PDB: 45118 resultsInfo pagesStatus searchChemie searchBIRD

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3WGV	Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. Deposit date: 2013-08-09 Release date: 2013-10-09 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
3WGU	Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. Deposit date: 2013-08-09 Release date: 2013-10-09 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state Nature, 502, 2013
8FT4	Multicrystal structure of Na+, leucine-bound LeuT determined at 5 keV Descriptor: CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ... Authors: Karasawa, A, Liu, H, Quick, M, Hendrickson, A.H, Liu, Q. Deposit date: 2023-01-11 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (4 Å) Cite: Crystallographic characterization of sodium ions in a bacterial leucine/sodium symporter To be Published
8HYA	Cryo-EM structure of Arabidopsis thaliana SOS1 in an occluded state, with expanded TMD Descriptor: HEXADECANE, Sodium/hydrogen exchanger 7 Authors: Wang, Y, Zhao, Y, Gao, Y. Deposit date: 2023-01-06 Release date: 2023-08-09 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Architecture and autoinhibitory mechanism of the plasma membrane Na + /H + antiporter SOS1 in Arabidopsis. Nat Commun, 14, 2023
2OD3	Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... Authors: Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E. Deposit date: 2006-12-21 Release date: 2007-04-10 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis of na+ activation mimicry in murine thrombin. J.Biol.Chem., 282, 2007
4HUN	MATE transporter NorM-NG in complex with R6G and monobody Descriptor: Multidrug efflux protein, RHODAMINE 6G, protein B Authors: Lu, M. Deposit date: 2012-11-02 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.59 Å) Cite: Structures of a Na+-coupled, substrate-bound MATE multidrug transporter. Proc.Natl.Acad.Sci.USA, 110, 2013
4HUL	MATE transporter NorM-NG in complex with Cs+ and monobody Descriptor: CESIUM ION, Multidrug efflux protein, Protein B Authors: Lu, M. Deposit date: 2012-11-02 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.81 Å) Cite: Structures of a Na+-coupled, substrate-bound MATE multidrug transporter. Proc.Natl.Acad.Sci.USA, 110, 2013
4HUK	MATE transporter NorM-NG in complex with TPP and monobody Descriptor: Multidrug efflux protein, Protein B, TETRAPHENYLPHOSPHONIUM Authors: Lu, M. Deposit date: 2012-11-02 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.59 Å) Cite: Structures of a Na+-coupled, substrate-bound MATE multidrug transporter. Proc.Natl.Acad.Sci.USA, 110, 2013
4HUM	MATE transporter NorM-NG in complex with ethidium and monobody Descriptor: ETHIDIUM, Multidrug efflux protein, Protein B Authors: Lu, M. Deposit date: 2012-11-02 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.49 Å) Cite: Structures of a Na+-coupled, substrate-bound MATE multidrug transporter. Proc.Natl.Acad.Sci.USA, 110, 2013
6BV7	NMR structure of Sodium/Calcium Exchanger 1 (NCX1) Two-helix Bundle (THB) domain Descriptor: Sodium/calcium exchanger 1 Authors: Yuan, J, Yuan, C, Bruschweiler, R. Deposit date: 2017-12-12 Release date: 2018-06-20 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: The Intracellular Loop of the Na+/Ca2+Exchanger Contains an "Awareness Ribbon"-Shaped Two-Helix Bundle Domain. Biochemistry, 57, 2018
6NUU	Structure of Calcineurin mutant in complex with NHE1 peptide Descriptor: CALCIUM ION, Calcineurin subunit B type 1, DI(HYDROXYETHYL)ETHER, ... Authors: Wang, X, Page, R, Peti, W. Deposit date: 2019-02-02 Release date: 2019-07-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin. Nat Commun, 10, 2019
4OFN	Monoclinic NaGST1 Descriptor: GLUTATHIONE, Glutathione S-transferase-1 Authors: Asojo, O.A. Deposit date: 2014-01-15 Release date: 2014-12-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione. Acta Crystallogr F Struct Biol Commun, 70, 2014
7W9K	Cryo-EM structure of human Nav1.7-beta1-beta2 complex at 2.2 angstrom resolution Descriptor: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... Authors: Yan, N, Huang, G, Liu, D, Wei, P, Shen, H. Deposit date: 2021-12-09 Release date: 2022-06-01 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
