyl propionate ester heme-containing cytochrome b5: structure and stability. J.BIOL.INORG.CHEM., 6, 2001
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1MLA
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![BU of 1mla by Molmil](/molmil-images/mine/1mla) | THE ESCHERICHIA COLI MALONYL-COA:ACYL CARRIER PROTEIN TRANSACYLASE AT 1.5-ANGSTROMS RESOLUTION. CRYSTAL STRUCTURE OF A FATTY ACID SYNTHASE COMPONENT | Descriptor: | MALONYL-COENZYME A ACYL CARRIER PROTEIN TRANSACYLASE | Authors: | Serre, L, Verbree, E.C, Dauter, Z, Stuitje, A.R, Derewenda, Z.S. | Deposit date: | 1995-01-25 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component. J.Biol.Chem., 270, 1995
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1MP2
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![BU of 1mp2 by Molmil](/molmil-images/mine/1mp2) | Structure of MT-ADPRase (Apoenzyme), a Nudix hydrolase from Mycobacterium tuberculosis | Descriptor: | ADPR pyrophosphatase | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-11 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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7R6H
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![BU of 7r6h by Molmil](/molmil-images/mine/7r6h) | RHCC in complex with o-carborane | Descriptor: | Tetrabrachion, ortho-carborane | Authors: | Heide, F, McDougall, M, Stetefeld, J. | Deposit date: | 2021-06-22 | Release date: | 2021-07-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Boron rich nanotube drug carrier system is suited for boron neutron capture therapy. Sci Rep, 11, 2021
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1MLV
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![BU of 1mlv by Molmil](/molmil-images/mine/1mlv) | Structure and Catalytic Mechanism of a SET Domain Protein Methyltransferase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ribulose-1,5 biphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Trievel, R.C, Beach, B.M, Dirk, L.M.A, Houtz, R.L, Hurley, J.H. | Deposit date: | 2002-08-30 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and catalytic mechanism of a SET domain protein methyltransferase. Cell(Cambridge,Mass.), 111, 2002
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1MMO
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![BU of 1mmo by Molmil](/molmil-images/mine/1mmo) | CRYSTAL STRUCTURE OF A BACTERIAL NON-HAEM IRON HYDROXYLASE THAT CATALYSES THE BIOLOGICAL OXIDATION OF METHANE | Descriptor: | ACETIC ACID, FE (III) ION, METHANE MONOOXYGENASE HYDROLASE (ALPHA CHAIN), ... | Authors: | Rosenzweig, A.C, Frederick, C.A, Lippard, S.J, Nordlund, P. | Deposit date: | 1994-02-22 | Release date: | 1995-02-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane. Nature, 366, 1993
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1MPW
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![BU of 1mpw by Molmil](/molmil-images/mine/1mpw) | Molecular Recognition in (+)-a-Pinene Oxidation by Cytochrome P450cam | Descriptor: | (+)-alpha-Pinene, CYTOCHROME P450CAM, POTASSIUM ION, ... | Authors: | Bell, S.G, Chen, X, Sowden, R.J, Xu, F, Willams, J.N, Wong, L.-L, Rao, Z. | Deposit date: | 2002-09-13 | Release date: | 2002-10-09 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam J.Am.Chem.Soc., 125, 2003
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1MQA
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![BU of 1mqa by Molmil](/molmil-images/mine/1mqa) | Crystal structure of high affinity alphaL I domain in the absence of ligand or metal | Descriptor: | Integrin alpha-L | Authors: | Shimaoka, T, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, Zhang, R, Takagi, J, Wang, J.-H, Springer, T.A. | Deposit date: | 2002-09-15 | Release date: | 2003-01-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003
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1MQE
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![BU of 1mqe by Molmil](/molmil-images/mine/1mqe) | Structure of the MT-ADPRase in complex with gadolidium and ADP-ribose, a Nudix enzyme | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase, GADOLINIUM ION | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-16 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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8DVN
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![BU of 8dvn by Molmil](/molmil-images/mine/8dvn) | Crystal structure of LRP6 E3E4 in complex with disulfide constrained peptide E3.10 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Thakur, A.K, Liau, N.P.D, Sudhamsu, J, Hannoush, R.N. | Deposit date: | 2022-07-29 | Release date: | 2023-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/ beta-Catenin Signaling via LRP6 Coreceptor Clustering. Acs Chem.Biol., 18, 2023
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1MFN
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![BU of 1mfn by Molmil](/molmil-images/mine/1mfn) | SOLUTION NMR STRUCTURE OF LINKED CELL ATTACHMENT MODULES OF MOUSE FIBRONECTIN CONTAINING THE RGD AND SYNERGY REGIONS, 20 STRUCTURES | Descriptor: | FIBRONECTIN | Authors: | Copie, V, Tomita, Y, Akiyama, S.K, Aota, S, Yamada, K.M, Venable, R.M, Pastor, R.W, Krueger, S, Torchia, D.A. | Deposit date: | 1998-01-27 | Release date: | 1998-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure. J.Mol.Biol., 277, 1998
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7REC
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![BU of 7rec by Molmil](/molmil-images/mine/7rec) | Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII alpha hub bound to 5-HDC | Descriptor: | 5-hydroxydiclofenac, Calcium/calmodulin-dependent protein kinase type II subunit alpha, SODIUM ION | Authors: | McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J. | Deposit date: | 2021-07-12 | Release date: | 2021-07-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | GHB analogs confer neuroprotection through specific interaction with the CaMKII alpha hub domain. Proc.Natl.Acad.Sci.USA, 118, 2021
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