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8OE5
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BU of 8oe5 by Molmil
Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3
Descriptor: Beta-lactamase, CITRATE ANION, GLYCEROL
Authors:Sun, J, Chikunova, A, Ubbink, M.
Deposit date:2023-03-10
Release date:2023-08-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
6AQU
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BU of 6aqu by Molmil
Crystal Structure of Plasmodium falciparum purine nucleoside phosphorylase: The M183L mutant
Descriptor: PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Harijan, R.K, Ducati, R.G, Namanja-Magliano, H.A, Bonanno, J.B, Almo, S.C, Schramm, V.L.
Deposit date:2017-08-21
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Genetic resistance to purine nucleoside phosphorylase inhibition inPlasmodium falciparum.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AVC
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BU of 6avc by Molmil
Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
Descriptor: Potassium channel toxin alpha-KTx 1.5
Authors:Gewe, M.M, Rupert, P, Strong, R.K.
Deposit date:2017-09-01
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
8OE1
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BU of 8oe1 by Molmil
Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5
Descriptor: Beta-lactamase, GLYCEROL
Authors:Sun, J, Chikunova, A, Ubbink, M.
Deposit date:2023-03-10
Release date:2023-08-23
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
7UR6
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BU of 7ur6 by Molmil
Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-04-21
Release date:2023-04-26
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664
To Be Published
8P5T
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BU of 8p5t by Molmil
Single particle cryo-EM structure of the homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum
Descriptor: 2-oxoglutarate dehydrogenase E1/E2 component, ACETYL COENZYME *A, MAGNESIUM ION, ...
Authors:Yang, L, Mechaly, A.M, Bellinzoni, M.
Deposit date:2023-05-24
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.17 Å)
Cite:High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
8DI7
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BU of 8di7 by Molmil
CMY-2
Descriptor: Beta-lactamase, SULFATE ION
Authors:Ahmadvand, P, Call, D.R.
Deposit date:2022-06-28
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural characterization of CMY-2 and its interactions with ampicillin and the cephalosporins - ceftiofur, DFC, DFC-dimer, DFC-cysteine, and nitrocefin
To Be Published
8P5V
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BU of 8p5v by Molmil
Single particle cryo-EM structure of homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum in complex with the product succinyl-CoA
Descriptor: 2-oxoglutarate dehydrogenase E1/E2 component, ACETYL COENZYME *A, MAGNESIUM ION, ...
Authors:Yang, L, Mechaly, A.M, Bellinzoni, M.
Deposit date:2023-05-24
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
6ATU
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BU of 6atu by Molmil
Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
Descriptor: Elafin
Authors:Gewe, M.M, Rupert, P, Strong, R.K.
Deposit date:2017-08-29
Release date:2018-02-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
6AS7
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BU of 6as7 by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2017-08-23
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Activity and fidelity of human DNA polymerase alpha depend on primer structure.
J. Biol. Chem., 293, 2018
8P67
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BU of 8p67 by Molmil
Crystal structure of Thermothelomyces thermophila (double mutant EE) in complex with aldotetrauronic acid
Descriptor: 1,2-ETHANEDIOL, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, GH30 family xylanase, ...
Authors:Dimarogona, M, Pentari, C, Kosinas, C, Topakas, E.
Deposit date:2023-05-25
Release date:2024-05-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural and molecular insights into a bifunctional glycoside hydrolase 30 xylanase specific to glucuronoxylan.
Biotechnol.Bioeng., 121, 2024
7SZ2
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BU of 7sz2 by Molmil
Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
Authors:Ayanath Kuttiyatveetil, J.R, Pascal, J.M.
Deposit date:2021-11-25
Release date:2022-10-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose).
Cell Rep, 41, 2022
8DOZ
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BU of 8doz by Molmil
Protective antibody against gonococcal lipooligosaccharide
Descriptor: ACETATE ION, Fab 2C7 lambda light chain, Fab 2C7, ...
Authors:Beernink, P.T.
Deposit date:2022-07-14
Release date:2023-06-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protective antibody against gonococcal lipooligosaccharide bound to a peptide mimetic vaccine antigen
TBD
8P7G
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BU of 8p7g by Molmil
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
Descriptor: Paired mesoderm homeobox protein 2B
Authors:Russo, L, Diana, D, Fattorusso, R.