8OTW	Cryo-EM structure of Strongylocentrotus purpuratus SLC9C1 in presence of cAMP Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sperm-specific sodium proton exchanger Authors: Yeo, H, Mehta, V, Gulati, A, Drew, D. Deposit date: 2023-04-21 Release date: 2023-11-01 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (3.68 Å) Cite: Structure and electromechanical coupling of a voltage-gated Na + /H + exchanger. Nature, 623, 2023
5IP5	Human DJ-1 complexed with Na-K-tartrate Descriptor: L(+)-TARTARIC ACID, Protein deglycase DJ-1 Authors: Lee, S, Cha, S.-S, An, Y.J. Deposit date: 2016-03-09 Release date: 2017-03-15 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Human DJ-1 complexed with Na-K-tartrate To Be Published
7DTD	Voltage-gated sodium channel Nav1.1 and beta4 Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 1 subunit alpha, ... Authors: Yan, N, Pan, X, Li, Z, Huang, G. Deposit date: 2021-01-04 Release date: 2021-04-07 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Comparative structural analysis of human Na v 1.1 and Na v 1.5 reveals mutational hotspots for sodium channelopathies. Proc.Natl.Acad.Sci.USA, 118, 2021
3TI5	Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with Zanamivir Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... Authors: Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. Deposit date: 2011-08-20 Release date: 2011-11-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
3TI6	Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with oseltamivir Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. Deposit date: 2011-08-20 Release date: 2011-11-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
2KXW	Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2 Descriptor: Calmodulin, Sodium channel protein type 2 subunit alpha Authors: Feldkamp, M.D, Yu, L, Shea, M.A. Deposit date: 2010-05-13 Release date: 2011-04-13 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural and Energetic Determinants of Apo Calmodulin Binding to the IQ Motif of the Na(V)1.2 Voltage-Dependent Sodium Channel. Structure, 19, 2011
3TI8	Crystal structure of influenza A virus neuraminidase N5 complexed with laninamivir Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, ... Authors: Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. Deposit date: 2011-08-20 Release date: 2011-11-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.601 Å) Cite: Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
3TI3	Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with laninamivir Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, ... Authors: Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. Deposit date: 2011-08-20 Release date: 2011-11-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
3TI4	Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with laninamivir octanoate Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-9-O-octanoyl-D-glycero-D-galacto-non-2-enonic acid, ACETATE ION, ... Authors: Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. Deposit date: 2011-08-20 Release date: 2011-11-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.602 Å) Cite: Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition Plos Pathog., 7, 2011
5Y4O	Cryo-EM structure of MscS channel, YnaI Descriptor: Low conductance mechanosensitive channel YnaI Authors: Zhang, Y, Yu, J. Deposit date: 2017-08-04 Release date: 2019-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A binding-block ion selective mechanism revealed by a Na/K selective channel. Protein Cell, 9, 2018
7T9F	Structure of VcINDY-apo Descriptor: DASS family sodium-coupled anion symporter Authors: Sauer, D.B, Marden, J.J, Song, J.M, Wang, D.N. Deposit date: 2021-12-19 Release date: 2022-05-25 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Structural basis of ion - substrate coupling in the Na + -dependent dicarboxylate transporter VcINDY. Nat Commun, 13, 2022
2KLT	Second Ca2+ binding domain of NCX1.3 Descriptor: Sodium/calcium exchanger 1 Authors: Hilge, M, Aelen, J, Foarce, A, Perrakis, A, Vuister, G.W. Deposit date: 2009-07-08 Release date: 2009-08-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism. Proc.Natl.Acad.Sci.USA, 106, 2009

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