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8U2C
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Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374)
Descriptor: 5D3 Fab heavy chain variable domain, 5D3 Fab light chain variable domain, Broad substrate specificity ATP-binding cassette transporter ABCG2, ...
Authors:Chen, M, Pintilie, G.
Deposit date:2023-09-05
Release date:2023-11-15
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models.
Nat.Methods, 21, 2024
7EHL
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BU of 7ehl by Molmil
Cryo-EM structure of human ABCB8 transporter in nucleotide binding state
Descriptor: CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ...
Authors:Li, S.J, Yang, X, Shen, Y.Q.
Deposit date:2021-03-29
Release date:2021-05-05
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY
Cite:Cryo-EM structure of human ABCB8 transporter in nucleotide binding state.
Biochem.Biophys.Res.Commun., 557, 2021
7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
8TZL
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BU of 8tzl by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, full-length
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
Authors:Hao, A, Lee, S.-Y.
Deposit date:2023-08-27
Release date:2023-12-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZJ
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BU of 8tzj by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
Authors:Hao, A, Lee, S.-Y.
Deposit date:2023-08-27
Release date:2023-12-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8TZK
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BU of 8tzk by Molmil
Cryo-EM structure of Vibrio cholerae FtsE/FtsX/EnvC complex, shortened
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ...
Authors:Hao, A, Lee, S.-Y.
Deposit date:2023-08-27
Release date:2023-12-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
8UFH
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BU of 8ufh by Molmil
Acinetobacter baylyi LptB2FG bound to Acinetobacter baylyi lipopolysaccharide and a macrocyclic peptide
Descriptor: (2~{R},4~{R},5~{R},6~{R})-2-[(2~{R},4~{R},5~{R},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4-[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-acetamido-6-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-5-oxidanyl-oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{S})-3-dodecanoyloxydodecanoyl]oxy-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-heptanoyloxynonanoyl]amino]-3-oxidanyl-4-[(3~{R})-3-oxidanyloctanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-5-[[(3~{S})-3-[(3~{R})-3-oxidanyldodecanoyl]oxydecanoyl]amino]-3-phosphonooxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, (7S,10S,13S,17P)-10-(4-aminobutyl)-7-(3-aminopropyl)-17-(6-aminopyridin-3-yl)-20-chloro-13-[(1H-indol-3-yl)methyl]-12-methyl-6,7,9,10,12,13,15,16-octahydropyrido[2,3-b][1,5,8,11,14]benzothiatetraazacycloheptadecine-8,11,14(5H)-trione, LPS export ABC transporter permease LptG, ...
Authors:Pahil, K.S, Gilman, M.S.A, Baidin, V, Kruse, A.C, Kahne, D.
Deposit date:2023-10-04
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
8UFG
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BU of 8ufg by Molmil
Acinetobacter baylyi LptB2FG bound to Acinetobacter baylyi lipopolysaccharide
Descriptor: (2~{R},4~{R},5~{R},6~{R})-2-[(2~{R},4~{R},5~{R},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4-[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-acetamido-6-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-5-oxidanyl-oxan-2-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{S})-3-dodecanoyloxydodecanoyl]oxy-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-heptanoyloxyundecanoyl]amino]-3-oxidanyl-4-[(3~{R})-3-oxidanyloctanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-5-[[(3~{S})-3-[(3~{R})-3-oxidanyldecanoyl]oxydecanoyl]amino]-3-phosphonooxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, DODECYL-BETA-D-MALTOSIDE, LPS export ABC transporter permease LptG, ...
Authors:Pahil, K.S, Gilman, M.S.A, Baidin, V, Kruse, A.C, Kahne, D.
Deposit date:2023-10-04
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A new antibiotic traps lipopolysaccharide in its intermembrane transporter.
Nature, 625, 2024
7D7N
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BU of 7d7n by Molmil
Cryo-EM structure of human ABCB6 transporter
Descriptor: ATP-binding cassette sub-family B member 6, mitochondrial
Authors:Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
Deposit date:2020-10-05
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
8QOE
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BU of 8qoe by Molmil
Inward-facing conformation of the ABC transporter BmrA
Descriptor: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
Authors:Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M.
Deposit date:2023-09-28
Release date:2023-12-20
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
7D7R
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BU of 7d7r by Molmil
