PDB: 1333 件ウェブページステータス検索Chemie searchBIRD

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3S74	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1-benzothiophene-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-10-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S75	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: Carbonic anhydrase 2, ZINC ION, furan-2-sulfonamide 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-10-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S76	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1H-imidazole-2-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-10-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S73	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-12-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S71	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1-benzofuran-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-10-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S97	PTPRZ CNTN1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, Receptor-type tyrosine-protein phosphatase zeta 著者 Bouyain, S. 登録日 2011-05-31 公開日 2011-09-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2971 Å) 主引用文献 A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells. Proc.Natl.Acad.Sci.USA, 108, 2011
3S8X	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-05-31 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3S9T	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-02 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SAP	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-{[(5-butylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SAX	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(5-ethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(5-ethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SBH	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-05 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SBI	Crystal structure of human carbonic anhydrase isozyme II with 4-[(2-pyrimidinylsulfanyl)acetyl]benzenesulfonamide 分子名称: 4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-05 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3B1B	The unique structure of wild type carbonic anhydrase alpha-CA1 from Chlamydomonas reinhardtii 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carbonic anhydrase 1, SULFATE ION, ... 著者 Shimizu, S, Takenaka, A. 登録日 2011-06-29 公開日 2011-11-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The unique structure of carbonic anhydrase alpha CA1 from Chlamydomonas reinhardtii Acta Crystallogr.,Sect.D, 67, 2011
3T5U	Crystal structure of the human carbonic anhydrase II in complex with N-hydroxy benzenesulfonamide 分子名称: Carbonic anhydrase 2, GLYCEROL, MERCURIBENZOIC ACID, ... 著者 Di Fiore, A, Maresca, A, Alterio, V, Supuran, C.T, De Simone, G. 登録日 2011-07-28 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem.Commun.(Camb.), 47, 2011
3T5Z	Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, N-methoxybenzenesulfonamide, ... 著者 Di Fiore, A, Maresca, A, Alterio, V, Supuran, C.T, De Simone, G. 登録日 2011-07-28 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem.Commun.(Camb.), 47, 2011
3T82	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates 分子名称: 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-glucopyranose, Carbonic anhydrase 2, ZINC ION 著者 Hofmann, A, Wang, C.K. 登録日 2011-08-01 公開日 2011-10-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3T84	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates 分子名称: 4-O-acetyl-6-O-sulfamoyl-alpha-D-galactopyranose, Carbonic anhydrase 2, ZINC ION 著者 Hofmann, A, Wang, C.K. 登録日 2011-08-01 公開日 2011-10-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3T85	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates 分子名称: 3,4-di-O-acetyl-6-O-sulfamoyl-alpha-D-mannopyranose, Carbonic anhydrase 2, ZINC ION 著者 Hofmann, A, Wang, C.K. 登録日 2011-08-01 公開日 2011-10-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3T83	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates 分子名称: 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-alpha-D-glucopyranose, 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-beta-D-glucopyranose, Carbonic anhydrase 2, ... 著者 Hofmann, A, Wang, C.K. 登録日 2011-08-01 公開日 2011-10-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
3TMJ	Joint X-ray/neutron structure of human carbonic anhydrase II at pH 7.8 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Fisher, Z. 登録日 2011-08-31 公開日 2011-11-09 最終更新日 2023-09-13 実験手法 NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION 主引用文献 Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network "Switch" Is Observed between pH 7.8 and 10.0. Biochemistry, 50, 2011
3TVO	Human Carbonic Anhydrase II Proton Transfer Double Mutant 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 Mikulski, R.M. 登録日 2011-09-20 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II. Biochemistry, 52, 2013
3TVN	Human Carbonic Anhydrase II Proton Transfer Mutant 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Mikulski, R.L, West, D.M, Sippel, K.H, Avvaru, B.S, Chingkuang, T, McKenna, R. 登録日 2011-09-20 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II. Biochemistry, 52, 2013
3U3A	structure of Human Carbonic Anhydrase II V143I 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 West, D, Mckenna, R. 登録日 2011-10-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.549 Å) 主引用文献 Structural Analysis of Human Carbonic Anhydrase II Binding Pocket To be Published
3U45	Human Carbonic Anhydrase II V143A 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 West, D, Mckenna, R. 登録日 2011-10-07 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Structural Modification of the hydrophobic pocket in Human Carbonic Anhydrase II To be Published
3U47	Human Carbonic Anhydrase II V143L 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 West, D, Mckenna, R. 登録日 2011-10-07 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural modification of the hydrophobic pocket of Human Carbonic Anhydrase II To be Published

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