PDB: 401 resultsInfo pagesStatus searchChemie searchBIRD

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7O6Y	Cryo-EM structure of respiratory complex I under turnover Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... Authors: Parey, K, Vonck, J. Deposit date: 2021-04-12 Release date: 2021-11-10 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Sci Adv, 7, 2021
7QSD	Bovine complex I in the active state at 3.1 A Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-03-02 Last modified: 2023-03-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7QSM	Bovine complex I in lipid nanodisc, Deactive-ligand (composite) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Chung, I, Bridges, H.R, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-05-25 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
7QSL	Bovine complex I in lipid nanodisc, Active-apo Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Chung, I, Bridges, H.R, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-05-25 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
7QSN	Bovine complex I in lipid nanodisc, Deactive-apo Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Chung, I, Bridges, H.R, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-05-25 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
7QSK	Bovine complex I in lipid nanodisc, Active-Q10 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Chung, I, Bridges, H.R, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-05-25 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (2.84 Å) Cite: Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
7QSO	Bovine complex I in lipid nanodisc, State 3 (Slack) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Chung, I, Bridges, H.R, Hirst, J. Deposit date: 2022-01-13 Release date: 2022-05-25 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
7ODG	Crystal structure of the O2-tolerant MBH-P242C from Ralstonia eutropha in its reduced state Descriptor: CHLORIDE ION, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... Authors: Schmidt, A, Kalms, J, Scheerer, P. Deposit date: 2021-04-29 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Resonance Raman spectroscopic analysis of the iron-sulfur cluster redox chain of the Ralstonia eutropha membrane-bound [NiFe]-hydrogenase J Raman Spectrosc, 2021
7P63	Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Closed state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-15 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P69	Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-15 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P62	Complex I from E. coli, DDM-purified, Apo, Resting state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-15 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7L	Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P61	Complex I from E. coli, DDM-purified, with NADH, Resting state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-15 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P64	Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-15 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7C	Complex I from E. coli, DDM/LMNG-purified, Apo, Open state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7E	Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7J	Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7M	Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7K	Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... Authors: Kravchuk, V, Kampjut, D, Sazanov, L. Deposit date: 2021-07-19 Release date: 2022-09-21 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7NZ1	Respiratory complex I from Escherichia coli - focused refinement of cytoplasmic arm Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... Authors: Kolata, P, Efremov, R.G. Deposit date: 2021-03-23 Release date: 2021-08-18 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation. Elife, 10, 2021
7NYR	Respiratory complex I from Escherichia coli - conformation 1 Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... Authors: Kolata, P, Efremov, R.G. Deposit date: 2021-03-23 Release date: 2021-08-25 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation. Elife, 10, 2021
7NYU	Respiratory complex I from Escherichia coli - conformation 2 Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... Authors: Kolata, P, Efremov, R.G. Deposit date: 2021-03-23 Release date: 2021-08-25 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation. Elife, 10, 2021
7NYV	Respiratory complex I from Escherichia coli - conformation 3 Descriptor: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... Authors: Kolata, P, Efremov, R.G. Deposit date: 2021-03-23 Release date: 2021-08-25 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation. Elife, 10, 2021
7ODH	Crystal structure of the O2-tolerant MBH-P242C from Ralstonia eutropha in its as-isolated state Descriptor: CHLORIDE ION, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... Authors: Schmidt, A, Kalms, J, Scheerer, P. Deposit date: 2021-04-29 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Resonance Raman spectroscopic analysis of the iron-sulfur cluster redox chain of the Ralstonia eutropha membrane-bound [NiFe]-hydrogenase J Raman Spectrosc, 2021
7R42	Bovine complex I in the presence of IM1761092, active class ii (Composite map) Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... Authors: Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. Deposit date: 2022-02-08 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023

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