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T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Chloro-6-Methyl-Aniline
Descriptor:	2-CHLORO-6-METHYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:	Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:	2003-03-26
Release date:	2004-04-06
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004

1OWY

T4 Lysozyme Cavity Mutant L99A/M102Q Bound With 2-Propyl-Aniline
Descriptor:	2-PROPYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:	Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:	2003-03-31
Release date:	2004-04-13
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004

1PQI

T4 LYSOZYME CORE REPACKING MUTANT I118L/CORE7/TA
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:	Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W.
Deposit date:	2003-06-18
Release date:	2003-10-07
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.57 Å)
Cite:	Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003

1L59

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L70

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Zhang, X, Matthews, B.W.
Deposit date:	1991-09-23
Release date:	1991-10-15
Last modified:	2017-11-29
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L75

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Zhang, X, Matthews, B.W.
Deposit date:	1991-09-23
Release date:	1991-10-15
Last modified:	2020-07-22
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1LI2

T4 Lysozyme Mutant L99A/M102Q Bound by Phenol
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:	Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K.
Deposit date:	2002-04-17
Release date:	2002-05-08
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002

1PQO

T4 Lysozyme Core Repacking Mutant L118I/TA
Descriptor:	2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme, ...
Authors:	Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W.
Deposit date:	2003-06-18
Release date:	2003-10-07
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003

1PQD

T4 LYSOZYME CORE REPACKING MUTANT CORE10/TA
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ...
Authors:	Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W.
Deposit date:	2003-06-18
Release date:	2003-10-07
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003

1PQK

Repacking of the Core of T4 Lysozyme by Automated Design
Descriptor:	Lysozyme
Authors:	Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W.
Deposit date:	2003-06-18
Release date:	2003-10-07
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003

6FW2

Crystal Structure of human mARC1
Descriptor:	2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MOLYBDATE ION, Mitochondrial amidoxime-reducing component 1,Endolysin,Mitochondrial amidoxime-reducing component 1, ...
Authors:	Kubitza, C, Scheidig, A.
Deposit date:	2018-03-05
Release date:	2018-10-31
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.78 Å)
Cite:	Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

7P41

Crystal Structure of human mARC1 A165T Variant
Descriptor:	2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Mitochondrial amidoxime-reducing component 1,Endolysin,Mitochondrial amidoxime-reducing component 1, ...
Authors:	Struwe, M.A, Scheidig, A.J.
Deposit date:	2021-07-09
Release date:	2021-08-18
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein. Hepatol Commun, 6, 2022

4ARJ

Crystal structure of a pesticin (translocation and receptor binding domain) from Y. pestis and T4-lysozyme chimera
Descriptor:	PESTICIN, LYSOZYME, SULFATE ION
Authors:	Zeth, K, Patzer, S.I, Albrecht, R, Braun, V.
Deposit date:	2012-04-24
Release date:	2012-05-09
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (2.593 Å)
Cite:	Structure and Mechanistic Studies of Pesticin, a Bacterial Homolog of Phage Lysozymes. J.Biol.Chem., 287, 2012

2Z6B

Crystal Structure Analysis of (gp27-gp5)3 conjugated with Fe(III) protoporphyrin
Descriptor:	1-ETHYL-PYRROLIDINE-2,5-DIONE, Baseplate structural protein Gp27, Tail-associated lysozyme
Authors:	Koshiyama, T, Yokoi, N, Ueno, T, Kanamaru, S, Nagano, S, Shiro, Y, Arisaka, F, Watanabe, Y.
Deposit date:	2007-07-28
Release date:	2008-04-15
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Molecular design of heteroprotein assemblies providing a bionanocup as a chemical reactor. Small, 4, 2008

