7CF9
 
 | | Structure of RyR1 (Ca2+/CHL) | | Descriptor: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | | Authors: | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | | Deposit date: | 2020-06-24 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
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7M6L
 | | High resolution structure of the membrane embedded skeletal muscle ryanodine receptor | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | | Authors: | Melville, Z, Kim, K, Clarke, O.B, Marks, A.R. | | Deposit date: | 2021-03-25 | | Release date: | 2021-08-18 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022
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7M6A
 | | High resolution structure of the membrane embedded skeletal muscle ryanodine receptor | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | | Authors: | Melville, Z, Kim, K, Clarke, O.B, Marks, A.R. | | Deposit date: | 2021-03-25 | | Release date: | 2021-09-08 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022
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6WOV
 | | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M. | | Deposit date: | 2020-04-25 | | Release date: | 2020-08-05 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (5.1 Å) | | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
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6WOU
 | | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | | Authors: | Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. | | Deposit date: | 2020-04-25 | | Release date: | 2020-08-05 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
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4UWA
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4UWE
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6FG3
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6FOO
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8VJK
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8VJJ
 | | Structure of mouse RyR1 (EGTA-only dataset) | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... | | Authors: | Weninger, G, Marks, A.R. | | Deposit date: | 2024-01-07 | | Release date: | 2024-01-17 | | Method: | ELECTRON MICROSCOPY (2.53 Å) | | Cite: | Structural insights into the regulation of RyR1 by S100A1.
To Be Published
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8VK4
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8DTZ
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8DTY
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8DVV
 | | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions | | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | | Authors: | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | | Deposit date: | 2022-07-29 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
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6MM7
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6MM6
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6MM8
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8DUJ
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8DRP
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8DTB
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5GL0
 | | Structure of RyR1 in a closed state (C4 conformer) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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8DVE
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5GKZ
 | | Structure of RyR1 in a closed state (C3 conformer) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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6M2W
 | | Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) | | Descriptor: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... | | Authors: | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | | Deposit date: | 2020-03-01 | | Release date: | 2020-09-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
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