8CRR
| Local refinement of Band 3-III transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8CRT
| Local refinement of Rh trimer, glycophorin B and Band3-III transmembrane region, class 1a of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Band 3 anion transport protein, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8GV9
| The cryo-EM structure of hAE2 with chloride ion | Descriptor: | Anion exchange protein 2, CHLORIDE ION | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-14 | Release date: | 2023-04-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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7TYA
| Cryo-EM structure of human Anion Exchanger 1 modified with Diethyl Pyrocarbonate (DEPC) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, ... | Authors: | Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | Deposit date: | 2022-02-11 | Release date: | 2023-08-16 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Substrate binding and inhibition of the anion exchanger 1 transporter. Nat.Struct.Mol.Biol., 30, 2023
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8GV8
| The cryo-EM structure of hAE2 with DIDS | Descriptor: | 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2 | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-14 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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8GVF
| The outward-facing structure of hAE2 in basic pH | Descriptor: | Anion exchange protein 2 | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-15 | Release date: | 2023-04-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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8T44
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8T47
| Cryo-EM Analysis of AE1 Structure in 100 mM NaHCO3 Buffer: Form3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CARBONATE ION, ... | Authors: | Su, C.C. | Deposit date: | 2023-06-08 | Release date: | 2024-05-22 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Cryo-EM structure of the band 3 anion transport protein To Be Published
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8GVE
| The asymmetry structure of hAE2 | Descriptor: | Anion exchange protein 2 | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-15 | Release date: | 2023-04-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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7TY8
| Cryo-EM structure of human Anion Exchanger 1 bound to Niflumic Acid | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, ... | Authors: | Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | Deposit date: | 2022-02-11 | Release date: | 2023-08-16 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Substrate binding and inhibition of the anion exchanger 1 transporter. Nat.Struct.Mol.Biol., 30, 2023
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8JNI
| Structure of AE2 in complex with PIP2 | Descriptor: | Anion exchange protein 2, CHLORIDE ION, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | Authors: | Yin, Y.X, Ding, D. | Deposit date: | 2023-06-06 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional insights into the lipid regulation of human anion exchanger 2. Nat Commun, 15, 2024
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8CRQ
| Local refinement of Band 3-I transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8GVA
| The intermediate structure of hAE2 in basic pH | Descriptor: | Anion exchange protein 2 | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-14 | Release date: | 2023-04-12 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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7V19
| Local refinement of Band 3-II transmembrane domains, class 1 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-11 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8JNJ
| Structure of R932A/K1147A/H1148A mutant AE2 | Descriptor: | Anion exchange protein 2 | Authors: | Yin, Y.X, Ding, D. | Deposit date: | 2023-06-06 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional insights into the lipid regulation of human anion exchanger 2. Nat Commun, 15, 2024
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8CT3
| Local refinement of band3-I transmembrane region from class 2 of erythrocyte ankyrin-1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | Deposit date: | 2022-05-13 | Release date: | 2022-07-20 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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8GVH
| Human AE2 in acidic KNO3 | Descriptor: | Anion exchange protein 2, CHOLESTEROL HEMISUCCINATE | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | Deposit date: | 2022-09-15 | Release date: | 2023-04-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2. Nat Commun, 14, 2023
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7TY7
| Cryo-EM structure of human Anion Exchanger 1 bound to Bicarbonate | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ... | Authors: | Capper, M.J, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | Deposit date: | 2022-02-11 | Release date: | 2023-08-16 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Substrate binding and inhibition of the anion exchanger 1 transporter. Nat.Struct.Mol.Biol., 30, 2023
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4YZF
| Crystal structure of the anion exchanger domain of human erythrocyte Band 3 | Descriptor: | 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Band 3 anion transport protein, FAB fragment of Immunoglobulin (IgG) molecule | Authors: | Alguel, Y, Arakawa, T, Yugiri, T.K, Iwanari, H, Hatae, H, Iwata, M, Abe, Y, Hino, T, Suno, C.I, Kuma, H, Kang, D, Murata, T, Hamakubo, T, Cameron, A.D, Kobayashi, T, Hamasaki, N, Iwata, S. | Deposit date: | 2015-03-25 | Release date: | 2015-11-04 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of the anion exchanger domain of human erythrocyte band 3. Science, 350, 2015
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7TVZ
| Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ... | Authors: | Xia, X, Liu, S.H, Zhou, Z.H. | Deposit date: | 2022-02-06 | Release date: | 2022-06-08 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane. Nat.Struct.Mol.Biol., 29, 2022
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6CAA
| CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1 | Descriptor: | Electrogenic sodium bicarbonate cotransporter 1 | Authors: | Huynh, K.W, Jiang, J, Abuladze, N, Tsirulnikov, K, Kao, L, Shao, X, Newman, D, Azimov, R, Pushkin, A, Zhou, Z.H, Kurtz, I. | Deposit date: | 2018-01-29 | Release date: | 2018-03-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun, 9, 2018
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8D9N
| CryoEM structures of bAE1 captured in multiple states. | Descriptor: | Anion exchange protein | Authors: | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | Deposit date: | 2022-06-10 | Release date: | 2023-01-25 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations. Commun Biol, 5, 2022
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7TW3
| Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell | Descriptor: | Ankyrin-1, Band 3 anion transport protein, Protein 4.2 | Authors: | Xia, X, Liu, S.H, Zhou, Z.H. | Deposit date: | 2022-02-06 | Release date: | 2022-06-08 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane. Nat.Struct.Mol.Biol., 29, 2022
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7TW1
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7TW0
| Cryo-EM structure of human band 3-protein 4.2 complex in vertical conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, Protein 4.2 | Authors: | Xia, X, Liu, S.H, Zhou, Z.H. | Deposit date: | 2022-02-06 | Release date: | 2022-06-08 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane. Nat.Struct.Mol.Biol., 29, 2022
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