PDB: 66 件ウェブページステータス検索Chemie searchBIRD

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1F1H	CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Gill, H.S, Eisenberg, D. 登録日 2000-05-19 公開日 2001-04-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition. Biochemistry, 40, 2001
1F52	CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE SYNTHETASE, ... 著者 Gill, H.S, Pfluegl, G.M.U, Eisenberg, D. 登録日 2000-06-12 公開日 2000-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition. Biochemistry, 40, 2001
3ZXR	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1H-imidazol-4-yl)quinoline) and L-methionine-S- sulfoximine phosphate. 分子名称: 3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-08-15 公開日 2012-04-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors. J.Med.Chem., 55, 2012
2WHI	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor and L-methionine-S- sulfoximine phosphate. 分子名称: 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2009-05-05 公開日 2009-09-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
3ZXV	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridin-2-amine) and L- methionine-S-sulfoximine phosphate 分子名称: 4-(2-TERT-BUTYL-4-(6-METHOXYNAPHTHALEN-2-YL)-3H-IMIDAZOL-4-YL)PYRIDIN-2-AMINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-08-16 公開日 2012-04-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors. J.Med.Chem., 55, 2012
4ACF	CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH IMIDAZOPYRIDINE INHIBITOR ((4-(6-BROMO-3-(BUTYLAMINO)IMIDAZO(1,2-A)PYRIDIN-2-YL)PHENOXY) ACETIC ACID) AND L-METHIONINE-S-SULFOXIMINE PHOSPHATE. 分子名称: CHLORIDE ION, GLUTAMINE SYNTHETASE 1, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-12-15 公開日 2012-10-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis, Biological Evaluation and X-Ray Crystallographic Studies of Imidazo(1,2-A)Pyridine-Based Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors Medchemcomm, 3, 2012
2BVC	Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2005-06-23 公開日 2005-07-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights. Proc.Natl.Acad.Sci.USA, 102, 2005
2D3B	Crystal Structure of the Maize Glutamine Synthetase complexed with AMPPNP and Methionine sulfoximine 分子名称: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. 登録日 2005-09-26 公開日 2006-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
2D3A	Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Methionine sulfoximine Phosphate 分子名称: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MANGANESE (II) ION, ... 著者 Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. 登録日 2005-09-26 公開日 2006-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
2D3C	Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Phosphinothricin Phosphate 分子名称: (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. 登録日 2005-09-26 公開日 2006-07-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.81 Å) 主引用文献 Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
4LNK	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-glutamate-AMPPCP complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Glutamine synthetase, ... 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
4LNF	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q 分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.949 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
4LNN	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS 分子名称: Glutamine synthetase, MAGNESIUM ION, SULFATE ION 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
4LNI	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5793 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
4LNO	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: form two of GS-1 分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
7W85	Structural of the filamentous Escherichia coli glutamine synthetase 分子名称: Glutamine synthetase, NICKEL (II) ION 著者 Huang, P.-C, Chen, S.-K, Wu, K.-P. 登録日 2021-12-07 公開日 2022-04-06 最終更新日 2022-06-15 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis for the helical filament formation of Escherichia coli glutamine synthetase. Protein Sci., 31, 2022
7U5N	Cryo-EM Structure of Glutamine Synthetase 分子名称: Glutamine synthetase, MANGANESE (II) ION 著者 Morgan, C.E, Yu, E.W, Zhang, Z. 登録日 2022-03-02 公開日 2022-12-14 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
7V4L	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4J	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4I	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4K	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
8PVG	Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV 分子名称: Glutamine synthetase 著者 McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. 登録日 2023-07-17 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
8OOX	Glutamine synthetase from Methermicoccus shengliensis at a resolution of 3.09 A 分子名称: CITRIC ACID, GLYCEROL, Glutamine synthetase, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8OOW	Glutamine synthetase from Methermicoccus shengliensis at a resolution of 2.64 A 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Glutamine synthetase, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8OOZ	Glutamine synthetase from Methermicoccus shengliensis in complex with MgATP at 2.7 A resolution 分子名称: ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, GLYCEROL, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024

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