1EEO
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN TYROSINE PHOSPHATASE 1B | polymer | 321 | 37349.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | PTP1B |
| 2 | B (B) | ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE | polymer | 11 | 1342.3 | 1 | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ser 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38691.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 38716.2 |
