7CN8
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![BU of 7cn8 by Molmil](/molmil-images/mine/7cn8) | Cryo-EM structure of PCoV_GX spike glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | Authors: | Wang, X, Yu, J, Zhang, S, Qiao, S, Zeng, J, Tian, L. | Deposit date: | 2020-07-30 | Release date: | 2021-03-03 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution. Nat Commun, 12, 2021
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1BWA
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![BU of 1bwa by Molmil](/molmil-images/mine/1bwa) | HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | Descriptor: | PROTEIN (HIV-1 PROTEASE), [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-3,3'-[[TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-D IYL] BIS(METHYLENE)]BIS[N-2-THIAZOLYLBENZAMIDE] | Authors: | Ala, P, Chang, C.H. | Deposit date: | 1998-09-22 | Release date: | 1998-10-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities. Biochemistry, 37, 1998
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1BO4
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![BU of 1bo4 by Molmil](/molmil-images/mine/1bo4) | CRYSTAL STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE: SERRATIA MARESCENS AMINOGLYCOSIDE 3-N-ACETYLTRANSFERASE | Descriptor: | COENZYME A, PROTEIN (SERRATIA MARCESCENS AMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE), SPERMIDINE | Authors: | Wolf, E, Vassilev, A, Makino, Y, Sali, A, Nakatani, Y, Burley, S.K. | Deposit date: | 1998-08-08 | Release date: | 1998-10-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase. Cell(Cambridge,Mass.), 94, 1998
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1BX3
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![BU of 1bx3 by Molmil](/molmil-images/mine/1bx3) | EFFECTS OF COMMONLY USED CRYOPROTECTANTS ON GLYCOGEN PHOSPHORYLASE ACTIVITY AND STRUCTURE | Descriptor: | PROTEIN (GLYCOGEN PHOSPHORYLASE B), PYRIDOXAL-5'-PHOSPHATE | Authors: | Tsitsanou, K.E, Oikonomakos, N.G, Zographos, S.E, Skamnaki, V.T, Gregoriou, M, Watson, K.A, Johnson, L.N, Fleet, G.W.J. | Deposit date: | 1999-10-13 | Release date: | 1999-10-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure. Protein Sci., 8, 1999
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1BOQ
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![BU of 1boq by Molmil](/molmil-images/mine/1boq) | PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | Descriptor: | PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION | Authors: | Peters, R.J, Shiau, A.K, Sohl, J.L, Anderson, D.E, Tang, G, Silen, J.L, Agard, D.A. | Deposit date: | 1998-08-05 | Release date: | 1998-08-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease. Biochemistry, 37, 1998
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1BP0
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![BU of 1bp0 by Molmil](/molmil-images/mine/1bp0) | THYMIDYLATE SYNTHASE R23I MUTANT | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, POTASSIUM ION, PROTEIN (THYMIDYLATE SYNTHASE) | Authors: | Morse, R, Finer-Moore, J, Stroud, R.M. | Deposit date: | 1998-08-11 | Release date: | 2000-01-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance". Biochemistry, 39, 2000
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5GK5
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![BU of 5gk5 by Molmil](/molmil-images/mine/5gk5) | Apo structure of fructose 1,6-bisphosphate aldolase from Escherichia coli at 1.9 angstrom resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, Fructose-bisphosphate aldolase class 2, GLYCEROL, ... | Authors: | Tran, T.H, Huynh, K.H, Ho, T.H, Kang, L.W. | Deposit date: | 2016-07-03 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Apo structure of fructose 1,6-bisphosphate aldolase from Escherichia coli at 1.9 angstrom resolution To Be Published
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7AJP
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![BU of 7ajp by Molmil](/molmil-images/mine/7ajp) | Crystal Structure of Human Adenovirus 56 Fiber Knob | Descriptor: | 1,2-ETHANEDIOL, Fiber, GLYCEROL, ... | Authors: | Strebl, M, Mindler, K, Stehle, T. | Deposit date: | 2020-09-29 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.382018 Å) | Cite: | Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46. Proc.Natl.Acad.Sci.USA, 118, 2021
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1EYM
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![BU of 1eym by Molmil](/molmil-images/mine/1eym) | FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX | Descriptor: | FK506 BINDING PROTEIN | Authors: | Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T. | Deposit date: | 2000-05-07 | Release date: | 2000-08-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A ligand-reversible dimerization system for controlling protein-protein interactions. Proc.Natl.Acad.Sci.USA, 97, 2000
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5O60
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![BU of 5o60 by Molmil](/molmil-images/mine/5o60) | Structure of the 50S large ribosomal subunit from Mycobacterium smegmatis | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2017-06-02 | Release date: | 2017-07-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | The Complete Structure of the Mycobacterium smegmatis 70S Ribosome. Cell Rep, 20, 2017
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1E8N
