6SLV
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![BU of 6slv by Molmil](/molmil-images/mine/6slv) | Fragment AZ-013 binding at the p53pT387/14-3-3 sigma interface | Descriptor: | 14-3-3 protein sigma, 4-(methylamino)-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... | Authors: | Ottmann, C, Wolter, M, Guillory, X, Leysen, S, Genet, S, Somsen, B, Patel, J, Castaldi, P. | Deposit date: | 2019-08-20 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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5OLP
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![BU of 5olp by Molmil](/molmil-images/mine/5olp) | Galacturonidase | Descriptor: | CALCIUM ION, Pectate lyase | Authors: | Basle, A, Luis, A.S, Gilbert, H.J. | Deposit date: | 2017-07-28 | Release date: | 2017-11-29 | Last modified: | 2018-12-12 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol, 3, 2018
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5OFA
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![BU of 5ofa by Molmil](/molmil-images/mine/5ofa) | Crystal structure of human MORC2 (residues 1-603) with spinal muscular atrophy mutation T424R | Descriptor: | MAGNESIUM ION, MORC family CW-type zinc finger protein 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Douse, C.H, Liu, Y, Modis, Y. | Deposit date: | 2017-07-10 | Release date: | 2018-02-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms. Nat Commun, 9, 2018
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6SNK
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![BU of 6snk by Molmil](/molmil-images/mine/6snk) | Crystal structure of the Collagen VI alpha3 N2 domain | Descriptor: | Collagen alpha-3(VI) chain | Authors: | Gebauer, J.M, Degefa, H.S, Paulsson, M, Wagener, R, Baumann, U. | Deposit date: | 2019-08-26 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. J.Biol.Chem., 295, 2020
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5OF5
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![BU of 5of5 by Molmil](/molmil-images/mine/5of5) | Cu nitrite reductase serial data at varying temperatures | Descriptor: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | Deposit date: | 2017-07-10 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
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6SNP
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![BU of 6snp by Molmil](/molmil-images/mine/6snp) | Crystal structures of human PGM1 isoform 2 | Descriptor: | MAGNESIUM ION, Phosphoglucomutase-1 | Authors: | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | Deposit date: | 2019-08-27 | Release date: | 2020-04-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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6SQG
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![BU of 6sqg by Molmil](/molmil-images/mine/6sqg) | Crystal structure of viral rhodopsin OLPVRII | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, RETINAL, ... | Authors: | Gushchin, I, Kovalev, K, Bratanov, D, Polovinkin, V, Astashkin, R, Popov, A, Bourenkov, G, Gordeliy, V. | Deposit date: | 2019-09-03 | Release date: | 2019-11-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unique structure and function of viral rhodopsins. Nat Commun, 10, 2019
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7C46
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5OFC
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![BU of 5ofc by Molmil](/molmil-images/mine/5ofc) | Cu nitrite reductase serial data at varying temperatures 190K 21.65MGy | Descriptor: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | Deposit date: | 2017-07-10 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
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6SO1
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![BU of 6so1 by Molmil](/molmil-images/mine/6so1) | Fragment N13569a in complex with MAP kinase p38-alpha | Descriptor: | 1-(1,3-benzodioxol-5-yl)-~{N}-[[(2~{R})-oxolan-2-yl]methyl]methanamine, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Nichols, C.E, De Nicola, G.F. | Deposit date: | 2019-08-28 | Release date: | 2019-10-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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5OGS
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![BU of 5ogs by Molmil](/molmil-images/mine/5ogs) | Crystal structure of human AND-1 SepB domain | Descriptor: | MALONATE ION, WD repeat and HMG-box DNA-binding protein 1 | Authors: | Pellegrini, L, Simon, A.C. | Deposit date: | 2017-07-13 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | The human CTF4-orthologue AND-1 interacts with DNA polymerase alpha /primase via its unique C-terminal HMG box. Open Biol, 7, 2017
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5OFT
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6SR7
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![BU of 6sr7 by Molmil](/molmil-images/mine/6sr7) | Structure of the U1A variant A1-98 Y31H/Q36R/K98W | Descriptor: | SULFATE ION, U1 small nuclear ribonucleoprotein A | Authors: | Rosenbach, H, Span, I. | Deposit date: | 2019-09-05 | Release date: | 2020-05-13 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Expanding crystallization tools for nucleic acid complexes using U1A protein variants. J.Struct.Biol., 210, 2020
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6SOO
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5OGT
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5OHM
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![BU of 5ohm by Molmil](/molmil-images/mine/5ohm) | K33-specific affimer bound to K33 diUb | Descriptor: | K33-specific affimer, POLYETHYLENE GLYCOL (N=34), Polyubiquitin-C | Authors: | Michel, M.A, Komander, D. | Deposit date: | 2017-07-17 | Release date: | 2017-10-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling. Mol. Cell, 68, 2017
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6ST1
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7C8L
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![BU of 7c8l by Molmil](/molmil-images/mine/7c8l) | Hybrid designing of potent inhibitors of Striga strigolactone receptor ShHTL7 | Descriptor: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, GLYCEROL, Hyposensitive to light 7, ... | Authors: | Shahul Hameed, U.F, Arold, S.T. | Deposit date: | 2020-06-02 | Release date: | 2021-06-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Rational design of Striga hermonthica-specific seed germination inhibitors. Plant Physiol., 188, 2022
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5OIF
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![BU of 5oif by Molmil](/molmil-images/mine/5oif) | InhA (T2A mutant) complexed with 1-benzyl-3-methyl-1H-pyrazol-5-amine | Descriptor: | 5-methyl-2-(phenylmethyl)pyrazol-3-amine, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Convery, M.A. | Deposit date: | 2017-07-18 | Release date: | 2018-02-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA. ChemMedChem, 13, 2018
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6SUJ
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6SVL
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![BU of 6svl by Molmil](/molmil-images/mine/6svl) | |
7C91
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![BU of 7c91 by Molmil](/molmil-images/mine/7c91) | Blasnase-T13A with D-asn | Descriptor: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | Authors: | Lu, F, Ran, T, Jiao, L, Wang, W. | Deposit date: | 2020-06-04 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity. J.Agric.Food Chem., 69, 2021
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5OJP
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![BU of 5ojp by Molmil](/molmil-images/mine/5ojp) | YCF48 bound to D1 peptide | Descriptor: | Ycf48-like protein | Authors: | Michoux, F, Nixon, P.J, Murray, J.W. | Deposit date: | 2017-07-22 | Release date: | 2018-08-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a seven-bladed beta-propeller protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5OKA
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![BU of 5oka by Molmil](/molmil-images/mine/5oka) | Non-conservatively refined structure of Gan1D-E170Q, a catalytic mutant of a 6-phospho-beta-galactosidase from Geobacillus stearothermophilus | Descriptor: | GLYCEROL, IMIDAZOLE, Putative 6-phospho-beta-galactobiosidase | Authors: | Lansky, S, Zehavi, A, Shoham, Y, Shoham, G. | Deposit date: | 2017-07-25 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural basis for enzyme bifunctionality - the case of Gan1D from Geobacillus stearothermophilus. FEBS J., 284, 2017
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6TUO
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![BU of 6tuo by Molmil](/molmil-images/mine/6tuo) | |