3TMJ

Joint X-ray/neutron structure of human carbonic anhydrase II at pH 7.8

Summary for 3TMJ

DescriptorCarbonic anhydrase 2, ZINC ION (3 entities in total)
Functional Keywordsh/d exchanged, joint neutron/x-ray refinement, lyase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight29136.19
Authors
Fisher, Z. (deposition date: 2011-08-31, release date: 2011-11-09, Last modification date: 2018-06-13)
Primary citation
Fisher, Z.,Kovalevsky, A.Y.,Mustyakimov, M.,Silverman, D.N.,McKenna, R.,Langan, P.
Neutron Structure of Human Carbonic Anhydrase II: A Hydrogen-Bonded Water Network "Switch" Is Observed between pH 7.8 and 10.0.
Biochemistry, 50:9421-9423, 2011
PubMed: 21988105 (PDB entries with the same primary citation)
DOI: 10.1021/bi201487b
MImport into Mendeley
Experimental method
NEUTRON DIFFRACTION (2 Å)
X-RAY DIFFRACTION
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.180100.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3tmj
no rotation
Molmil generated image of 3tmj
rotated about x axis by 90°
Molmil generated image of 3tmj
rotated about y axis by 90°