PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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7G8S	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1270393711 Descriptor: 5-(methoxymethyl)-1,2-oxazole-3-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G94	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1575337975 Descriptor: (2P)-5-fluoro-2-(1H-pyrazol-5-yl)pyridine, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.47 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G89	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1192341021 Descriptor: 1-(5-amino-2H-isoindol-2-yl)ethan-1-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.901 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8C	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1037511924 Descriptor: 1-(difluoromethyl)-1H-indol-5-amine, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.176 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G97	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z57899718 Descriptor: 2-AMINOMETHYL-PYRIDINE, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G98	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z4605084898 Descriptor: 1,3-dimethylimidazolidine, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.878 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8D	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z104474228 Descriptor: 3-methylthiophene-2-carboxylic acid, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.937 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8R	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1270087714 Descriptor: (2R,6S)-2,6-dimethyl-4-(3-methyl-1,2,4-thiadiazol-5-yl)morpholine, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.44 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G9B	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102116-001 Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-(3-methylphenyl)acetamide, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Method: X-RAY DIFFRACTION (2.553 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G9I	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102253-001 Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-[(2-methylphenyl)methyl]acetamide, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.202 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G91	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1509257513 Descriptor: (4S)-N,2-dimethyl-4,5,6,7-tetrahydro-1,3-benzothiazole-4-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.292 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G9A	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102113-001 Descriptor: 3-acetamido-N-methylbenzamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Method: X-RAY DIFFRACTION (2.583 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G9J	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with PCM-0102281-001 Descriptor: 1-(3,4-dihydropyrazin-1(2H)-yl)ethan-1-one, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.97 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G85	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z111529496 Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, Rho guanine nucleotide exchange factor 2, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.735 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8F	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1079168976 Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, Rho guanine nucleotide exchange factor 2, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.42 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8A	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z100642432 Descriptor: 2-bromo-4-fluoro-N,N-dimethylbenzamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
7G8X	ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1416571195 Descriptor: 2-(cyclopentylamino)pyridine-4-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... Authors: Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E. Deposit date: 2023-06-22 Release date: 2023-07-12 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.711 Å) Cite: ARHGEF2 PanDDA analysis group deposition To Be Published
2VT5	FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE -1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH A DUAL BINDING AMP SITE INHIBITOR Descriptor: 4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE, FRUCTOSE-1,6-BISPHOSPHATASE 1 Authors: Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T. Deposit date: 2008-05-09 Release date: 2008-07-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Allosteric Fbpase Inhibitors Gain 10(5) Times in Potency When Simultaneously Binding Two Neighboring AMP Sites. Bioorg.Med.Chem.Lett., 18, 2008
2VUT	Crystal structure of NAD-bound NmrA-AreA zinc finger complex Descriptor: CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. Deposit date: 2008-05-30 Release date: 2008-07-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
7Q16	Human 14-3-3 zeta fused to the BAD peptide including phosphoserine-74 Descriptor: 14-3-3 protein zeta/delta,Bcl2-associated agonist of cell death Authors: Sluchanko, N.N, Tugaeva, K.V, Gushchin, I, Remeeva, A, Kovalev, K, Cooley, R.B. Deposit date: 2021-10-18 Release date: 2021-11-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.356 Å) Cite: Crystal structure of human 14-3-3 zeta complexed with the noncanonical phosphopeptide from proapoptotic BAD. Biochem.Biophys.Res.Commun., 583, 2021
2W9F	Crystal Structure of CDK4 in complex with a D-type cyclin Descriptor: CELL DIVISION PROTEIN KINASE 4, G1/S-SPECIFIC CYCLIN-D1 Authors: Day, P.J, Cleasby, A, Tickle, I.J, Reilly, M.O, Coyle, J.E, Holding, F.P, McMenamin, R.L, Yon, J, Chopra, R, Lengauer, C, Jhoti, H. Deposit date: 2009-01-23 Release date: 2009-03-10 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Crystal Structure of Human Cdk4 in Complex with a D-Type Cyclin. Proc.Natl.Acad.Sci.USA, 106, 2009
2VUU	Crystal structure of NADP-bound NmrA-AreA zinc finger complex Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, NITROGEN REGULATORY PROTEIN AREA, ... Authors: Kotaka, M, Johnson, C, Lamb, H.K, Hawkins, A.R, Ren, J, Stammers, D.K. Deposit date: 2008-05-30 Release date: 2008-07-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area. J.Mol.Biol., 381, 2008
2ERE	Crystal Structure of a Leu3 DNA-binding domain complexed with a 15mer DNA duplex Descriptor: 5'-D(*TP*TP*GP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*CP*A)-3', Regulatory protein LEU3, ZINC ION Authors: Fitzgerald, M.X, Marmorstein, R. Deposit date: 2005-10-24 Release date: 2006-04-04 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure, 14, 2006
2ER8	Crystal Structure of Leu3 DNA-binding domain complexed with a 12mer DNA duplex Descriptor: 5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*CP*GP*GP*G)-3', Regulatory protein LEU3, ZINC ION Authors: Fitzgerald, M.X, Marmorstein, R. Deposit date: 2005-10-24 Release date: 2006-04-04 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein. Structure, 14, 2006
3T06	Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA Authors: Bielnicki, J.A, Derewenda, U, Derewenda, Z.S. Deposit date: 2011-07-19 Release date: 2011-08-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF. J.Biol.Chem., 286, 2011

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