1BP0
THYMIDYLATE SYNTHASE R23I MUTANT
Summary for 1BP0
Entry DOI | 10.2210/pdb1bp0/pdb |
Descriptor | PROTEIN (THYMIDYLATE SYNTHASE), POTASSIUM ION, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | methyltransferase, nucleotide biosynthesis, transferase |
Biological source | Lactobacillus casei |
Cellular location | Cytoplasm: P00469 |
Total number of polymer chains | 1 |
Total formula weight | 36933.70 |
Authors | Morse, R.,Finer-Moore, J.,Stroud, R.M. (deposition date: 1998-08-11, release date: 2000-01-12, Last modification date: 2023-08-09) |
Primary citation | Morse, R.J.,Kawase, S.,Santi, D.V.,Finer-Moore, J.,Stroud, R.M. Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance". Biochemistry, 39:1011-1020, 2000 Cited by PubMed: 10653645DOI: 10.1021/bi9918590 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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