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![BU of 1e8n by Molmil](/molmil-images/mine/1e8n) | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, MUTANT, COMPLEXED WITH PEPTIDE | Descriptor: | GLYCEROL, PEPTIDE INHIBITOR, PROLYL ENDOPEPTIDASE | Authors: | Fulop, V. | Deposit date: | 2000-09-27 | Release date: | 2001-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of Prolyl Oligopeptidase Substrate/ Inhibitor Complexes. Use of Inhibitor Binding for Titration of the Catalytic Histidine Residue J.Biol.Chem., 276, 2001
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1EMC
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![BU of 1emc by Molmil](/molmil-images/mine/1emc) | |
1E94
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![BU of 1e94 by Molmil](/molmil-images/mine/1e94) | HslV-HslU from E.coli | Descriptor: | HEAT SHOCK PROTEIN HSLU, HEAT SHOCK PROTEIN HSLV, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Song, H.K, Hartmann, C, Ravishankar, R, Bochtler, M. | Deposit date: | 2000-10-07 | Release date: | 2000-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mutational Studies on Hslu and its Docking Mode with Hslv Proc.Natl.Acad.Sci.USA, 97, 2000
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5O3K
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![BU of 5o3k by Molmil](/molmil-images/mine/5o3k) | |
1EV1
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![BU of 1ev1 by Molmil](/molmil-images/mine/1ev1) | ECHOVIRUS 1 | Descriptor: | ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID | Authors: | Wien, M.W, Filman, D.J, Hogle, J.M. | Deposit date: | 1997-12-02 | Release date: | 1999-01-27 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Structure determination of echovirus 1. Acta Crystallogr.,Sect.D, 54, 1998
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1EAK
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![BU of 1eak by Molmil](/molmil-images/mine/1eak) | Catalytic domain of proMMP-2 E404Q mutant | Descriptor: | 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, INHIBITOR PEPTIDE, ... | Authors: | Bergmann, U, Tuuttila, A, Tryggvason, K, Morgunova, E. | Deposit date: | 2001-07-12 | Release date: | 2002-08-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Crystal Structure of Human Mmp-2 Reveals a New P To be Published
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5O5L
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![BU of 5o5l by Molmil](/molmil-images/mine/5o5l) | |
5H2F
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![BU of 5h2f by Molmil](/molmil-images/mine/5h2f) | Crystal structure of the PsbM-deletion mutant of photosystem II | Descriptor: | (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Uto, S, Kawakami, K, Umena, Y, Iwai, M, Ikeuchi, M, Shen, J.R, Kamiya, N. | Deposit date: | 2016-10-15 | Release date: | 2017-03-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutual relationships between structural and functional changes in a PsbM-deletion mutant of photosystem II. Faraday Discuss., 198, 2017
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1E9L
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![BU of 1e9l by Molmil](/molmil-images/mine/1e9l) | |
1E9X
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![BU of 1e9x by Molmil](/molmil-images/mine/1e9x) | |
1EB7
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![BU of 1eb7 by Molmil](/molmil-images/mine/1eb7) | |
1EEO
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![BU of 1eeo by Molmil](/molmil-images/mine/1eeo) | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 | Descriptor: | ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B | Authors: | Sarmiento, M, Puius, Y.A, Vetter, S.W, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. | Deposit date: | 2000-02-01 | Release date: | 2001-02-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition. Biochemistry, 39, 2000
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5O9A
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![BU of 5o9a by Molmil](/molmil-images/mine/5o9a) | Crystal structure of the GluA2 ligand-binding domain (S1S2J-L504Y-N775S) in complex with glutamate and BPAM121 at 1.78 A resolution | Descriptor: | 1,2-ETHANEDIOL, 7-chloro-4-(2-fluoroethyl)-2,3-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, CHLORIDE ION, ... | Authors: | Laulumaa, S, Rovinskaja, K, Frydenvang, K.A, Kastrup, J.S. | Deposit date: | 2017-06-16 | Release date: | 2018-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | 7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. J. Med. Chem., 61, 2018
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1EFO
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![BU of 1efo by Molmil](/molmil-images/mine/1efo) | CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG) | Descriptor: | DNA (5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3') | Authors: | Sudarsanakumar, C, Xiong, Y, Sundaralingam, M. | Deposit date: | 2000-02-09 | Release date: | 2000-05-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag). J.Mol.Biol., 299, 2000
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5HPW
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![BU of 5hpw by Molmil](/molmil-images/mine/5hpw) | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Singh, R.P, Singh, A, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2016-01-21 | Release date: | 2016-04-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mode of binding of antithyroid drug, propylthiouracil to lactoperoxidase: Binding studies and structure determination To Be Published
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