1EEO
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2
Summary for 1EEO
Entry DOI | 10.2210/pdb1eeo/pdb |
Related | 1EEN |
Descriptor | PROTEIN TYROSINE PHOSPHATASE 1B, ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase, phosphorylation, inhibition, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031 |
Total number of polymer chains | 2 |
Total formula weight | 38716.22 |
Authors | Sarmiento, M.,Puius, Y.A.,Vetter, S.W.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. (deposition date: 2000-02-01, release date: 2001-02-01, Last modification date: 2023-11-15) |
Primary citation | Sarmiento, M.,Puius, Y.A.,Vetter, S.W.,Keng, Y.F.,Wu, L.,Zhao, Y.,Lawrence, D.S.,Almo, S.C.,Zhang, Z.Y. Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition. Biochemistry, 39:8171-8179, 2000 Cited by PubMed: 10889023DOI: 10.1021/bi000319w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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