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5NDV
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BU of 5ndv by Molmil
Crystal structure of Paromomycin bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NZS
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BU of 5nzs by Molmil
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
Descriptor: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZR
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BU of 5nzr by Molmil
The structure of the COPI coat leaf
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
6XIR
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BU of 6xir by Molmil
Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress
Descriptor: 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Zhou, Y, Bartesaghi, A, Silva, G.M.
Deposit date:2020-06-21
Release date:2020-08-26
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XTY
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BU of 6xty by Molmil
CryoEM structure of human CMG bound to AND-1 (CMGA)
Descriptor: Cell division control protein 45 homolog, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ...
Authors:Rzechorzek, N.J, Pellegrini, L, Chirgadze, D.Y, Hardwick, S.W.
Deposit date:2020-01-16
Release date:2020-05-27
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (6.77 Å)
Cite:CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
Nucleic Acids Res., 48, 2020
1EN2
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BU of 1en2 by Molmil
UDA TETRASACCHARIDE COMPLEX. CRYSTAL STRUCTURE OF URTICA DIOICA AGGLUTININ, A SUPERANTIGEN PRESENTED BY MHC MOLECULES OF CLASS I AND CLASS II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AGGLUTININ ISOLECTIN I/AGGLUTININ ISOLECTIN V/ AGGLUTININ ISOLECTIN VI
Authors:Saul, F.A, Rovira, P, Boulot, G, Van Damme, E.J.M, Peumans, W.J, Truffa-Bachi, P, Bentley, G.A.
Deposit date:2000-03-20
Release date:2000-06-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of Urtica dioica agglutinin, a superantigen presented by MHC molecules of class I and class II.
Structure Fold.Des., 8, 2000
6XAJ
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BU of 6xaj by Molmil
Crystal structure of NzeB
Descriptor: 1,2-ETHANEDIOL, NzeB, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shende, V.V, Khatri, Y, Newmister, S.A, Sanders, J.N, Lindovska, P, Yu, F, Doyon, T.J, Kim, J, Movassaghi, M, Houk, K.N, Sherman, D.H.
Deposit date:2020-06-04
Release date:2021-06-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase.
J.Am.Chem.Soc., 142, 2020
4KFM
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BU of 4kfm by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with the beta-gamma G protein subunits
Descriptor: DODECYL-BETA-D-MALTOSIDE, G protein-activated inward rectifier potassium channel 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Whorton, M.R, MacKinnon, R.
Deposit date:2013-04-27
Release date:2013-06-12
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:X-ray structure of the mammalian GIRK2-beta gamma G-protein complex.
Nature, 498, 2013
6XU6
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BU of 6xu6 by Molmil
Drosophila melanogaster Testis 80S ribosome
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
Authors:Hopes, T, Agapiou, M, Norris, K, McCarthy, C.G.P, OConnell, M.J, Fontana, J, Aspden, J.L.
Deposit date:2020-01-17
Release date:2021-07-28
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Nucleic Acids Res., 50, 2022
6YBT
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BU of 6ybt by Molmil
Structure of a human 48S translational initiation complex - eIF3bgi
Descriptor: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit I
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.0305 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
6YLF
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BU of 6ylf by Molmil
Rix1-Rea1 pre-60S particle - Rea1, body 3 (rigid body refinement, composite structure of Rea1 ring and tail)
Descriptor: Midasin, Ribosome assembly protein 4
Authors:Kater, L, Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
6YBS
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BU of 6ybs by Molmil
Structure of a human 48S translational initiation complex - head
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6Y7O
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BU of 6y7o by Molmil
The complex between the eight-bladed symmetrical designer protein Tako8 and the silicotungstic acid Keggin (STA)
Descriptor: Keggin (STA), Tako8
Authors:Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D.
Deposit date:2020-03-02
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters
Cryst.Growth Des., 2021
4M70
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BU of 4m70 by Molmil
Crystal structure of potato Rx-CC domain in complex with RanGAP2-WPP domain
Descriptor: Ran GTPase activating protein 2, Rx protein
Authors:Chai, J, Hao, W.
Deposit date:2013-08-12
Release date:2013-11-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural Basis for the Interaction between the Potato Virus X Resistance Protein (Rx) and Its Cofactor Ran GTPase-activating Protein 2 (RanGAP2)
J.Biol.Chem., 288, 2013
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6Y2L
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BU of 6y2l by Molmil
Structure of human ribosome in POST state
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
Deposit date:2020-02-16
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
6YLG
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BU of 6ylg by Molmil
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kater, L, Beckmann, R.
Deposit date:2020-04-07
Release date:2020-07-29
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
4LG8
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BU of 4lg8 by Molmil
Crystal structure of PRPF19 WD40 repeats
Descriptor: Pre-mRNA-processing factor 19, SODIUM ION, UNKNOWN ATOM OR ION
Authors:Xu, C, Tempel, W, He, H, Dobrovetsky, E, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-06-27
Release date:2013-08-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of the WD40 domain of human PRPF19.
Biochem. Biophys. Res. Commun., 493, 2017
4LG9
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BU of 4lg9 by Molmil
Crystal structure of TBL1XR1 WD40 repeats
Descriptor: F-box-like/WD repeat-containing protein TBL1XR1, UNKNOWN ATOM OR ION
Authors:Xu, C, Tempel, W, He, H, Wu, X, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-06-27
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of TBL1XR1 WD40 repeats
TO BE PUBLISHED
6Z6N
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BU of 6z6n by Molmil
Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6J
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BU of 6z6j by Molmil
Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6ZJ3
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BU of 6zj3 by Molmil
Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis
Descriptor: 18S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Matzov, D, Halfon, H, Zimmerman, E, Rozenberg, H, Bashan, A, Gray, M.W, Yonath, A.E, Shalev-Benami, M.
Deposit date:2020-06-27
Release date:2020-10-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis.
Nucleic Acids Res., 48, 2020
6Z6K
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BU of 6z6k by Molmil
Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
4MK0
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BU of 4mk0 by Molmil
Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed paroxetine derivative
Descriptor: 5-{[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1H-isoindol-1-one, Beta-adrenergic receptor kinase 1, GLYCEROL, ...
Authors:Homan, K.T, Tesmer, J.J.G.
Deposit date:2013-09-04
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog.
Mol.Pharmacol., 85, 2014

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