Cryo-EM structure of the core domain of human ABCB6 transporter
Descriptor: ATP-binding cassette sub-family B member 6, mitochondrial
Authors:Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
Deposit date:2020-10-05
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7EFO
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BU of 7efo by Molmil
LptB2FG-LPS from Klebsiella pneumoniae in nanodiscs
Descriptor: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, LPS export ABC transporter permease LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
Authors:Luo, Q, Shi, H.
Deposit date:2021-03-22
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Cryo-EM structures of LptB 2 FG and LptB 2 FGC from Klebsiella pneumoniae in complex with lipopolysaccharide.
Biochem.Biophys.Res.Commun., 571, 2021
8SCB
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BU of 8scb by Molmil
Terminating ribosome with SRI-41315
Descriptor: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ...
Authors:Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S.
Deposit date:2023-04-05
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure and consequences of eRF1 glued to the ribosomal decoding center
To Be Published
8RQ3
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BU of 8rq3 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
Descriptor: ATP-binding cassette sub-family C member 2
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RQ4
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BU of 8rq4 by Molmil
Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid
Descriptor: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE
Authors:Mazza, T, Beis, K.
Deposit date:2024-01-17
Release date:2024-02-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
7E7Q
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BU of 7e7q by Molmil
Cryo-EM structure of human ABCA4 in ATP-bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xie, T, Zhang, Z.K, Gong, X.
Deposit date:2021-02-26
Release date:2021-06-30
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
7E7O
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BU of 7e7o by Molmil
Cryo-EM structure of human ABCA4 in NRPE-bound state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
Authors:Xie, T, Zhang, Z.K, Gong, X.
Deposit date:2021-02-26
Release date:2021-06-30
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
7E7I
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BU of 7e7i by Molmil
Cryo-EM structure of human ABCA4 in the apo state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
Authors:Xie, T, Zhang, Z.K, Gong, X.
Deposit date:2021-02-26
Release date:2021-06-30
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of substrate recognition and translocation by human ABCA4.
Nat Commun, 12, 2021
8UBR
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BU of 8ubr by Molmil
Complex of the phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with CFTRinh-172 and ATP/Mg
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 4-[(Z)-{(3M)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Young, P.G, Fiedorczuk, K, Chen, J.
Deposit date:2023-09-24
Release date:2024-02-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for CFTR inhibition by CFTR inh -172.
Proc.Natl.Acad.Sci.USA, 121, 2024
7DV5
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BU of 7dv5 by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-01-12
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
7F02
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BU of 7f02 by Molmil
Cytochrome c-type biogenesis protein CcmABCD from E. coli
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ...
Authors:Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P.
Deposit date:2021-06-03
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
8TSW
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BU of 8tsw by Molmil
S. thermodepolymerans KpsMT-KpsE Apo 1
Descriptor: ABC transporter ATP-binding protein, Capsular biosynthesis protein, Transport permease protein
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-12
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8TT3
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BU of 8tt3 by Molmil
S. thermodepolymerans KpsM-KpsE in Glycolipid 2 state with rigid body fitted KpsT
Descriptor: (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ...
Authors:Kuklewicz, J, Zimmer, J.
Deposit date:2023-08-12
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular insights into capsular polysaccharide secretion.
Nature, 628, 2024
8TI1
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BU of 8ti1 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024
8TI2
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BU of 8ti2 by Molmil
Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ...
Authors:Driggers, C.M, Shyng, S.-L.
Deposit date:2023-07-18
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
Nat Commun, 15, 2024

221051

PDB entries from 2024-06-12

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