Deposit date:2023-05-30
Release date:2024-05-15
Last modified:2024-06-26
Method:SOLUTION NMR
Cite:Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS.
Chem Sci, 15, 2024
8PWU
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BU of 8pwu by Molmil
PfRH5 bound to monoclonal antibody MAD10-255
Descriptor: Reticulocyte-binding protein homolog 5, monoclonal antibody MAD10-255
Authors:Farrell, B, Higgins, M.K.
Deposit date:2023-07-21
Release date:2024-06-05
Method:X-RAY DIFFRACTION (3.148 Å)
Cite:PfRH5 bound to monoclonal antibody MAD10-255
To Be Published
5XTM
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BU of 5xtm by Molmil
Crystal structure of PhoRpp38 bound to a K-turn in P12.2 helix
Descriptor: 50S ribosomal protein L7Ae, MAGNESIUM ION, RNA (47-MER)
Authors:Oshima, K, Kimura, M.
Deposit date:2017-06-20
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the archaeal RNase P protein Rpp38 in complex with RNA fragments containing a K-turn motif.
Acta Crystallogr F Struct Biol Commun, 74, 2018
5XO3
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BU of 5xo3 by Molmil
Thanatin M21F Free
Descriptor: Thanatin
Authors:Sinha, S, Bhattacharjya, S.
Deposit date:2017-05-26
Release date:2018-06-27
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Thanatin M21F Free
To Be Published
5XOB
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BU of 5xob by Molmil
Crystal structure of apo TiaS (tRNAIle2 agmatidine synthetase)
Descriptor: MAGNESIUM ION, ZINC ION, tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS
Authors:Dong, J.
Deposit date:2017-05-27
Release date:2018-08-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure of tRNA-Modifying Enzyme TiaS and Motions of Its Substrate Binding Zinc Ribbon.
J. Mol. Biol., 430, 2018
7SZ3
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BU of 7sz3 by Molmil
Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ADPr
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, PHOSPHATE ION, ...
Authors:Ayanath Kuttiyatveetil, J.R, Pascal, J.M.
Deposit date:2021-11-25
Release date:2022-10-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose).
Cell Rep, 41, 2022
5XQP
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BU of 5xqp by Molmil
Crystal structure of Notched-fin eelpout type III antifreeze protein (NFE6, AFP), P212121 form
Descriptor: Ice-structuring protein, SULFATE ION
Authors:Adachi, M, Shimizu, R, Shibazaki, C, Kondo, H, Tsuda, S.
Deposit date:2017-06-07
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7UJ3
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BU of 7uj3 by Molmil
Crystal structure of Human respiratory syncytial virus F variant (construct pXCS847A)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RSV variant (construct pXCS847A) F1, RSV variant (construct pXCS847A) F2, ...
Authors:Han, S, Ammirati, M.
Deposit date:2022-03-30
Release date:2023-04-19
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine.
Sci Transl Med, 15, 2023
7UVG
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BU of 7uvg by Molmil
First cohesin of Sca5 from Ruminococcus bromii
Descriptor: 1,2-ETHANEDIOL, Coh5, IODIDE ION
Authors:Cerqueira, F, Koropatkin, N.
Deposit date:2022-05-01
Release date:2023-05-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structures of Sca5 cohesin modules from Ruminococcus bromii
To Be Published
7UOJ
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BU of 7uoj by Molmil
The CryoEM structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Nguyen, D.N, Tolbert, W.D, Pazgier, M.
Deposit date:2022-04-13
Release date:2023-05-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:The structure of N49-P9.6-FR3 and PGT121 Fabs in complex with BG505 SOSIP
To Be Published
8E2C
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BU of 8e2c by Molmil
N-terminal domain of S. aureus GpsB in complex with PBP4 fragment
Descriptor: Cell cycle protein GpsB, PBP4
Authors:Sacco, M, Chen, Y.
Deposit date:2022-08-14
Release date:2023-08-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB.
Elife, 13, 2024
7UH9
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BU of 7uh9 by Molmil
NMR structure of the cNTnC-cTnI chimera bound to W8
Descriptor: CALCIUM ION, N-(7-aminoheptyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ...
Authors:Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D.
Deposit date:2022-03-26
Release date:2022-06-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022

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PDB entries from 2024-11-06

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