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8HU2
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BU of 8hu2 by Molmil
Rattus Syntenin-1 PDZ domain with inhibitor
Descriptor: (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1
Authors:Heo, Y, Lee, J, Yun, J.H, Lee, W.
Deposit date:2022-12-22
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution.
To Be Published
4E35
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BU of 4e35 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
7NTK
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BU of 7ntk by Molmil
PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ...
Authors:Javorsky, A, Kvansakul, M.
Deposit date:2021-03-10
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
7NTJ
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PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex
Descriptor: Envelope small membrane protein, MAGUK p55 subfamily member 5
Authors:Javorsky, A, Kvansakul, M.
Deposit date:2021-03-10
Release date:2021-06-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
4E34
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BU of 4e34 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ...
Authors:Amacher, J.F, Beck, T, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
4E3B
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BU of 4e3b by Molmil
Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: Tax1-binding protein 3, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
5TYT
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BU of 5tyt by Molmil
Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
Descriptor: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera
Authors:Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z.
Deposit date:2016-11-21
Release date:2017-02-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.
Biochem. Biophys. Res. Commun., 485, 2017
1BFE
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BU of 1bfe by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
Descriptor: PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1B8Q
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SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE
Descriptor: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE)
Authors:Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M.
Deposit date:1999-02-01
Release date:1999-04-29
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
Nat.Struct.Biol., 6, 1999
5V6B
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BU of 5v6b by Molmil
Crystal structure of GIPC1
Descriptor: PDZ domain-containing protein GIPC1
Authors:Shang, G, Zhang, X.
Deposit date:2017-03-16
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.
Elife, 6, 2017
4Z33
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BU of 4z33 by Molmil
Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
Descriptor: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
Authors:Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P.
Deposit date:2015-03-30
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
4Z8J
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BU of 4z8j by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif
Descriptor: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27
Authors:Clairfeuille, T, Pavlos, N, Collins, B.M.
Deposit date:2015-04-09
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Role of SNX27-retromer in PTHR trafficking
To Be Published
5A2P
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BU of 5a2p by Molmil
THE COMPLEX STRUCTURE OF PDZ DOMAINS IN SYNTENIN-1 WITH 4L PEPTIDE
Descriptor: SYNDECAN-4, SYNTENIN-1
Authors:Yoo, J.H, Yun, J.H, Cho, H.S, Lee, W.
Deposit date:2015-05-21
Release date:2016-06-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Titl the Complex Structure of Pdz Domains in Syntenin-1 with 4L Peptide
To be Published
5D13
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BU of 5d13 by Molmil
Third PDZ domain (PDZ3) of PSD-95 complexed with CFMOC-KKETEV peptide
Descriptor: CFMOC-KKETEV peptide, Disks large homolog 4
Authors:De, S, Spaller, M.R, Olson, R.
Deposit date:2015-08-03
Release date:2016-08-17
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Chemically-modified peptides as inhibitors of PDZ3 of PSD-95
to be published
6QJI
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BU of 6qji by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3112
Descriptor: Disks large homolog 4, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2019-01-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJG
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BU of 6qjg by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 2
Descriptor: Disks large homolog 4
Authors:Camara-Artigas, A.
Deposit date:2019-01-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJK
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BU of 6qjk by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P43
Descriptor: Disks large homolog 4, GLYCEROL, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2019-01-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.046 Å)
Cite:Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJF
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BU of 6qjf by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 1
Descriptor: Disks large homolog 4
Authors:Camara-Artigas, A.
Deposit date:2019-01-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJL
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BU of 6qjl by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P21
Descriptor: Disks large homolog 4, GLYCEROL, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2019-01-24
Release date:2019-04-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.043 Å)
Cite:Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
7VZE
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BU of 7vze by Molmil
Crystal structure of PTPN4 PDZ bound to the PBM of HPV16 E6
Descriptor: Tyrosine-protein phosphatase non-receptor type 4, the PDZ-binding motif of HPV16 E6
Authors:Lee, H.S, Yun, H.-Y, Ku, B.
Deposit date:2021-11-16
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.882 Å)
Cite:Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
J.Microbiol, 60, 2022
7WEG
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BU of 7weg by Molmil
Complex structure of PDZD7 and FCHSD2
Descriptor: FCHSD2, PDZ domain-containing protein 7, ZINC ION
Authors:Wang, H, Lin, L, Lu, Q.
Deposit date:2021-12-23
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2.
Biochem.J., 479, 2022
8WWR
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BU of 8wwr by Molmil
Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Omble, A, Mahajan, S, Kulkarni, K.A.
Deposit date:2023-10-26
Release date:2024-05-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
7X2E
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BU of 7x2e by Molmil
Structure of USH1C PDZ2 and coiled-coil in complex with CDHR2 C-terminal tail
Descriptor: Cadherin-related family member 2, GLYCEROL, Harmonin
Authors:Yan, W, Chen, G, Li, J.
Deposit date:2022-02-25
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the Harmonin PDZ2 and coiled-coil domains in a complex with CDHR2 tail and its implications.
Faseb J., 36, 2022
5MZ7
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BU of 5mz7 by Molmil
Crystal Structure of the third PDZ domain from the synaptic protein PSD-95 with incorporated Azidohomoalanine
Descriptor: Disks large homolog 4
Authors:Kudlinzki, D, Lehner, F, Witt, K, Linhard, V.L, Silvers, R, Schwalbe, H.
Deposit date:2017-01-31
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding.
Chembiochem, 18, 2017
7W71
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BU of 7w71 by Molmil
Crystal structure of the PDZ-C domain of E. coli RseP in complex with 12C7 Fab
Descriptor: Heavy chain of Fab, Light chain of Fab, Regulator of sigma-E protease RseP
Authors:Hirose, T, Katagiri, S, Nogi, T.
Deposit date:2021-12-02
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022

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