7MX3
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![BU of 7mx3 by Molmil](/molmil-images/mine/7mx3) | Crystal structure of human RIPK3 complexed with GSK'843 | Descriptor: | 1,2-ETHANEDIOL, 3-(1,3-benzothiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine, Receptor-interacting serine/threonine-protein kinase 3 | Authors: | Davies, K.A, Czabotar, P.E. | Deposit date: | 2021-05-18 | Release date: | 2021-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
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7NIG
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![BU of 7nig by Molmil](/molmil-images/mine/7nig) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 | Descriptor: | 14-3-3 protein sigma, 2-bromanyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-02-12 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7NJA
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![BU of 7nja by Molmil](/molmil-images/mine/7nja) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1006 | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-02-16 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7NAC
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![BU of 7nac by Molmil](/molmil-images/mine/7nac) | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-21 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7NRC
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![BU of 7nrc by Molmil](/molmil-images/mine/7nrc) | Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A | Descriptor: | 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ... | Authors: | Pochopien, A.A, Beckert, B, Wilson, D.N. | Deposit date: | 2021-03-03 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of Gcn1 bound to stalled and colliding 80S ribosomes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NRK
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![BU of 7nrk by Molmil](/molmil-images/mine/7nrk) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1002F1 | Descriptor: | 14-3-3 protein sigma, 4-(4-methylimidazol-1-yl)benzaldehyde, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-03-04 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7NRL
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![BU of 7nrl by Molmil](/molmil-images/mine/7nrl) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1032 | Descriptor: | 14-3-3 protein sigma, 2-(hydroxymethyl)-5-(2-phenylimidazol-1-yl)phenol, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-03-04 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7MWI
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![BU of 7mwi by Molmil](/molmil-images/mine/7mwi) | Crystal structure of human BAZ2A | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, UNKNOWN ATOM OR ION | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-17 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
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7OHS
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![BU of 7ohs by Molmil](/molmil-images/mine/7ohs) | |
7OHW
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![BU of 7ohw by Molmil](/molmil-images/mine/7ohw) | |
7OHP
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![BU of 7ohp by Molmil](/molmil-images/mine/7ohp) | |
7OHV
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![BU of 7ohv by Molmil](/molmil-images/mine/7ohv) | |
7OHX
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![BU of 7ohx by Molmil](/molmil-images/mine/7ohx) | |
7OHR
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![BU of 7ohr by Molmil](/molmil-images/mine/7ohr) | Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Milkereit, P, Poell, G. | Deposit date: | 2021-05-11 | Release date: | 2021-11-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.72 Å) | Cite: | Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
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7NIF
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![BU of 7nif by Molmil](/molmil-images/mine/7nif) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound TCF521-011 | Descriptor: | 1-(4-methylphenyl)imidazole, 14-3-3 protein sigma, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-02-12 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7NJ8
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![BU of 7nj8 by Molmil](/molmil-images/mine/7nj8) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1007 | Descriptor: | 14-3-3 protein sigma, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-02-16 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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7NJ6
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![BU of 7nj6 by Molmil](/molmil-images/mine/7nj6) | 14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1005 | Descriptor: | 14-3-3 protein sigma, 4-[4-(trifluoromethyl)imidazol-1-yl]benzaldehyde, CALCIUM ION, ... | Authors: | Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. | Deposit date: | 2021-02-16 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
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1Q21
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7DBP
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![BU of 7dbp by Molmil](/molmil-images/mine/7dbp) | Linker histone defines structure and self-association behaviour of the 177 bp human chromosome | Descriptor: | DNA (175-MER), Histone H1.0, Histone H2A type 1-B/E, ... | Authors: | Wang, S, Vogirala, K.V, Soman, A, Liu, Z.B. | Deposit date: | 2020-10-21 | Release date: | 2020-12-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Linker histone defines structure and self-association behaviour of the 177 bp human chromatosome. Sci Rep, 11, 2021
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5GI0
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![BU of 5gi0 by Molmil](/molmil-images/mine/5gi0) | Crystal structure of RNA editing factor MORF9/RIP9 | Descriptor: | Multiple organellar RNA editing factor 9, chloroplastic | Authors: | Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-06-21 | Release date: | 2017-05-10 | Method: | X-RAY DIFFRACTION (2.044 Å) | Cite: | MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing Nat Plants, 3, 2017
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1MXE
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![BU of 1mxe by Molmil](/molmil-images/mine/1mxe) | Structure of the Complex of Calmodulin with the Target Sequence of CaMKI | Descriptor: | CALCIUM ION, Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I | Authors: | Clapperton, J.A, Martin, S.R, Smerdon, S.J, Gamblin, S.J, Bayley, P.M. | Deposit date: | 2002-10-02 | Release date: | 2002-12-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the Complex
of Calmodulin with the Target
Sequence of Calmodulin-Dependent
Protein Kinase I: Studies of the
Kinase Activation Mechanism Biochemistry, 41, 2002
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6JZD
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![BU of 6jzd by Molmil](/molmil-images/mine/6jzd) | Crystal structure of peptide-bound VASH2-SVBP complex | Descriptor: | GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | Authors: | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | Deposit date: | 2019-05-01 | Release date: | 2019-07-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.479 Å) | Cite: | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun, 10, 2019
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6JZC
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![BU of 6jzc by Molmil](/molmil-images/mine/6jzc) | Structural basis of tubulin detyrosination | Descriptor: | GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | Authors: | Chen, Z, Ling, Y, Zeyuan, G, Zhu, L. | Deposit date: | 2019-05-01 | Release date: | 2019-07-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer. Nat Commun, 10, 2019
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1QBK
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1W6R
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![BU of 1w6r by Molmil](/molmil-images/mine/1w6r) | Complex of TcAChE with galanthamine derivative | Descriptor: | (-)-GALANTHAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Greenblatt, H.M, Guillou, C, Guenard, D, Badet, B, Thal, C, Silman, I, Sussman, J.L. | Deposit date: | 2004-08-23 | Release date: | 2004-11-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. J.Am.Chem.Soc., 126, 2004
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