4D26
 
 | | Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA,ADP and Pi | | Descriptor: | 5'-R(*UP*GP*AP*CP*AP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, BMVLG PROTEIN, ... | | Authors: | Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S. | | Deposit date: | 2014-05-07 | | Release date: | 2014-06-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts.
Cell(Cambridge,Mass.), 157, 2014
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4CDG
 | | Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BLOOM SYNDROME PROTEIN, NANOBODY, ... | | Authors: | Newman, J.A, Savitsky, P, Allerston, C.K, Pike, A.C.W, Pardon, E, Steyaert, J, Arrowsmith, C.H, von Delft, F, Bountra, C, Edwards, A, Gileadi, O. | | Deposit date: | 2013-10-31 | | Release date: | 2013-11-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.794 Å) | | Cite: | Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes.
Nucleic Acids Res., 43, 2015
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4DDX
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4DDU
 | | Thermotoga maritima reverse gyrase, C2 FORM 1 | | Descriptor: | Reverse gyrase, ZINC ION | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2012-01-19 | | Release date: | 2012-12-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
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6YHR
 | | Crystal structure of Werner syndrome helicase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Werner syndrome ATP-dependent helicase, ZINC ION | | Authors: | Newman, J.A, Gavard, A.E, Savitsky, P, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | Deposit date: | 2020-03-30 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.
Life Sci Alliance, 4, 2021
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6ZNS
 | | Crystal Structure of DUF1998 helicase MrfA | | Descriptor: | Uncharacterized ATP-dependent helicase YprA, ZINC ION | | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | | Deposit date: | 2020-07-06 | | Release date: | 2020-11-25 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases.
Nucleic Acids Res., 49, 2021
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6ZM2
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6ZNP
 | | Crystal Structure of DUF1998 helicase MrfA bound to DNA | | Descriptor: | CITRIC ACID, Uncharacterized ATP-dependent helicase YprA, ZINC ION, ... | | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | | Deposit date: | 2020-07-06 | | Release date: | 2020-11-25 | | Last modified: | 2021-01-20 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases.
Nucleic Acids Res., 49, 2021
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6ZNQ
 | | Crystal Structure of DUF1998 helicase MrfA bound to DNA and AMPPNP | | Descriptor: | CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Uncharacterized ATP-dependent helicase YprA, ... | | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | | Deposit date: | 2020-07-06 | | Release date: | 2020-11-25 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.34 Å) | | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases.
Nucleic Acids Res., 49, 2021
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6ZWW
 | | Crystal structure of E. coli RNA helicase HrpA in complex with RNA | | Descriptor: | ATP-dependent RNA helicase HrpA, CALCIUM ION, ssRNA | | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-07-29 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6ZWX
 | | Crystal structure of E. coli RNA helicase HrpA | | Descriptor: | ATP-dependent RNA helicase HrpA | | Authors: | Grass, L.M, Wollenhaupt, J, Barthel, T, Loll, B, Wahl, M.C. | | Deposit date: | 2020-07-29 | | Release date: | 2021-06-30 | | Last modified: | 2021-08-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7A8R
 | | Structure of RecQL from Bos taurus | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, MAGNESIUM ION, ... | | Authors: | Rety, S, Chen, W.F, Xi, X.G. | | Deposit date: | 2020-08-30 | | Release date: | 2021-10-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers.
Cell Rep, 36, 2021
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7AUD
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7AUC
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7AQO
 | | yeast THO-Sub2 complex dimer | | Descriptor: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | | Deposit date: | 2020-10-22 | | Release date: | 2020-12-02 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
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5ZC9
 | | Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex | | Descriptor: | (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | | Authors: | Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T. | | Deposit date: | 2018-02-16 | | Release date: | 2019-01-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Mol. Cell, 73, 2019
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6AC6
 | | Ab initio crystal structure of Selenomethionine labelled Mycobacterium smegmatis Mfd | | Descriptor: | Mycobacterium smegmatis Mfd, SULFATE ION | | Authors: | Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R. | | Deposit date: | 2018-07-25 | | Release date: | 2019-08-28 | | Method: | X-RAY DIFFRACTION (2.989 Å) | | Cite: | Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
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6B4I
 | | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nucleoporin GLE1, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.619 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6B4K
 | | Crystal structure of human DDX19B(AMPPNP) | | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, MALONATE ION, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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6ACA
 | | Crystal structure of Mycobacterium tuberculosis Mfd at 3.6 A resolution | | Descriptor: | Mycobacterium tuberculosis Mfd | | Authors: | Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R. | | Deposit date: | 2018-07-26 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
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6AC8
 | | Crystal structure of Mycobacterium smegmatis Mfd at 2.75 A resolution | | Descriptor: | Mycobacterium smegmatis Mfd, SULFATE ION | | Authors: | Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R. | | Deposit date: | 2018-07-25 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
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6ACX
 | | Crystal structure of Mycobacterium smegmatis Mfd in complex with ADP + Pi at 3.5 A resolution. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Mycobacterium smegmatis Mfd, PHOSPHATE ION, ... | | Authors: | Putta, S, Fox, G.C, Walsh, M.A, Rao, D.N, Nagaraja, V, Natesh, R. | | Deposit date: | 2018-07-27 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis for nucleotide-mediated remodelling mechanism of Mycobacterium Mfd
To Be Published
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6BB8
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6B4J
 | | Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex | | Descriptor: | ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, Nucleoporin GLE1, ... | | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | | Deposit date: | 2017-09-26 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
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7YMF
 | | Crystal Structure of DDX3X449_450ET>DP | | Descriptor: | ATP-dependent RNA helicase DDX3X | | Authors: | Xiong, J. | | Deposit date: | 2022-07-28 | | Release date: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of DDX3X449_450ET>DP
To Be Published
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