PDB: 591 件ウェブページステータス検索Chemie searchBIRD

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1SKJ	COCRYSTAL STRUCTURE OF UREA-SUBSTITUTED PHOSPHOPEPTIDE COMPLEX 分子名称: 4-[3-CARBOXYMETHYL-3-(4-PHOSPHONOOXY-BENZYL)-UREIDO]-4-[(3-CYCLOHEXYL-PROPYL)-METHYL-CARBAMOYL]BUTYRIC ACID, PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN 著者 Holland, D.R, Rubin, J.R. 登録日 1997-09-18 公開日 1998-02-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand. J.Med.Chem., 40, 1997
1A1A	C-SRC (SH2 DOMAIN WITH C188A MUTATION) COMPLEXED WITH ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) 分子名称: ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-10 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A08	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) 分子名称: ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-09 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A09	C-src (SH2 domain) complexed with ace-formyl phosphotyr-glu-(n,n-dipentyl amine) 分子名称: ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-10 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1E	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE) 分子名称: ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-10 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1C	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL)) 分子名称: ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL)), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-10 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1B	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) 分子名称: ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-10 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A07	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE) 分子名称: ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE 著者 Shewchuk, L, Jordan, S. 登録日 1997-12-09 公開日 1998-04-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
7WFY	Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide 分子名称: Amyloid beta A4 protein-binding family B member 1 (protein), Guanine nucleotide exchange factor VAV2 著者 Zhang, Y.J, Liu, Y.R, Wu, B. 登録日 2021-12-27 公開日 2022-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.449 Å) 主引用文献 Vav2 is a novel APP-interacting protein that regulates APP protein level. Sci Rep, 12, 2022
1AB2	THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL 分子名称: C-ABL TYROSINE KINASE SH2 DOMAIN 著者 Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. 登録日 1993-07-19 公開日 1994-01-31 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the src homology 2 domain of c-abl. Cell(Cambridge,Mass.), 70, 1992
7T1K	Crystal structure of a superbinder Fes SH2 domain (sFes1) in complex with a high affinity phosphopeptide 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MALONATE ION, ... 著者 Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. 登録日 2021-12-02 公開日 2022-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
7T1L	Crystal structure of a superbinder Fes SH2 domain (sFesS) in complex with a high affinity phosphopeptide 分子名称: CHLORIDE ION, SODIUM ION, Synthetic phosphotyrosine-containing Ezrin-derived peptide, ... 著者 Martyn, G.D, Singer, A.U, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. 登録日 2021-12-02 公開日 2022-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
7T1U	Crystal structure of a superbinder Src SH2 domain (sSrcF) in complex with a high affinity phosphopeptide 分子名称: Proto-oncogene tyrosine-protein kinase Src, Synthetic phosphopeptide, ZINC ION 著者 Martyn, G.D, Singer, A.U, Manczyk, N, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. 登録日 2021-12-02 公開日 2022-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
1AYB	CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE 分子名称: PEPTIDE IRS-1-895, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) 著者 Lee, C.-H, Kuriyan, J. 登録日 1994-05-15 公開日 1994-08-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure, 2, 1994
1AYD	CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE 分子名称: PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) 著者 Lee, C.-H, Kuriyan, J. 登録日 1994-05-15 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure, 2, 1994
1AOT	NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE 分子名称: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE 著者 Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D. 登録日 1997-07-10 公開日 1998-01-14 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure, 5, 1997
1TZE	SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2) 分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 著者 Rahuel, J, Grutter, M.G. 登録日 1996-06-06 公開日 1997-07-07 最終更新日 2011-11-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode. Nat.Struct.Biol., 3, 1996
5JN0	CRK-II SH2 domain 分子名称: CHLORIDE ION, CRK-II SH2 domain 著者 Cho, J.-H. 登録日 2016-04-29 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.677 Å) 主引用文献 CRK-II SH2 domain To Be Published
5KAZ	Human SH2D1B structure 分子名称: SH2 domain-containing protein 1B, SULFATE ION 著者 Taha, M, Nezerwa, E, Nam, H.-J. 登録日 2016-06-02 公開日 2017-04-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The X-ray Crystallographic Structure of Human EAT2 (SH2D1B). Protein Pept. Lett., 23, 2016
1WQU	Solution structure of the human FES SH2 domain 分子名称: Proto-oncogene tyrosine-protein kinase FES/FPS 著者 Scott, A, Pantoja-Uceda, D, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Tanaka, A, Sugano, S, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-10-02 公開日 2005-06-14 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes J.Biomol.NMR, 31, 2005
1X0N	NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor 分子名称: 4-[(10S,14S,18S)-18-(2-AMINO-2-OXOETHYL)-14-(1-NAPHTHYLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL]BENZYLPHOSPHONIC ACID, Growth factor receptor-bound protein 2 著者 Ogura, K, Shiga, T, Yuzawa, S, Yokochi, M, Burke, T.R, Inagaki, F. 登録日 2005-03-24 公開日 2005-04-19 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 NMR structure of growth factor receptor binding protein SH2 domain complexed with the inhibitor To be Published
1X6C	Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 分子名称: Tyrosine-protein phosphatase, non-receptor type 6 著者 Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-17 公開日 2005-11-17 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 To be Published
1BFI	SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, 30 STRUCTURES 分子名称: P85 ALPHA 著者 Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. 登録日 1997-11-18 公開日 1998-02-25 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
1AYC	CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE 分子名称: PEPTIDE PDGFR-740, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) 著者 Lee, C.-H, Kuriyan, J. 登録日 1994-05-15 公開日 1994-08-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure, 2, 1994
1BHF	P56LCK SH2 DOMAIN INHIBITOR COMPLEX 分子名称: INHIBITOR ACE-IPA-GLU-GLU-ILE, T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK 著者 Tong, L, Warren, T.C, Lukas, S, Schembri-King, J, Betageri, R, Proudfoot, J.R, Jakes, S. 登録日 1998-06-08 公開日 1998-10-21 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding. J.Biol.Chem., 273, 1998

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