6IRZ
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![BU of 6irz by Molmil](/molmil-images/mine/6irz) | Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA | Descriptor: | 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ... | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-15 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase. Science, 363, 2019
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2PMZ
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![BU of 2pmz by Molmil](/molmil-images/mine/2pmz) | Archaeal RNA polymerase from Sulfolobus solfataricus | Descriptor: | DNA-directed RNA polymerase subunit A, DNA-directed RNA polymerase subunit A", DNA-directed RNA polymerase subunit B, ... | Authors: | Murakami, K.S. | Deposit date: | 2007-04-23 | Release date: | 2008-02-12 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The X-ray crystal structure of RNA polymerase from Archaea Nature, 451, 2008
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4Q96
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![BU of 4q96 by Molmil](/molmil-images/mine/4q96) | CID of human RPRD1B in complex with an unmodified CTD peptide | Descriptor: | RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ... | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2014-04-29 | Release date: | 2014-06-04 | Last modified: | 2014-08-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4B02
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![BU of 4b02 by Molmil](/molmil-images/mine/4b02) | The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. | Deposit date: | 2012-06-27 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase. Virology, 432, 2012
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4Q94
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![BU of 4q94 by Molmil](/molmil-images/mine/4q94) | human RPRD1B CID in complex with a RPB1-CTD derived Ser2 phosphorylated peptide | Descriptor: | Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION, ... | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2014-04-29 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4NC8
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![BU of 4nc8 by Molmil](/molmil-images/mine/4nc8) | N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions | Descriptor: | DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | Authors: | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | Deposit date: | 2013-10-24 | Release date: | 2014-07-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
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4NC7
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![BU of 4nc7 by Molmil](/molmil-images/mine/4nc7) | N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | Authors: | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | Deposit date: | 2013-10-24 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
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4FLB
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![BU of 4flb by Molmil](/molmil-images/mine/4flb) | CID of human RPRD2 | Descriptor: | PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2012-06-14 | Release date: | 2012-08-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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2JLF
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![BU of 2jlf by Molmil](/molmil-images/mine/2jlf) | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2008-09-08 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
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2JLG
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![BU of 2jlg by Molmil](/molmil-images/mine/2jlg) | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE | Descriptor: | 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2008-09-09 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
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1IW7
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![BU of 1iw7 by Molmil](/molmil-images/mine/1iw7) | |
4FLA
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![BU of 4fla by Molmil](/molmil-images/mine/4fla) | Crystal structure of human RPRD1B, carboxy-terminal domain | Descriptor: | Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2012-06-14 | Release date: | 2012-08-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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1ARO
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![BU of 1aro by Molmil](/molmil-images/mine/1aro) | T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME | Descriptor: | MERCURY (II) ION, T7 LYSOZYME, T7 RNA POLYMERASE | Authors: | Steitz, T, Jeruzalmi, D. | Deposit date: | 1997-08-08 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme. EMBO J., 17, 1998
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7RIL
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![BU of 7ril by Molmil](/molmil-images/mine/7ril) | Crystal structure of hairpin polyamide Py-Im 1 bound to 5' CCTGACCAGG | Descriptor: | 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, ACETATE ION, non-template DNA, ... | Authors: | Oh, J, Dervan, P.B, Wang, D. | Deposit date: | 2021-07-20 | Release date: | 2022-01-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
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4QJF
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![BU of 4qjf by Molmil](/molmil-images/mine/4qjf) | |
1GX6
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![BU of 1gx6 by Molmil](/molmil-images/mine/1gx6) | |
1GX5
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![BU of 1gx5 by Molmil](/molmil-images/mine/1gx5) | |
3CJ2
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![BU of 3cj2 by Molmil](/molmil-images/mine/3cj2) | |
3CJ4
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![BU of 3cj4 by Molmil](/molmil-images/mine/3cj4) | |
3CJ3
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![BU of 3cj3 by Molmil](/molmil-images/mine/3cj3) | |
1ONV
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![BU of 1onv by Molmil](/molmil-images/mine/1onv) | NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1 | Descriptor: | Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a | Authors: | Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G. | Deposit date: | 2003-03-02 | Release date: | 2003-05-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1 Proc.Natl.Acad.Sci.USA, 100, 2003
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8BYQ
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![BU of 8byq by Molmil](/molmil-images/mine/8byq) | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | Deposit date: | 2022-12-14 | Release date: | 2023-05-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
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6YYS
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![BU of 6yys by Molmil](/molmil-images/mine/6yys) | Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core - State II, primary channel engaged and active site interfering | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Kouba, T, Koval, T, Krasny, L, Dohnalek, J. | Deposit date: | 2020-05-05 | Release date: | 2020-11-04 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase. Nat Commun, 11, 2020
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8BZ1
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![BU of 8bz1 by Molmil](/molmil-images/mine/8bz1) | RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | Deposit date: | 2022-12-14 | Release date: | 2023-05-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
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7NKX
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![BU of 7nkx by Molmil](/molmil-images/mine/7nkx) | RNA polymerase II-Spt4/5-nucleosome-Chd1 structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ... | Authors: | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | Deposit date: | 2021-02-19 | Release date: | 2021-08-25 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
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