7Q3X
 
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7X1L
 | | Malate dehydrogenase from Geobacillus stearothermophilus (gs-MDH) delta E311 mutant complexed with Nicotinamide Adenine Dinucleotide (NAD+) | | Descriptor: | Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y. | | Deposit date: | 2022-02-24 | | Release date: | 2022-10-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Reducing substrate inhibition of malate dehydrogenase from Geobacillus stearothermophilus by C-terminal truncation.
Protein Eng.Des.Sel., 35, 2022
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5A1T
 | | Trichomonas vaginalis lactate dehydrogenase in complex with NADH and oxamate | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE, OXAMIC ACID | | Authors: | Steindel, P.A, Chen, E.H, Theobald, D.L. | | Deposit date: | 2015-05-05 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases.
Protein Sci., 25, 2016
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8AB3
 | | Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in complex with oxamate, NADH and FBP. | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, ... | | Authors: | Robin, A.Y, Girard, E, Madern, D. | | Deposit date: | 2022-07-04 | | Release date: | 2022-07-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.616 Å) | | Cite: | Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery.
Mol.Biol.Evol., 40, 2023
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8AB2
 | | Crystal Structure of the Lactate Dehydrogenase of Cyanobacterium Aponinum in its apo form. | | Descriptor: | 1,2-ETHANEDIOL, L-lactate dehydrogenase, TERBIUM(III) ION, ... | | Authors: | Robin, A.Y, Girard, E, Madern, D. | | Deposit date: | 2022-07-04 | | Release date: | 2022-08-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery.
Mol.Biol.Evol., 40, 2023
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4ZVV
 | | Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 | | Descriptor: | (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Li, Y, Chen, Z, Eigenbrot, C. | | Deposit date: | 2015-05-18 | | Release date: | 2016-05-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Nat.Chem.Biol., 12, 2016
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5UJK
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5ULV
 | | Malate dehydrogenase from Methylobacterium extorquens | | Descriptor: | CALCIUM ION, Malate dehydrogenase | | Authors: | Gonzalez, J.M. | | Deposit date: | 2017-01-25 | | Release date: | 2017-02-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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7XQN
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4ND1
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4ND3
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4ND4
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7BY9
 | | Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Nicotinamide Adenine Dinucleotide (NAD) | | Descriptor: | Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION | | Authors: | Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. | | Deposit date: | 2020-04-22 | | Release date: | 2021-03-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus.
J.Biochem., 170, 2021
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7BY8
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7BYA
 | | Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Adenosine 5'-Diphosphoribose (APR) | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Malate dehydrogenase, OXALOACETATE ION | | Authors: | Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. | | Deposit date: | 2020-04-22 | | Release date: | 2021-03-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus.
J.Biochem., 170, 2021
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2LDX
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3LDH
 | | A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes | | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID | | Authors: | White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G. | | Deposit date: | 1974-06-06 | | Release date: | 1977-04-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes.
J.Mol.Biol., 102, 1976
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3NEP
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6OR9
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6P6U
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6PBL
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2LDB
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3P7M
 | | Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4 | | Descriptor: | Malate dehydrogenase, PHOSPHATE ION | | Authors: | Osinski, T, Cymborowski, M, Zimmerman, M.D, Gordon, E, Grimshaw, S, Skarina, T, Chruszcz, M, Savchenko, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2010-10-12 | | Release date: | 2010-10-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4
To be Published
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2PWZ
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1LLC
 | | STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS CASEI AT 3.0 ANGSTROMS RESOLUTION | | Descriptor: | 1,6-di-O-phosphono-alpha-D-fructofuranose, L-LACTATE DEHYDROGENASE, SULFATE ION | | Authors: | Buehner, M, Hecht, H.J, Hensel, R. | | Deposit date: | 1988-11-21 | | Release date: | 1989-07-12 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS-CASEI AT 3A RESOLUTION.
Acta Crystallogr.,Sect.A, 40, 1984
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