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2DO5
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BU of 2do5 by Molmil
Solution structure of the SAP domain of human splicing factor 3B subunit 2
Descriptor: Splicing factor 3B subunit 2
Authors:Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-27
Release date:2007-04-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the SAP domain of human splicing factor 3B subunit 2
To be Published
2DN5
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BU of 2dn5 by Molmil
Solution Structure of RSGI RUH-057, a GTF2I domain in human cDNA
Descriptor: General transcription factor II-I repeat domain-containing protein 1
Authors:Doi-Katayama, Y, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-25
Release date:2006-10-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of RSGI RUH-057, a GTF2I domain in human cDNA
To be Published
2ND1
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BU of 2nd1 by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_3 peptide
Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-19
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2DHS
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BU of 2dhs by Molmil
Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with DNA and RNA
Descriptor: CUG triplet repeat RNA-binding protein 1
Authors:Xia, Y.L, Jun, K.Y, Zhu, Q, Han, X.G, Zhang, H, Timchenko, L, Swanson, M, Gao, X.L.
Deposit date:2006-03-25
Release date:2007-04-24
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with DNA and RNA
To be Published
2DW4
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BU of 2dw4 by Molmil
Crystal structure of human LSD1 at 2.3 A resolution
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
Authors:Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-08-02
Release date:2007-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25A
Biochem.Biophys.Res.Commun., 366, 2008
2FBV
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BU of 2fbv by Molmil
WRN exonuclease, Mn complex
Descriptor: MANGANESE (II) ION, Werner syndrome helicase
Authors:Perry, J.J.
Deposit date:2005-12-10
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
2FBT
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BU of 2fbt by Molmil
WRN exonuclease
Descriptor: ACETIC ACID, Werner syndrome helicase
Authors:Perry, J.J.
Deposit date:2005-12-10
Release date:2006-04-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.
Nat.Struct.Mol.Biol., 13, 2006
2CR9
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BU of 2cr9 by Molmil
Solution structure of WGR domain of poly(ADP-ribose) polymerase-1
Descriptor: Poly [ADP-ribose] polymerase-1
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of WGR domain of poly(ADP-ribose) polymerase-1
To be published
2CSF
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BU of 2csf by Molmil
Solution structure of the second CUT domain of human SATB2
Descriptor: DNA-binding protein SATB2
Authors:Inoue, K, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-21
Release date:2005-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second CUT domain of human SATB2
To be Published
2NML
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BU of 2nml by Molmil
Crystal structure of HEF2/ERH at 1.55 A resolution
Descriptor: Enhancer of rudimentary homolog
Authors:Jin, T.C, Guo, F, Serebriiskii, I.G, Howard, A.J, Zhang, Y.Z.
Deposit date:2006-10-21
Release date:2006-10-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A 1.55 A resolution X-ray crystal structure of HEF2/ERH and insights into its transcriptional and cell-cycle interaction networks.
Proteins, 68, 2007
2CSH
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BU of 2csh by Molmil
Solution structure of tandem repeat of the zf-C2H2 domains of human zinc finger protein 297B
Descriptor: ZINC ION, Zinc finger protein 297B
Authors:Inoue, K, Saitoh, K, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-21
Release date:2005-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of tandem repeat of the zf-C2H2 domains of human zinc finger protein 297B
To be Published
2ND0
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BU of 2nd0 by Molmil
Solution NMR structures of BRD4 ET domain with LANA peptide
Descriptor: Bromodomain-containing protein 4, LANA
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-18
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2N80
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BU of 2n80 by Molmil
p75NTR DD:RhoGDI
Descriptor: Rho GDP-dissociation inhibitor 1, Tumor necrosis factor receptor superfamily member 16
Authors:Lin, Z, Ibanez, C.F.
Deposit date:2015-09-30
Release date:2015-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
2NCZ
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BU of 2ncz by Molmil
Solution NMR structures of BRD4 ET domain in complex with NSD3_1 peptide
Descriptor: Bromodomain-containing protein 4, Histone-lysine N-methyltransferase NSD3
Authors:Zeng, L, Zhou, M.
Deposit date:2016-04-18
Release date:2016-06-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
Structure, 24, 2016
2QZV
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BU of 2qzv by Molmil
Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution
Descriptor: Major vault protein
Authors:Anderson, D.H, Kickhoefer, V.A, Sievers, S.A, Rome, L.H, Eisenberg, D.
Deposit date:2007-08-17
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (9 Å)
Cite:Draft crystal structure of the vault shell at 9-A resolution.
Plos Biol., 5, 2007
2G76
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BU of 2g76 by Molmil
Crystal structure of human 3-phosphoglycerate dehydrogenase
Descriptor: D-3-phosphoglycerate dehydrogenase, D-MALATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Turnbull, A.P, Salah, E, Savitsky, P, Gileadi, O, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-02-27
Release date:2006-03-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human 3-phosphoglycerate dehydrogenase
To be Published
2FMM
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BU of 2fmm by Molmil
Crystal Structure of EMSY-HP1 complex
Descriptor: Chromobox protein homolog 1, Protein EMSY, SULFATE ION
Authors:Huang, Y.
Deposit date:2006-01-09
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
Structure, 14, 2006
2QQS
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BU of 2qqs by Molmil
JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
Descriptor: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
Authors:Lee, J, Botuyan, M.V, Mer, G.
Deposit date:2007-07-26
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
2QUT
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BU of 2qut by Molmil
Dihydroxyacetone phosphate enamine intermediate in fructose-1,6-bisphosphate aldolase from rabbit muscle
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase A
Authors:St-Jean, M, Sygusch, J.
Deposit date:2007-08-06
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase
J.Biol.Chem., 282, 2007
2RAN
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BU of 2ran by Molmil
RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Concha, N.O, Head, J.F, Kaetzel, M.A, Dedman, J.R, Seaton, B.A.
Deposit date:1994-09-01
Release date:1994-11-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Rat annexin V crystal structure: Ca(2+)-induced conformational changes.
Science, 261, 1993
2G9A
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BU of 2g9a by Molmil
Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
Descriptor: Histone H3, WD-repeat protein 5
Authors:Chai, J, Han, Z, Wang, H, Shen, Y.
Deposit date:2006-03-06
Release date:2006-09-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
To be published
6EIN
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BU of 6ein by Molmil
Crystal structure of KDM5B in complex with S49365a.
Descriptor: 1,2-ETHANEDIOL, 8-[4-[2-(4-propanoylpiperazin-1-yl)ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ...
Authors:Srikannathasan, V, Newman, J.A, Szykowska, A, Wright, M, Ruda, G.F, Vazquez-Rodriguez, S.A, Kupinska, K, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Huber, K, von Delft, F.
Deposit date:2017-09-19
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of KDM5B in complex with S49365a.
To Be Published
6E93
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BU of 6e93 by Molmil
Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA
Descriptor: DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ...
Authors:Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A.
Deposit date:2018-07-31
Release date:2018-11-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.747 Å)
Cite:Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38.
J. Biol. Chem., 293, 2018
6EOC
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BU of 6eoc by Molmil
Crystal structure of AMPylated GRP78 in apo form (Crystal form 2)
Descriptor: 78 kDa glucose-regulated protein, CITRATE ANION, SULFATE ION
Authors:Yan, Y, Preissler, S, Ron, D, Read, R.J.
Deposit date:2017-10-09
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
Elife, 6, 2017
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
Authors:De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018

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