5IV5

Cryo-electron microscopy structure of the hexagonal pre-attachment T4 baseplate-tail tube complex
Descriptor:	Baseplate hub protein gp27, Baseplate tail-tube protein gp48, Baseplate tail-tube protein gp54, ...
Authors:	Taylor, N.M.I, Guerrero-Ferreira, R.C, Goldie, K.N, Stahlberg, H, Leiman, P.G.
Deposit date:	2016-03-19
Release date:	2016-05-18
Last modified:	2018-02-07
Method:	ELECTRON MICROSCOPY (4.11 Å)
Cite:	Structure of the T4 baseplate and its function in triggering sheath contraction. Nature, 533, 2016

6P5V

Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide
Authors:	Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A.
Deposit date:	2019-05-31
Release date:	2019-09-11
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.398 Å)
Cite:	Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019

1WTH

Crystal structure of gp5-S351L mutant and gp27 complex
Descriptor:	Baseplate structural protein Gp27, PHOSPHATE ION, POTASSIUM ION, ...
Authors:	Kanamaru, S, Ishiwata, Y, Suzuki, T, Rossmann, M.G, Arisaka, F.
Deposit date:	2004-11-23
Release date:	2005-03-08
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Control of bacteriophage t4 tail lysozyme activity during the infection process J.Mol.Biol., 346, 2005

6P5W

Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Descriptor:	3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera
Authors:	Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A.
Deposit date:	2019-05-31
Release date:	2019-09-11
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.69 Å)
Cite:	Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019

6D9M

T4-Lysozyme fusion to Geobacter GGDEF
Descriptor:	ACETATE ION, Fusion protein of Endolysin,Response receiver sensor diguanylate cyclase, GAF domain-containing, ...
Authors:	Hallberg, Z, Doxzen, K, Kranzusch, P.J, Hammond, M.
Deposit date:	2018-04-30
Release date:	2019-04-10
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration. Elife, 8, 2019

4N9N

Crystal Structure of Saccharomyces cerevisiae Upc2 Transcription Factor fused with T4 Lysozyme
Descriptor:	Sterol uptake control protein 2, Lysozyme
Authors:	Yang, H, Im, Y.J.
Deposit date:	2013-10-21
Release date:	2014-12-03
Last modified:	2017-08-16
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Structural mechanism of ergosterol regulation by fungal sterol nuclear receptor Upc2 To be Published

4UIS

The cryoEM structure of human gamma-Secretase complex
Descriptor:	GAMMA-SECRETASE, LYSOZYME
Authors:	Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:	2015-04-03
Release date:	2015-06-10
Last modified:	2017-08-02
Method:	ELECTRON MICROSCOPY (4.4 Å)
Cite:	Structural Basis of Human Gamma-Secretase Assembly. Proc.Natl.Acad.Sci.USA, 112, 2015

4W8F

Crystal structure of the dynein motor domain in the AMPPNP-bound state
Descriptor:	Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:	Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D.
Deposit date:	2014-08-24
Release date:	2014-11-12
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (3.541 Å)
Cite:	Allosteric communication in the Dynein motor domain. Cell, 159, 2014

7XB5

Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme
Descriptor:	fusion protein of Sterol uptake control protein 2 and Endolysin
Authors:	Tan, L, Im, Y.J.
Deposit date:	2022-03-20
Release date:	2022-09-07
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3.44 Å)
Cite:	Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022

4YX7

Complex of SpaO(SPOA1,2) and OrgB(APAR)::T4lysozyme fusion protein
Descriptor:	Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO
Authors:	Notti, R.Q, Stebbins, C.E.
Deposit date:	2015-03-22
Release date:	2015-06-03
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.0007 Å)
Cite:	A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015

4YXC

Complex of FliM(SPOA)::FliN fusion protein and FliH(APAR)::T4lysozyme fusion protein
Descriptor:	Flagellar assembly protein H,Endolysin, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN
Authors:	Notti, R.Q, Stebbins, C.E.
Deposit date:	2015-03-23
Release date:	2015-06-03
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015

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Total results:	868
Displayed results:	25
Sorted by:	Hit score (from highest)
Query:	PF00959