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3H0H
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human Fyn SH3 domain R96I mutant, crystal form I
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn, TETRAETHYLENE GLYCOL
Authors:Dumas, C, Strub, M.-P, Arold, S.T.
Deposit date:2009-04-09
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
4ESR
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BU of 4esr by Molmil
Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors
Descriptor: DI(HYDROXYETHYL)ETHER, Jouberin
Authors:Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X.
Deposit date:2012-04-23
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors.
Proteomics, 12, 2012
4F16
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BU of 4f16 by Molmil
Crystal Structure of the alpha spectrin SH3 domain at pH 5
Descriptor: Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2012-05-06
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain at pH 5
To be Published
6XVO
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BU of 6xvo by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
4F17
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BU of 4f17 by Molmil
Crystal Structure of the alpha spectrin SH3 domain at pH 9
Descriptor: Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2012-05-06
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain at pH 9
To be Published
4FSS
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BU of 4fss by Molmil
Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2012-06-27
Release date:2012-07-18
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
To be published
6XVM
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BU of 6xvm by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Plaza-Garrido, M.
Deposit date:2020-01-22
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6ATV
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BU of 6atv by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, proline-rich motif in IAV-NS1
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-08-29
Release date:2018-08-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Molecular Mechanisms of Tight Binding through Fuzzy Interactions.
Biophys. J., 114, 2018
6XX3
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX4
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Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
3M0P
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BU of 3m0p by Molmil
Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 4.
Descriptor: SULFATE ION, Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2010-03-03
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures
Acta Crystallogr.,Sect.D, 2011
3M0S
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BU of 3m0s by Molmil
Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 7
Descriptor: SULFATE ION, Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2010-03-03
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures
Acta Crystallogr.,Sect.D, 2011
6XX5
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BU of 6xx5 by Molmil
Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XX2
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BU of 6xx2 by Molmil
Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Cu(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2020-01-26
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6C4S
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BU of 6c4s by Molmil
Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69
Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION
Authors:Kall, S.L, Lavie, A.
Deposit date:2018-01-12
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase.
Sci Rep, 9, 2019
3H0F
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BU of 3h0f by Molmil
Crystal structure of the human Fyn SH3 R96W mutant
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Proto-oncogene tyrosine-protein kinase Fyn
Authors:Ponchon, L, Hoh, F, Labesse, G, Dumas, C, Arold, S.T.
Deposit date:2009-04-09
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3H0I
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BU of 3h0i by Molmil
human Fyn SH3 domain R96I mutant, crystal form II
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn
Authors:Dumas, C, Strub, M.-P, Arold, S.T.
Deposit date:2009-04-09
Release date:2010-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3M0R
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BU of 3m0r by Molmil
Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 6.
Descriptor: SULFATE ION, Spectrin alpha chain, brain
Authors:Gavira, J.A, Camara-Artigas, A.
Deposit date:2010-03-03
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures
Acta Crystallogr.,Sect.D, 2011
3GBQ
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BU of 3gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
4EIK
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BU of 4eik by Molmil
Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12
Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide
Authors:Camara-Artigas, A.
Deposit date:2012-04-05
Release date:2013-04-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
3M0U
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BU of 3m0u by Molmil
Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Hexagonal crystal obtained in sodium formate at pH 6.5.
Descriptor: FORMIC ACID, Spectrin alpha chain, brain
Authors:Gavira, J.A, Camara-Artigas, A.
Deposit date:2010-03-03
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures
Acta Crystallogr.,Sect.D, 2011
3M0Q
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BU of 3m0q by Molmil
Crystal Structure of the R21D mutant of alpha-spectrin SH3 domain. Crystal obtained in ammonium sulphate at pH 5.
Descriptor: SULFATE ION, Spectrin alpha chain, brain
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2010-03-03
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Understanding the polymorphic behaviour of a mutant of the alpha-spectrin SH3 domain by means of two 1.1 A structures
Acta Crystallogr.,Sect.D, 2011
4GLM
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BU of 4glm by Molmil
Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens]
Descriptor: Dynamin-binding protein, UNKNOWN ATOM OR ION
Authors:Dong, A, Guan, X, Huang, H, Tempel, W, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2012-08-14
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens]
to be published
4GBQ
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BU of 4gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
3IQL
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BU of 3iql by Molmil
Crystal structure of the rat endophilin-A1 SH3 domain
Descriptor: CHLORIDE ION, Endophilin-A1
Authors:Trempe, J.F, Kozlov, G, Camacho, E.M, Gehring, K.
Deposit date:2009-08-20
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009

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