8XW1
| Cryo-EM structure of OSCA1.2-V335W-DDM state | Descriptor: | Calcium permeable stress-gated cation channel 1 | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.49 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XW0
| Cryo-EM structure of OSCA3.1-GDN state | Descriptor: | CSC1-like protein ERD4, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | Authors: | Zhang, Y, Han, Y. | Deposit date: | 2024-01-15 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
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8XVZ
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8XVY
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8XVX
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8XUV
| Cryo-EM structure of tomato NRC2 filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | Deposit date: | 2024-01-14 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR. Nature, 2024
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8XUQ
| Cryo-EM structure of tomato NRC2 tetramer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | Deposit date: | 2024-01-14 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR. Nature, 2024
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8XUO
| Cryo-EM structure of tomato NRC2 dimer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, NRC2 | Authors: | Sun, Y, Ma, S.C, Chai, J.J. | Deposit date: | 2024-01-13 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Oligomerization-mediated autoinhibition and cofactor binding of a plant NLR. Nature, 2024
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8XU4
| The Crystal Structure of MAPK2 from Biortus. | Descriptor: | MALONIC ACID, MAP kinase-activated protein kinase 2 | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. | Deposit date: | 2024-01-12 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The Crystal Structure of MAPK2 from Biortus. To Be Published
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8XSZ
| Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSY
| Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XSX
| Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XS5
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8XS4
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8XS0
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8XRY
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8XRU
| The crystal structure of a GH3 enzyme CcBgl3B with glycerol | Descriptor: | CALCIUM ION, GH3 enzyme CcBgl3B, GLYCEROL | Authors: | Su, J.Y. | Deposit date: | 2024-01-08 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | A trapped covalent intermediate as a key catalytic element in the hydrolysis of a GH3 beta-glucosidase: An X-ray crystallographic and biochemical study. Int.J.Biol.Macromol., 265, 2024
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8XR3
| Crystal structure of AKRtyl-apo2 | Descriptor: | Aldo/keto reductase | Authors: | Lin, S, Dai, S, Xiao, Z. | Deposit date: | 2024-01-06 | Release date: | 2024-04-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D. Nat Commun, 15, 2024
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8XQB
| Mature virion portal vertex of bacteriophage lambda | Descriptor: | Capsid decoration protein, Head completion protein, Head-tail connector protein FII, ... | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-05 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.07 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XPV
| The Crystal Structure of EphA2 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, Ephrin type-A receptor 2, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Xu, Y. | Deposit date: | 2024-01-04 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of EphA2 from Biortus. To Be Published
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8XPU
| Overall structure of the LAT1-4F2hc bound with JPH203 | Descriptor: | (2~{S})-2-azanyl-3-[4-[(5-azanyl-2-phenyl-1,3-benzoxazol-7-yl)methoxy]-3,5-bis(chloranyl)phenyl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 5 of Amino acid transporter heavy chain SLC3A2, ... | Authors: | Hu, Z, Yan, R. | Deposit date: | 2024-01-04 | Release date: | 2024-07-17 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for the inhibition mechanism of LAT1-4F2hc complex by JPH203. Cell Discov, 10, 2024
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8XPN
| The Crystal Structure of USP8 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ubiquitin carboxyl-terminal hydrolase 8, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Wang, J. | Deposit date: | 2024-01-04 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of USP8 from Biortus. To Be Published
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8XPM
| Mature virion portal of phage lambda with DNA | Descriptor: | DNA (104-MER), DNA (92-MER), Head completion protein, ... | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-04 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XPE
| Crystal structure of Tris-bound TsaBgl (DATA III) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, beta-glucosidase | Authors: | Nam, K.H. | Deposit date: | 2024-01-03 | Release date: | 2024-01-31 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural analysis of Tris binding in beta-glucosidases. Biochem.Biophys.Res.Commun., 700, 2024
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8XPD
| Crystal structure of Tris-bound TsaBgl (DATA II) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, beta-glucosidase | Authors: | Nam, K.H. | Deposit date: | 2024-01-03 | Release date: | 2024-01-31 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural analysis of Tris binding in beta-glucosidases. Biochem.Biophys.Res.Commun., 700, 2024
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